Acetyl Coenzyme A

• Aids in providing balance in endocrine system and in amino acid, electrolyte and intermediary metabolism.† †Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.

DIRECTIONS: Adults: 2 to 3 sprays orally, three times daily. Children under twelve one half adult dosage. Do not take within 15 minutes of consuming food, beverage or brushing teeth. Consult a physician for use in children under 12 years of age.

Professional Use Only If pregnant or breast-feeding, ask a health professional before use. In case of overdose, get medical help or contact a Poison Control Center right away. If condition worsens, seek medical attention. KEEP OUT OF REACH OF CHILDREN Do not use if tamper evident seal is broken or missing. Store in a cool place after opening

Recent PubMed references pinned to Acetyl Coenzyme A as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• AcuB senses cellular energy charge to coordinate acetyl-CoA synthesis in bacteria.
  Nature communications · 2026 · Janetzky M, Geist N, Schulze S, et al.
  PMID 42031755DOI 10.1038/s41467-026-71006-w
• Cytosolic AcCoA: a metabolic signal bridging nutrient sensing and mitophagy.
  Trends in biochemical sciences · 2026 · Chen J, Pan X
  PMID 41905847DOI 10.1016/j.tibs.2026.01.007
• SREBP2 links ACSS2-dependent acetyl-CoA biosynthesis to metaboloepigenetic activation of hepatic stellate cells and liver fibrosis.
  Metabolism: clinical and experimental · 2026 · Wang Y, Kang A, Wang S, et al.
  PMID 41887397DOI 10.1016/j.metabol.2026.156597
• Fatty acid oxidation drives acetyl-CoA-dependent H3K9ac reprogramming to promote adaptive resistance to BRAF(V600E) inhibition in thyroid cancer.
  Cell death & disease · 2026 · Wang X, Zhang J, Yuan J, et al.
  PMID 41862440DOI 10.1038/s41419-026-08575-7
• Impaired Acetyl-CoA Compartmentalization Drives a Futile Lipogenic-Oxidative Cycle in N88S Seipinopathy.
  Cells · 2026 · Moreira V, van Roermund CWT, Costa V, et al.
  PMID 41827830DOI 10.3390/cells15050395
• A FRET-based ratiometric nanosensor for monitoring Acetyl-CoA levels in living cells.
  Archives of biochemistry and biophysics · 2026 · Masroor S, Soleja N, Jairajpuri MA, et al.
  PMID 41825808DOI 10.1016/j.abb.2026.110792
• Acetyl-CoA Homeostasis via Mitochondrial Pyruvate Oxidation Governs Survival, Transcriptional Fidelity and Neural Specification in Primed Human Embryonic Stem Cells.
  Journal of cellular physiology · 2026 · Zhong N, Liu Y, Shao M, et al.
  PMID 41705723DOI 10.1002/jcp.70153
• Cholinergic Phenotypes of Acetyl-CoA with ATP-Citrate Lyase Link.
  International journal of molecular sciences · 2026 · Gul-Hinc S, Jankowska-Kulawy A, Szutowicz A, et al.
  PMID 41596431DOI 10.3390/ijms27020782

The 10 most recently updated of 28 ClinicalTrials.gov registrations naming Acetyl Coenzyme A as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Investigating the Production of Lipoproteins and Acetyl-CoA During a Ketogenic Diet
  Completed · Interventional · 4 enrolled · Touro University, California
  NCT03901014updated 2026-05-18
• Efficiency of a Composite Personalised Care on Functional Outcome in Early Psychosis
  Recruiting · Phase 3 · Interventional · 500 enrolled · Centre Hospitalier St Anne
  NCT05796401updated 2026-04-20
• Vision Preservation and Restoration Following a 6 Month Trial of GlaucoCetin
  Terminated · Interventional · 12 enrolled · Wills Eye
  NCT04784234updated 2025-12-23
• LIver FRAilty Management IN Cirrhosis (LIFRAMIN)
  Active not recruiting · Interventional · 30 enrolled · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
  NCT06573229updated 2025-08-13
• Lactoferrin Use in ICU Patients
  Not yet recruiting · Phase 4 · Interventional · 660 enrolled · Mansoura University Hospital
  NCT05936528updated 2025-07-28
• Oxaloacetate in Myasthenia Gravis
  Withdrawn · Phase 1 · Interventional · 0 enrolled · University of Kansas Medical Center
  NCT04965987updated 2025-07-11
• The Role of Glutathione Deficiency and MSIDS Variables in Long COVID-19
  Withdrawn · Early phase 1 · Interventional · 0 enrolled · University of California, Irvine
  NCT05371288updated 2024-11-05
• A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion
  Completed · Phase 3 · Interventional · 70 enrolled · Nantes University Hospital
  NCT03197194updated 2024-01-24
• To Evaluate the Efficacy and Safety of HSK16149 With L-carnitine in Diabetic Peripheral Neuralgia Patients in China
  Unknown · Interventional · 136 enrolled · Haisco Pharmaceutical Group Co., Ltd.
  NCT06122012updated 2023-11-08
• Investigation of The Effectiveness of Antioxidant Therapy in Oligoasthenoteratozoospermic Infertile Men
  Completed · Interventional · 48 enrolled · Ondokuz Mayıs University
  NCT06042738updated 2023-09-21

Frequently asked questions

What is Acetyl Coenzyme A used for?

According to FDA labeling, Acetyl Coenzyme A carries indications including: Aids in providing balance in endocrine system and in amino acid, electrolyte and intermediary metabolism.† †Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.