Acetylcarnitine

Mechanism-of-action class: Biological Macromolecular Activity.

• Take 15 minutes before meals.

DIRECTIONS Take 15 minutes before meals Adults and children 12 years and older 20 drops in a little water 2 times per day Children between 12 years and 6 years of age. 10 drops in a little water 2 times per day Children under 6 years 5 drops in a glass of water 2 times per day

Stop use and ask doctor if symptoms persist more than 5 days. If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Contains ethyl alcohol 30%

Recent PubMed references pinned to Acetylcarnitine as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Metabolomics Highlights Reduced Glutamate and Acetylcarnitine in the Amniotic Fluid of Cytomegalovirus-Infected Pregnant Women.
  Journal of proteome research · 2026 · Costanzo M, Miceli M, Campesi I, et al.
  PMID 41841159DOI 10.1021/acs.jproteome.5c01108
• Effects of Acetyl-l-Carnitine on the Mitophagy in the Spinal Cord Injury Progression Through PINK/Parkin Pathway.
  Journal of biochemical and molecular toxicology · 2026 · Shen J, Zhao L, He G, et al.
  PMID 41832947DOI 10.1002/jbt.70778
• Acetyl-carnitine improves hyperactivity and learning deficits in KAT6A haploinsufficient mice.
  Life science alliance · 2026 · Eccles S, Vanyai HK, Bergamasco MI, et al.
  PMID 41702672DOI 10.26508/lsa.202503549
• L-Carnitine and Acetyl-L-Carnitine in Drug Poisonings: A Systematic Review of Clinical and Experimental Evidence.
  Journal of applied toxicology : JAT · 2026 · Rezaee H, Abbasgholizadeh F
  PMID 41692009DOI 10.1002/jat.70095
• The mechanism of acetyl-L-carnitine on colorectal cancer and its metabolomic study.
  Journal of pharmaceutical and biomedical analysis · 2026 · Ning J, Cai C, Fan X, et al.
  PMID 41610723DOI 10.1016/j.jpba.2026.117363
• Low Bioavailability and High TMAO Production: Novel Insights Into Acetylcarnitine and Carnitine Metabolism.
  Molecular nutrition & food research · 2025 · Krims-Davis K, Ozola M, Razzivina V, et al.
  PMID 41243468DOI 10.1002/mnfr.70316
• The vital impact of acetyl-L-carnitine and selenium-fortified Saccharomyces cerevisiae on biochemical parameters in Awassi ewes.
  Open veterinary journal · 2025 · Abdulazeez ST, Alsaadi SAA
  PMID 41200339DOI 10.5455/OVJ.2025.v15.i9.77
• Acetylcarnitine in cerebrospinal fluid and blood as a protective factor for neuromyelitis optica spectrum disorders: a mendelian randomization study.
  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025 · Xie Z, Gai F, Liu L, et al.
  PMID 41102548DOI 10.1007/s10072-025-08432-z

The 10 most recently updated of 63 ClinicalTrials.gov registrations naming Acetylcarnitine as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• The Effects of Acetyl-L-Carnitine and Myo/Chiro-Inositol in Patients With PCOS
  Completed · Interventional · 120 enrolled · Khyber Medical University Peshawar
  NCT05767515updated 2026-02-09
• Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS
  Recruiting · Phase 2 · Phase 3 · Interventional · 246 enrolled · Mario Negri Institute for Pharmacological Research
  NCT06126315updated 2025-09-25
• LIver FRAilty Management IN Cirrhosis (LIFRAMIN)
  Active not recruiting · Interventional · 30 enrolled · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
  NCT06573229updated 2025-08-13
• Pilot Study: Impact of Biomarker-Guided Dietary Supplementation on Quality-of-Life Measures in Subjects With Chronic Pain
  Recruiting · Phase 2 · Interventional · 75 enrolled · Ethos Research & Development
  NCT06247813updated 2024-09-19
• Clinical Trial to Evaluate Safety and Efficacy of Jalosome® Soothing Gel.
  Unknown · Interventional · 57 enrolled · Welcare Industries SpA
  NCT05284487updated 2024-02-26
• Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS
  Completed · Interventional · 120 enrolled · Khyber Medical University Peshawar
  NCT05653895updated 2024-02-23
• To Evaluate the Efficacy and Safety of HSK16149 With L-carnitine in Diabetic Peripheral Neuralgia Patients in China
  Unknown · Interventional · 136 enrolled · Haisco Pharmaceutical Group Co., Ltd.
  NCT06122012updated 2023-11-08
• Combined Rehabilitation With ALA, ALC, Resveratrol and Vitamin D in Discogenic Sciatica in Young People
  Completed · Interventional · 130 enrolled · University of Palermo
  NCT06078163updated 2023-10-11
• Investigation of The Effectiveness of Antioxidant Therapy in Oligoasthenoteratozoospermic Infertile Men
  Completed · Interventional · 48 enrolled · Ondokuz Mayıs University
  NCT06042738updated 2023-09-21
• Comparison of Acetyl- L- Carnitine& Folic Acid Versus Coenzyme Q10& Folic Acid on Semen& Hormonal Parameters& Semen Oxidative Status in Patients of Primary Infertility. A Double Blind Randomized Clinical Trial
  Completed · Phase 2 · Interventional · 86 enrolled · Khyber Medical University Peshawar
  NCT05616000updated 2022-11-30

Frequently asked questions

How does Acetylcarnitine work?

Mechanism-of-action class: Biological Macromolecular Activity.

What is Acetylcarnitine used for?

According to FDA labeling, Acetylcarnitine carries indications including: Take 15 minutes before meals.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Acetylcarnitine?

Acetylcarnitine is classified as Other psychostimulants and nootropics, Biological Macromolecular Activity, Cellular Activity Alteration, Sperm Motility Alteration.