Acetylcholine
/api/v1/drug/acetylcholineMechanism of action
Sourced from openFDAMechanism-of-action classes: Cholinergic Agonists; Cholinergic Muscarinic Agonists.
Indications
Sourced from openFDA- For temporary relief of symptoms including dizziness, chest congestion, cough, fatigue, rash, itching, headache and poor memory.** **These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.ICD-10: R05.9, R51.9
Dosage & administration
Sourced from openFDADIRECTIONS: 1-10 drops under the tongue, 3 times a day or as directed by a health professional. Consult a physician for use in children under 12 years of age.
Warnings & precautions
Sourced from openFDAKeep out of reach of children. In case of overdose, contact a physician or Poison Control Center right away. If pregnant or breast-feeding, ask a health professional before use. Tamper seal: "Sealed for Your Protection." Do not use if seal is broken or missing.
Approval history
Sourced from openFDA- Sep 22, 1993NDANDA020213Bausch And Lomb
FAERS reports
- 1Depression3631%
- 2Dyspnoea3530%
- 3Pneumonia3530%
- 4Malaise3430%
- 5Rhinorrhoea3430%
- 6Sinusitis3430%
- 7Sleep Disorder3430%
- 8Sleep Disorder Due To A General Medical Condition3430%
- 9Therapeutic Product Effect Incomplete3430%
- 10Anxiety3329%
- 11Asthma3329%
- 12Breast Cancer3329%
- 13Chest Discomfort3329%
- 14Chronic Obstructive Pulmonary Disease3329%
- 15Cough3329%
Literature
Recent PubMed references pinned to Acetylcholine as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Tuft cell acetylcholine: how parasites make gut talk to brain.Trends in parasitology · 2026 · Bas J, Jay PPMID 42161688DOI 10.1016/j.pt.2026.05.004
- The Effect of the Anticonvulsant Topiramate on Acetylcholine-Induced Calcium Signals is Linked to Sirt-1 Activity.The European journal of neuroscience · 2026 · Kümmel MLPMID 42052976DOI 10.1111/ejn.70514
- Cholinergic signals and antibodies.Science signaling · 2026 · Foley JFPMID 41980070DOI 10.1126/scisignal.aeh8929
- Dynamic cholinergic signaling differentially desynchronizes cortical microcircuits dependent on modulation rate and network connectivity.PLoS computational biology · 2026 · Pandian S, Rich SPMID 41961884DOI 10.1371/journal.pcbi.1013252
- A Single-Vesicle Electroanalytical Approach Uncovers Deficits of Vesicular Acetylcholine Content in Alzheimer's Disease.Journal of the American Chemical Society · 2026 · Jiang Y, Liu L, Xiong M, et al.PMID 41955089DOI 10.1021/jacs.5c22608
- Acetylcholine demixes heterogeneous dopamine signals for learning and moving.Nature neuroscience · 2026 · Jang HJ, McMahon Ward R, Golden CEM, et al.PMID 41882194DOI 10.1038/s41593-026-02227-x
- Acetylcholine-protective activity of chemo-enzymatically synthesized aryl vicinal diols and hydroxy ketones.Bioorganic chemistry · 2026 · Grzelczyk J, Pérez-Sánchez H, Carmena-Bargueño M, et al.PMID 41864079DOI 10.1016/j.bioorg.2026.109770
- The central cholinergic system as a therapeutic target in Parkinson's disease.Journal of Parkinson's disease · 2026 · Miller SJ, Yue JS, Bozal SB, et al.PMID 41854085DOI 10.1177/1877718X261427270
Clinical trials
The 10 most recently updated of 244 ClinicalTrials.gov registrations naming Acetylcholine as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Hot Flashes and Neurovascular Function in WomenRecruiting · Interventional · 120 enrolled · Mayo ClinicNCT05193968updated 2026-06-12
- Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive ImpairmentNot yet recruiting · Interventional · 84 enrolled · Posit Science CorporationNCT07243600updated 2026-06-11
- A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)Recruiting · Phase 4 · Interventional · 150 enrolled · Alpha Cognition, IncNCT07633470updated 2026-06-08
- Phase 3 Study to Assess the Efficacy and Safety of Batoclimab as Induction and Maintenance Therapy in Adult Participants With Generalized Myasthenia GravisActive not recruiting · Phase 3 · Interventional · 240 enrolled · Immunovant Sciences GmbHNCT05403541updated 2026-06-05
- Botox or Botox With Esophageal Dilation in Patients With AchalasiaEnrolling by invitation · Phase 4 · Interventional · 50 enrolled · Vanderbilt University Medical CenterNCT03654066updated 2026-05-27
- Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia GravisRecruiting · Phase 3 · Interventional · 231 enrolled · Immunovant Sciences GmbHNCT07039916updated 2026-05-22
- Invasive Evaluation and Phenotype-Guided Treatment of ANOCA in WomenNot yet recruiting · Interventional · 50 enrolled · Hospital de Clínicas Dr. Manuel QuintelaNCT07593157updated 2026-05-18
- Role of the Striatal Cholinergic System in the Pathophysiology of DystoniaCompleted · Interventional · 40 enrolled · University Hospital, BordeauxNCT02727361updated 2026-05-14
- Imaging of Vesicular Acetylcholine and Dopamine Transporters in Dementia With Lewy BodiesCompleted · Interventional · 34 enrolled · University Hospital, BordeauxNCT00917709updated 2026-05-14
- The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood FlowTerminated · Interventional · 31 enrolled · University Hospital, LinkoepingNCT04777383updated 2026-05-13
Frequently asked questions
- How does Acetylcholine work?
- Mechanism-of-action classes: Cholinergic Agonists; Cholinergic Muscarinic Agonists.
- What is Acetylcholine used for?
- According to FDA labeling, Acetylcholine carries indications including: For temporary relief of symptoms including dizziness, chest congestion, cough, fatigue, rash, itching, headache and poor memory.** **These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Acetylcholine?
- Acetylcholine is classified as Parasympathomimetics, Cholinergic Receptor Agonist, Cholinergic Agonists, Cholinergic Muscarinic Agonists, Pupillary Constriction.
- What are the brand names for Acetylcholine?
- Acetylcholine is marketed under brand names including Miochol.
acetylcholine is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.