Aconite
US-FDASourced from openFDA
GET
/api/v1/drug/aconiteIndications
Sourced from openFDA- & USAGE SECTION Formulated for susceptibility to colds.
Dosage & administration
Sourced from openFDADOSAGE & ADMINISTRATION SECTION Directions: Adults 4 pellets; Children (4-12 years) 2 pellets; Dissolve under the tongue. Take every half hour as needed, or 4 times a day.
Warnings & precautions
Sourced from openFDASECTION Warning : Consult a doctor if symptoms persist more than 3 days or worsen. If pregnant or nursing , ask a doctor before use. Keep out of reach of children. Do not use if tamper-evident band is missing or broken.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
24 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Completed Suicide417%
- 2Diarrhoea417%
- 3Headache417%
- 4Muscle Spasms417%
- 5Paraesthesia417%
- 6Tinnitus417%
- 7Decreased Appetite313%
- 8Hypersensitivity313%
- 9Neuropathy Peripheral313%
- 10Arthralgia28.3%
- 11Bladder Disorder28.3%
- 12Bowel Movement Irregularity28.3%
- 13Burning Sensation28.3%
- 14Cardio-respiratory Arrest28.3%
- 15Condition Aggravated28.3%
Literature
Recent PubMed references pinned to Aconite as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Development and Characterization of Ginsenoside-Aconitum Lipidic Cubic Nanoparticle-Loaded Dissolving Microneedles for Enhanced Transdermal Anti-inflammatory Therapy.AAPS PharmSciTech · 2026 · Liu Y, Wang Y, Wu S, et al.PMID 42159932DOI 10.1208/s12249-026-03450-2
- A Bioactive Component from Aconitum pendulum Attenuates Rheumatoid Arthritis-Related Inflammation in Rats via PI3K/Akt Pathway Regulation.Journal of visualized experiments : JoVE · 2026 · Dong D, Jiang SS, Yu H, et al.PMID 42113788DOI 10.3791/70473
- Immobilized enzyme reactor coupled with UHPLC-QTOF-MS for screening acetylcholinesterase inhibitory leads from Aconitum carmichaelii aerial parts.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2026 · Mei D, Su H, Zhao Y, et al.PMID 41962350DOI 10.1016/j.jchromb.2026.125058
- Sczukinitines C - I, new C(20)-diterpenoid alkaloids from Aconitum sczukinii.Fitoterapia · 2026 · Ye MZ, Deng ZY, Liu YQ, et al.PMID 41946415DOI 10.1016/j.fitote.2026.107230
- Aconitum septentrionale Koelle extract alleviates cigarette smoke and lipopolysaccharide-induced chronic obstructive pulmonary disease in mice by modulating the MAPK pathway.Journal of ethnopharmacology · 2026 · Bao F, Wang N, Guo Q, et al.PMID 41864552DOI 10.1016/j.jep.2026.121389
- Aconiti Lateralis Radix Praeparata active ingredients of Heishunpian potential on LPS-induced Nrf-2/NQO1/HO-1 and Smad3/Akt/p38 signalling pathways in chronic obstructive pulmonary disease: a network pharmacology study.Journal of molecular histology · 2026 · Wang Y, Niu X, Guo J, et al.PMID 41793558DOI 10.1007/s10735-026-10761-y
- Mechanistic insights into compatibility-based detoxification of Fengshi Gutong Capsules through network toxicology and in vivo validation.Journal of ethnopharmacology · 2026 · Sun Y, Liu J, Zuo Y, et al.PMID 41786059DOI 10.1016/j.jep.2026.121478
- Comprehensive analysis of 73 Aconitum chloroplast genomes reveals their structure, codon usage bias, and phylogenetic relationships within family Ranunculaceae.Scientific reports · 2026 · Kakkar RA, Sharma GPMID 41781487DOI 10.1038/s41598-026-40105-5
Clinical trials
The 10 most recently updated of 21 ClinicalTrials.gov registrations naming Aconite as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Development of an Aptamer-based Lateral Flow Device for Point-of-care Detection of Toxic Chinese Medicine Herbs (ALPTH Project)Recruiting · Observational · 90 enrolled · The University of Hong KongNCT07456592updated 2026-03-11
- Traditional Chinese Medicine Hand-Foot Soak for Chemotherapy-Induced Peripheral Neuropathy and Hand-Foot SyndromeNot yet recruiting · Observational · 300 enrolled · Peking University Third HospitalNCT07375446updated 2026-01-29
- Clinical Trial With Aconite Pain Oil in Oncology Patients Under Chemotherapy to Prevent CIPN Grade-II, to Reduce Symptoms and to Improve the Quality of Life of Patients With CIPNRecruiting · Phase 3 · Interventional · 350 enrolled · WALA Heilmittel GmbHNCT06186479updated 2025-09-02
- A Study of Shengbai Oral Formula to Assess Safety and Alleviation of Adverse Effects in Cancer Patients Undergoing ChemotherapyRecruiting · Interventional · 30 enrolled · Sutter HealthNCT06706752updated 2025-05-15
- Shenfu Injection Modulates Carotid Elasticity in Septic ShockNot yet recruiting · Phase 4 · Interventional · 48 enrolled · First Affiliated Hospital of Wannan Medical CollegeNCT06915506updated 2025-04-08
- The Preventive Effect of Shenfu Injection on Myocardial Dysfunction in SepsisRecruiting · Phase 4 · Interventional · 440 enrolled · First Affiliated Hospital of Wannan Medical CollegeNCT06898723updated 2025-03-27
- Pogejiuxin Decoction Combination of Conventional Western Medicine for the Treatment of Heart Failure With Preserved Ejection FractionCompleted · Interventional · 100 enrolled · Chongqing Traditional Chinese Medicine HospitalNCT06629246updated 2024-10-08
- A Single-blind RCT to Investigate the Effect of a Novel Herbal Patch for the Treatment of PFUnknown · Interventional · 24 enrolled · Chinese University of Hong KongNCT05584046updated 2024-02-15
- Efficacy of Jianpi Qushi Huatan Decoction in the Treatment of Polycystic Ovary SyndromeUnknown · Phase 1 · Phase 2 · Interventional · 68 enrolled · Jiangxi University of Traditional Chinese MedicineNCT05976295updated 2023-09-08
- Efficacy of Bushen Huatan Decoction in the Treatment of Polycystic Ovary SyndromeUnknown · Phase 1 · Phase 2 · Interventional · 68 enrolled · Jiangxi University of Traditional Chinese MedicineNCT05976308updated 2023-09-08
Frequently asked questions
- What is Aconite used for?
- According to FDA labeling, Aconite carries indications including: & USAGE SECTION Formulated for susceptibility to colds.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
Note. Data for
aconite is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.