Arsenic

Mechanism-of-action class: Unknown Cellular or Molecular Interaction.

• Relieves diarrhea with weakness * Uses: See symptoms on front panel.

Adults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor.

• Sep 25, 2000NDANDA021248Cephalon
• Aug 31, 2018ANDAANDA208231Fresenius Kabi Usa
• Nov 13, 2018ANDAANDA206228Zydus Pharms
• Nov 13, 2018ANDAANDA210802Amring Pharms
• Nov 15, 2018ANDAANDA209315Ingenus Pharms Llc
• Nov 15, 2018ANDAANDA209780Nexus
• Jan 25, 2021ANDAANDA210739Amneal
• Oct 7, 2021ANDAANDA215059Gland

1. 1Fatigue3075.9%
2. 2Nausea2855.5%
3. 3Electrocardiogram Qt Prolonged2675.2%
4. 4Diarrhoea2544.9%
5. 5Headache2434.7%
6. 6Off Label Use2374.6%
7. 7Drug Ineffective2234.3%
8. 8Pain2234.3%
9. 9Dyspnoea2214.3%
10. 10Differentiation Syndrome2204.2%
11. 11Pyrexia1953.8%
12. 12Dizziness1913.7%
13. 13Arthralgia1773.4%
14. 14Vomiting1743.4%
15. 15Pneumonia1683.2%

Recent PubMed references pinned to Arsenic as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Exogenous Syringic Acid Mitigates Arsenic Toxicity in Lettuce Plants: A Physiological, Antioxidant, and Metabolomics Investigation.
  Physiologia plantarum · 2026 · Salehi H, Alp-Turgut FN, Zengin G, et al.
  PMID 42259367DOI 10.1111/ppl.70964
• Silymarin Attenuates Arsenic-Induced Mitochondrial Dysfunction and Suppression of Nrf2/ARE-Regulated Phase II Detoxification Genes in Rat Brain.
  Journal of biochemical and molecular toxicology · 2026 · Verma A, Soni M, Nandal K, et al.
  PMID 42224437DOI 10.1002/jbt.70928
• Computational Analysis of Differentially Expressed Genes in Arsenic-Induced Carcinogenesis and Their Effect on Human Repair Mechanisms.
  Environmental and molecular mutagenesis · 2026 · Parida L, Patel TN
  PMID 42219787DOI 10.1002/em.70060
• Coupling mechanisms between microbial arsenic metabolism and carbon cycling in arsenic-contaminated groundwater.
  Journal of environmental sciences (China) · 2026 · Xiao Y, Ouyang Q, Wen X, et al.
  PMID 42217876DOI 10.1016/j.jes.2025.10.032
• [Effects and Mechanisms of Organic Fertilizer on the Accumulation and Transport of Arsenic and Cadmium in the Soil-rice System].
  Huan jing ke xue= Huanjing kexue · 2026 · Yang YY, Xiao XY, Yang AP, et al.
  PMID 42191625DOI 10.13227/j.hjkx.202503085
• Time-dependent post-exposure self-recovery rescues arsenic-induced behavioral and biochemical alterations in mice.
  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2026 · Hossain S, Sarder SJ, Suchona TI, et al.
  PMID 42191075DOI 10.1016/j.fct.2026.116174
• Exploring a critical time window for FOXM1-driven bladder injury in chronic arsenic exposure.
  Ecotoxicology and environmental safety · 2026 · Kan H, Chen M, Hu W, et al.
  PMID 42190387DOI 10.1016/j.ecoenv.2026.120312
• Microbial Transformation of Humic Acid Components Modulates Reduction of Structurally Bound As(V) via Electron Shuttling.
  Environmental science & technology · 2026 · Su Z, Guo H, Feng X, et al.
  PMID 42179322DOI 10.1021/acs.est.6c03416

The 10 most recently updated of 211 ClinicalTrials.gov registrations naming Arsenic as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia
  Recruiting · Phase 3 · Interventional · 150 enrolled · Quetzal Therapeutics
  NCT07504458updated 2026-06-11
• Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, China
  Completed · Observational · 9,759 enrolled · National Cancer Institute (NCI)
  NCT00340405updated 2026-06-05
• Lisaftoclax for Prevention of Differentiation Syndrom in Acute Promyelocytic Leukemia Patients
  Not yet recruiting · Phase 2 · Phase 3 · Interventional · 60 enrolled · The Affiliated People's Hospital of Ningbo University
  NCT07597941updated 2026-06-04
• Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia
  Completed · Phase 3 · Interventional · 133 enrolled · Technische Universität Dresden
  NCT02688140updated 2026-05-29
• Tretinoin and Arsenic Trioxide With or Without Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia
  Recruiting · Phase 2 · Interventional · 151 enrolled · M.D. Anderson Cancer Center
  NCT01409161updated 2026-05-20
• Strong Heart Water Study
  Active not recruiting · Interventional · 57 enrolled · Johns Hopkins Bloomberg School of Public Health
  NCT03725592updated 2026-05-12
• Mitigation Efforts in Arsenic Exposure With Folic Acid Supplementation
  Enrolling by invitation · Interventional · 100 enrolled · University of Alabama at Birmingham
  NCT05656664updated 2026-04-30
• Table-Top Water Pitcher to Reduce Arsenic Exposure Among Well Users in New Hampshire
  Recruiting · Interventional · 20 enrolled · Trustees of Dartmouth College
  NCT07103356updated 2026-03-24
• Understanding Effects of Folic Acid on the Methylosome and Transcriptome of Women With Spina Bifida Affected Pregnancies
  Completed · Interventional · 69 enrolled · Boston Children's Hospital
  NCT05500690updated 2026-03-17
• Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia
  Active not recruiting · Phase 3 · Interventional · 158 enrolled · Children's Oncology Group
  NCT02339740updated 2026-02-18

Frequently asked questions

How does Arsenic work?

Mechanism-of-action class: Unknown Cellular or Molecular Interaction.

What is Arsenic used for?

According to FDA labeling, Arsenic carries indications including: Relieves diarrhea with weakness * Uses: See symptoms on front panel.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Arsenic?

Arsenic is classified as Unknown Cellular or Molecular Interaction, Decreased DNA Integrity.