Bacillus Subtilis
US-FDASourced from openFDA
GET
/api/v1/drug/bacillus-subtilisIndications
Sourced from openFDA- This remedy is indicated for symptoms associated with skin and lung conditions, stomach and intestinal imbalance, rheumatism symptoms, skin allergies, and other internal conditions according to traditional homeopathic practice.*
Dosage & administration
Sourced from openFDADIRECTIONS: Take 5 drops orally, three times per week.
Warnings & precautions
Sourced from openFDADo not use if the tamper evident strip is broken or removed from the base of the cap.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
47 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Diarrhoea919%
- 2Headache715%
- 3Drug-induced Liver Injury613%
- 4Pyrexia613%
- 5Product Use In Unapproved Indication511%
- 6Vomiting511%
- 7Abdominal Distension48.5%
- 8Abdominal Pain48.5%
- 9Abdominal Pain Upper48.5%
- 10Asthenia48.5%
- 11Blood Alkaline Phosphatase Increased48.5%
- 12Bone Pain48.5%
- 13Constipation48.5%
- 14Covid-1948.5%
- 15Drug Ineffective48.5%
Literature
Recent PubMed references pinned to Bacillus Subtilis as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Membrane binding controls the ATPase cycle and localization of MinD in Bacillus subtilis.eLife · 2026 · Feddersen H, Dyckmans C, Bramkamp M, et al.PMID 42258376DOI 10.7554/eLife.101517
- Characterization of bacteriocin, probiotic attributes and genomic information of Bacillus subtilis S1.World journal of microbiology & biotechnology · 2026 · Jain PM, Vinaitheerthan L, Kalathil A, et al.PMID 42257812DOI 10.1007/s11274-026-05070-1
- The Antidepressant Drug Clomipramine Inhibits the ABC Transporter BmrA.Chembiochem : a European journal of chemical biology · 2026 · Hellmann N, Kersten C, Efferth T, et al.PMID 42252745DOI 10.1002/cbic.202500937
- Development of Bacillus subtilis cell factories for nutraceuticals production.World journal of microbiology & biotechnology · 2026 · Shi K, Shi W, Zeng S, et al.PMID 42250015DOI 10.1007/s11274-026-05068-9
- Early supplementation with live combined Bacillus subtilis and Enterococcus faecium: association with feeding intolerance and gut microbiota composition in antibiotic-exposed preterm infants.Frontiers in cellular and infection microbiology · 2026 · Ye C, Li L, Zhang H, et al.PMID 42239542DOI 10.3389/fcimb.2026.1826157
- Stress-induced ribosome degradation in Bacillus subtilis is mediated by the RNase Y-specificity complex.Nature communications · 2026 · Cornejo FA, Driller K, Ahmed-Begrich R, et al.PMID 42230597DOI 10.1038/s41467-026-73310-x
- Enhanced levansucrase expression in Bacillus subtilis via regulatory element optimization for high-yield lactosucrose production from sucrose and lactose.Bioresource technology · 2026 · He H, Yang Y, Wei Q, et al.PMID 42176820DOI 10.1016/j.biortech.2026.134954
- Engineered Bacillus subtilis secreting piscidin-1/hepcidin enhances resistance against Aeromonas hydrophila in a zebrafish model.Fish & shellfish immunology · 2026 · Zhang KY, Zhang WY, Liu JX, et al.PMID 42176787DOI 10.1016/j.fsi.2026.111447
Clinical trials
The 10 most recently updated of 55 ClinicalTrials.gov registrations naming Bacillus Subtilis as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Oral-Spray Bacillus Spore Probiotic in Preventing and Supporting Treatment of Dental Caries in ChildrenRecruiting · Interventional · 130 enrolled · Anabio R&DNCT07241052updated 2026-06-05
- Bacillus Subtilis in Parkinson's DiseaseCompleted · Interventional · 26 enrolled · University of EdinburghNCT06487975updated 2026-04-08
- Effect of Multispecies Probiotic Supplementation on the Efficacy of Rifaximin α Therapy in Patients With Small Intestinal Bacterial Overgrowth (SIBO): a Randomized Placebo-controlled TrialNot yet recruiting · Phase 4 · Interventional · 100 enrolled · Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i AdministracjiNCT07426705updated 2026-02-23
- Assessing Role of Probiotics in Children Aged 6-36 Months Treated for PneumoniaNot yet recruiting · Interventional · 330 enrolled · Anabio R&DNCT07399717updated 2026-02-10
- To Evaluate the Effect of Bacillus Subtilis Based Product in Gut Health and Immunomodulatory Effect in Healthy Adults.Enrolling by invitation · Interventional · 46 enrolled · Bioagile Therapeutics Pvt. Ltd.NCT07377942updated 2026-01-30
- Oral-Spray Bacillus Spore Probiotics for Periodontal Disease Prevention and Supprotive Treatment in the ElderlyRecruiting · Interventional · 90 enrolled · Anabio R&DNCT07258303updated 2026-01-21
- The Effect of a Multispecies Probiotics on Autism Symptoms in ChildrenRecruiting · Interventional · 110 enrolled · Medical University of WarsawNCT06448767updated 2026-01-08
- Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered NeonatesNot yet recruiting · Interventional · 180 enrolled · Anabio R&DNCT07320287updated 2026-01-07
- Probiotic and Ginger Supplement for Symptoms and Quality of Life in Functional Dyspepsia (SUBTILE)Recruiting · Interventional · 198 enrolled · BiocodexNCT07212907updated 2026-01-07
- Preliminary Clinical Study on the Effect of Bacillus Subtilis on the Efficacy of Infliximab in Patients With Crohn's DiseaseRecruiting · Interventional · 24 enrolled · The Third Xiangya Hospital of Central South UniversityNCT07123207updated 2025-08-14
Frequently asked questions
- What is Bacillus Subtilis used for?
- According to FDA labeling, Bacillus Subtilis carries indications including: This remedy is indicated for symptoms associated with skin and lung conditions, stomach and intestinal imbalance, rheumatism symptoms, skin allergies, and other internal conditions according to traditional homeopathic practice.*. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
Note. Data for
bacillus-subtilis is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.