Biotin

Mechanism-of-action class: Enzyme Interactions.

• Uses DirectionsApply twice daily. Shakewell and spray 4-5 times(approx.1 ml) directly ontothe scalp, targeting thinningareas.

Dosage & administration Recommended: it is recommended to use thisproduct on dry hair once or twice daily.

For external use only.

• Feb 21, 2001NDANDA021265Sandoz Canada Inc
• Apr 9, 2026ANDAANDA210273Apotex
• Apr 9, 2026ANDAANDA210672Apotex

Recent PubMed references pinned to Biotin as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Exploring the Link Between Biotin Metabolism and Brucella Virulence: A Study on BioA.
  Pathogens (Basel, Switzerland) · 2026 · Liu D, Quan H, Liu M, et al.
  PMID 42198600DOI 10.3390/pathogens15050473
• Simultaneous multi-biomarker detection: streptavidin-biotin mediated high-quality quantum dot immunosensor with signal amplification.
  Analytica chimica acta · 2026 · Xing H, Zhang R, Li N, et al.
  PMID 42191297DOI 10.1016/j.aca.2026.345589
• Development of a Light-Triggered Biotin-Bioorthogonal System for Targeted Anti-Tumor Therapy.
  Journal of medicinal chemistry · 2026 · Pan Y, Tang C, Zeng Z, et al.
  PMID 42187134DOI 10.1021/acs.jmedchem.6c00794
• Optimizing acid type and pH for dissociation of biotin-labeled drug from streptavidin-coated bead in BEAD ADA assays.
  Bioanalysis · 2026 · Guo L, Jiang Y, Ehlinger C, et al.
  PMID 42152800DOI 10.1080/17576180.2026.2672458
• Design, Synthesis and Biological Evaluation of Potent Piperazine-Based BioA Inhibitors Targeting Biotin Biosynthesis in Mycobacterium tuberculosis.
  Journal of medicinal chemistry · 2026 · Liu Q, Engelhart CA, Wallach JB, et al.
  PMID 42017700DOI 10.1021/acs.jmedchem.5c03325
• Biotin-Decorated Inulin-Based Polymeric Micelles Unveil Their Dual-Targeting Ability for the Potential Treatment of Glioblastoma Multiforme through the In Vitro and In Vivo Investigations.
  Molecular pharmaceutics · 2026 · Riccobelli P, Cannone E, Filiberti S, et al.
  PMID 41973041DOI 10.1021/acs.molpharmaceut.5c01861
• Early Stage of Biotin Biosynthesis Pathway: Non-Conserved Yet Unique.
  Journal of basic microbiology · 2026 · Singh S
  PMID 41943454DOI 10.1002/jobm.70166
• Impact of spacer chain length on self-assembly of paclitaxel-biotin conjugates.
  Journal of pharmaceutical sciences · 2026 · Beigulenko DV, Zhezher IV, Kazakova ES, et al.
  PMID 41895687DOI 10.1016/j.xphs.2026.104263

The 10 most recently updated of 120 ClinicalTrials.gov registrations naming Biotin as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Evaluation of Serum Follistatin-Like Protein 1 Levels in Behcet's Disease and Its Association With Disease Activity
  Completed · Observational · 80 enrolled · Assiut University
  NCT06730958updated 2026-06-10
• Alpha/Beta T-cell Depleted Blood-forming Stem Cell Transplant From Related or Unrelated Donors for Blood Diseases in Children and Young Adults
  Not yet recruiting · Phase 1 · Interventional · 12 enrolled · University of Wisconsin, Madison
  NCT04806347updated 2026-05-26
• Biotin-RBC Transfusion in SCD
  Completed · Phase 1 · Interventional · 22 enrolled · Marianne Yee
  NCT04426591updated 2026-05-22
• Vitamin B Complex for Inferior Alveolar Nerve Paresthesia Recovery
  Not yet recruiting · Phase 4 · Interventional · 50 enrolled · University of Sao Paulo
  NCT07592897updated 2026-05-20
• Use of Ritual Prenatal Multivitamins for Pregnancy
  Completed · Interventional · 80 enrolled · City University of New York
  NCT05673070updated 2026-05-19
• The Acute Interference of Biotin in Blood Analysis
  Recruiting · Interventional · 24 enrolled · University of Copenhagen
  NCT07302880updated 2026-05-06
• Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML
  Recruiting · Phase 1 · Phase 2 · Interventional · 68 enrolled · Washington University School of Medicine
  NCT06158828updated 2026-05-05
• Efficacy and Safety of Millet Seed Extract in Telogen Effluvium Treatment
  Completed · Interventional · 60 enrolled · Kasr El Aini Hospital
  NCT07348120updated 2026-05-05
• The Critical Link Between Gut Microbiome Dysfunction, Cravings and Relapse: RECLAIM-GUT TRIAL
  Active not recruiting · Interventional · 20 enrolled · University of Roehampton
  NCT07350538updated 2026-05-04
• The Primary Purpose of This Study is to Determine if Biotin, Vitamin B7 is an Effective Way to Label Platelets in Survival and Recovery Studies.
  Recruiting · Phase 1 · Interventional · 12 enrolled · Bloodworks
  NCT07513532updated 2026-04-30

Frequently asked questions

How does Biotin work?

Mechanism-of-action class: Enzyme Interactions.

What is Biotin used for?

According to FDA labeling, Biotin carries indications including: Uses DirectionsApply twice daily. Shakewell and spray 4-5 times(approx.1 ml) directly ontothe scalp, targeting thinningareas.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Biotin?

Biotin is classified as Other plain vitamin preparations, Enzyme Interactions, Cellular Activity Alteration.

What are the brand names for Biotin?

Biotin is marketed under brand names including Appearex, Concept OB, Dialyvite 800, Dialyvite 800 with Iron, Dialyvite 800 with Zinc, Hemax, Infuvite, Infuvite Pediatric.