Brompheniramine

Mechanism-of-action classes: Histamine H1 Receptor Antagonists; Monoamine Oxidase Inhibitors.

• Uses temporarily relieves: runny nose sneezing itchy, watery eyes due to hay fever itching of the nose or throat

Directions do not take more than 6 doses in any 24-hour period measure only with dosage cup provided keep dosage cup with product ml = milliliter age Dose adults and children 12 years and over 20 ml every 4 hours children 6 to under 12 years 10 ml every 4 hours children under 6 years do not use

Do not use to sedate a child or to make a child sleepy Ask a doctor before use if you have trouble urinating due to an enlarged prostate gland glaucoma a breathing problem such as emphysema, or chronic bronchitis. Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product do not use more than directed drowsiness may occur avoid alcoholic drinks alcohol, sedatives, and tranquilizers may increase drowsiness be careful when driving a motor vehicle or operating machinery excitability may occur, especially in children If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away at 1-800-222-1222.

• Jul 15, 2014ANDAANDA205292Padagis Us
• Jul 21, 2014ANDAANDA202940Pharm Assoc
• Sep 20, 2016ANDAANDA203375Acella
• Dec 4, 2018ANDAANDA207676Dr Reddys Labs Sa
• Apr 17, 2020ANDAANDA213125Chartwell Molecular
• Jun 16, 2020ANDAANDA211170Hibrow Hlthcare
• Jul 14, 2020ANDAANDA210647Alkem Labs Ltd
• Sep 30, 2020ANDAANDA203997Bionpharma

Recent PubMed references pinned to Brompheniramine as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Bioavailability assessment of a brompheniramine taste-masked pediatric formulation in a juvenile porcine model.
  Biomedical chromatography : BMC · 2024 · Wang J, Shakleya D, Giacoia G, et al.
  PMID 38412513DOI 10.1002/bmc.5845
• Subcutaneous brompheniramine for cutaneous analgesia in rats.
  European journal of pharmacology · 2019 · Chiu CC, Chen JY, Chen YW, et al.
  PMID 31319069DOI 10.1016/j.ejphar.2019.172544
• Determination of brompheniramine enantiomers in rat plasma by cation-selective exhaustive injection and sweeping cyclodextrin modified electrokinetic chromatography method.
  Electrophoresis · 2018 · Yao Y, Zhao Y, Zhang X, et al.
  PMID 29756294DOI 10.1002/elps.201800138
• Brompheniramine and Chlorpheniramine Pharmacokinetics Following Single-Dose Oral Administration in Children Aged 2 to 17 Years.
  Journal of clinical pharmacology · 2018 · Pathirana S, Jayawardena S, Meeves S, et al.
  PMID 29136286DOI 10.1002/jcph.1037
• Reduction of interferences in the analysis of Children's Dimetapp using ultraviolet spectroscopy data and target factor analysis.
  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2018 · Msimanga HZ, Lam TTH, Latinwo N, et al.
  PMID 29128750DOI 10.1016/j.saa.2017.11.012
• Brompheniramine as a novel probe for indirect UV detection and its application for the capillary electrophoresis of adamantane drugs.
  Journal of separation science · 2017 · Prapatpong P, Prutthiwanasan B, Nuchtavorn N, et al.
  PMID 28087893DOI 10.1002/jssc.201601162
• Chiral separation of brompheniramine enantiomers by recycling high-speed countercurrent chromatography using carboxymethyl-β-cyclodextrin as a chiral selector.
  Journal of separation science · 2016 · Zhang P, Xie X, Tang K, et al.
  PMID 27080368DOI 10.1002/jssc.201501240
• Divergence and convergence of commercial and scientific priorities in drug development: The case of Zelmid, the first SSRI antidepressant.
  Social science & medicine (1982) · 2015 · Mulinari S
  PMID 26123880DOI 10.1016/j.socscimed.2015.06.020

The 4 most recently updated of 4 ClinicalTrials.gov registrations naming Brompheniramine as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Study Evaluating Brompheniramine Maleate Liquid in Children and Adolescents
  Completed · Phase 1 · Interventional · 37 enrolled · Wyeth is now a wholly owned subsidiary of Pfizer
  NCT00894634updated 2020-10-23
• Efficacy and Safety of Combination of Brompheniramine and Phenylephrine for the Symptoms Relief of Rhinitis
  Completed · Phase 3 · Interventional · 879 enrolled · Ache Laboratorios Farmaceuticos S.A.
  NCT01393548updated 2017-01-13
• Efficacy and Safety of Combination of Brompheniramine and Phenylephrine for the Symptoms Relief of Rhinitis
  Completed · Phase 3 · Interventional · 167 enrolled · Ache Laboratorios Farmaceuticos S.A.
  NCT01393561updated 2016-10-31
• Evaluation of Efficacy and Safety in Control Cough and the Relief of Nasal Symptoms in Children 2-12 Years Old,Suffering From Cough and Acute Rhinitis
  Withdrawn · Phase 3 · Interventional · 0 enrolled · Ache Laboratorios Farmaceuticos S.A.
  NCT01177852updated 2016-10-19

Frequently asked questions

How does Brompheniramine work?

Mechanism-of-action classes: Histamine H1 Receptor Antagonists; Monoamine Oxidase Inhibitors.

What is Brompheniramine used for?

According to FDA labeling, Brompheniramine carries indications including: Uses temporarily relieves: runny nose sneezing itchy, watery eyes due to hay fever itching of the nose or throat. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Brompheniramine?

Brompheniramine is classified as Substituted alkylamines, Histamine H1 Receptor Antagonists, Monoamine Oxidase Inhibitors, Decreased Acetylcholine Activity, Decreased Histamine Activity.

What are the brand names for Brompheniramine?

Brompheniramine is marketed under brand names including Bromfed DM, BroveX CB, Brovex PBC, M-End PE, Mar-cof BP, Respa-BR.