Calcium Carbonate
GET
/api/v1/drug/calcium-carbonateMechanism of action
Sourced from openFDAMechanism-of-action classes: Acid-Base Activity; Electrolyte Activity.
Indications
Sourced from openFDA- Uses relieves acid indigestion heartburn sour stomach upset stomach associated with these symptoms
Dosage & administration
Sourced from openFDADirections take one to four tablets daily. do not take more than 4 tablets in 24 hours do not use the maximum dosage for more than 2 weeks
Warnings & precautions
Sourced from openFDAAsk a doctor or pharmacist before use if you are taking a prescription drug. Antacids may interact with certain prescription drugs. Stop use and ask a doctor if symptoms last more than 2 weeks. If pregnant or breast-feeding, ask a health professional before use.
Approval history
Sourced from openFDA- Oct 16, 2000NDANDA020958Kenvue Brands
- Feb 6, 2008ANDAANDA077355Perrigo R And D
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
72,344 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Fatigue6,7569.3%
- 2Nausea6,2848.7%
- 3Chronic Kidney Disease5,6877.9%
- 4Diarrhoea5,5767.7%
- 5Drug Ineffective5,3707.4%
- 6Pain5,3357.4%
- 7Off Label Use5,2827.3%
- 8Dyspnoea5,0457.0%
- 9Vomiting4,8656.7%
- 10Headache4,6386.4%
- 11Acute Kidney Injury4,1085.7%
- 12Pneumonia4,0225.6%
- 13Arthralgia3,9905.5%
- 14Malaise3,9035.4%
- 15Pyrexia3,6465.0%
Literature
Recent PubMed references pinned to Calcium Carbonate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Atlantic sediments reveal interacting environmental and physiological controls on coccolithophore calcite production.Nature communications · 2026 · González-Lanchas A, Baumann KH, Stoll HM, et al.PMID 42209484DOI 10.1038/s41467-026-73162-5
- Irinotecan-Loaded Vaterite Microspheres for Drug Delivery: Drug Release and Dissolution Kinetics and Mechanism in an Aqueous Solution and Human Serum.Langmuir : the ACS journal of surfaces and colloids · 2026 · Milner MP, Saint HA, Yang JM, et al.PMID 42201847DOI 10.1021/acs.langmuir.6c01242
- Large-scale experimental investigation of biotreated sand column using different grouting pipe configurations.PloS one · 2026 · Wang C, Wei Z, Shi J, et al.PMID 42189816DOI 10.1371/journal.pone.0349797
- Antacid Abuse - A Case of Milk-Alkali Syndrome.Irish medical journal · 2026 · Varghese S, Cinnamond K, Malek B, et al.PMID 42180434
- Quantitative Proteomic Profiling of Pinctada fucata Shell Nacre Defines a Solubility-Based Type Classification of Shell Matrix Proteins.Marine biotechnology (New York, N.Y.) · 2026 · Oshima K, Negishi L, Atsumi T, et al.PMID 42159797DOI 10.1007/s10126-026-10631-4
- Symbiotic bacteria may support calcium carbonate precipitation in the Gulf toadfish.PLoS biology · 2026 · Bonacolta AM, Kravitz T, Mozo R, et al.PMID 42149909DOI 10.1371/journal.pbio.3003764
- Composite scaffolds comprising spherical CaCO(3)-loaded decellularized porcine skin and kelp ECM for hemostasis and wound healing: In vitro and in vivo study.Biomaterials advances · 2026 · Kim NH, Park M, Shanto PC, et al.PMID 42134205DOI 10.1016/j.bioadv.2026.214933
- The Difference of Tibetan Medicine Nanhanhuanshi From Different Producing Areas Based on Multi-Element and C/O/Sr Stable Isotope.Rapid communications in mass spectrometry : RCM · 2026 · Zhuo Y, Liu XPMID 42120338DOI 10.1002/rcm.70099
Clinical trials
The 10 most recently updated of 485 ClinicalTrials.gov registrations naming Calcium Carbonate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)Recruiting · Phase 2 · Interventional · 461 enrolled · National Cancer Institute (NCI)NCT04546399updated 2026-06-12
- Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged LeukemiaRecruiting · Phase 2 · Interventional · 153 enrolled · National Cancer Institute (NCI)NCT06317662updated 2026-06-11
- Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More TreatmentNot yet recruiting · Phase 2 · Interventional · 90 enrolled · SWOG Cancer Research NetworkNCT07636564updated 2026-06-09
- Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic LeukemiaRecruiting · Phase 2 · Interventional · 80 enrolled · Children's Oncology GroupNCT02981628updated 2026-06-05
- The Impact of IntegBasic Physical Fitness Rated Neuromuscular Training Intervention on the of Military PersonnelCompleted · Interventional · 24 enrolled · Yang LiuNCT06663371updated 2026-06-02
- O. Formigenes Colonization in Calcium Oxalate Kidney Stone DiseaseRecruiting · Interventional · 40 enrolled · University of Alabama at BirminghamNCT06330246updated 2026-05-28
- A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese ParticipantsCompleted · Phase 1 · Interventional · 50 enrolled · Eli Lilly and CompanyNCT06186622updated 2026-05-22
- A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking SurgeryRecruiting · Phase 2 · Interventional · 114 enrolled · Oncoinvent Solutions ASNCT06504147updated 2026-05-20
- COMPARISON OF THE EFFICACY BETWEEN PREOPERATIVE CALCIUM & VITAMIN D3 VERSUS CALCIUM SUPPLEMENTATION ALONE TO PREVENT POST OPERATIVE SYMPTOMATIC HYPOCALCEMIA AFTER TOTAL THYROIDECTOMY IN EUTHYROID PATIENTSNot yet recruiting · Interventional · 124 enrolled · King Edward Medical UniversityNCT07597096updated 2026-05-19
- Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Events in Participants With Type 2 DiabetesCompleted · Observational · 70,000 enrolled · Brigham and Women's HospitalNCT06779929updated 2026-05-15
Frequently asked questions
- How does Calcium Carbonate work?
- Mechanism-of-action classes: Acid-Base Activity; Electrolyte Activity.
- What is Calcium Carbonate used for?
- According to FDA labeling, Calcium Carbonate carries indications including: Uses relieves acid indigestion heartburn sour stomach upset stomach associated with these symptoms. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Calcium Carbonate?
- Calcium Carbonate is classified as Calcium, Calcium compounds, Acid-Base Activity, Electrolyte Activity, Bone Resorption Alteration, Gastric Acid Alteration, Increased Renal PO4-- Excretion.
- What are the brand names for Calcium Carbonate?
- Calcium Carbonate is marketed under brand names including Alka-Mints, Alkums, Cal Gest, Cal-Quick, Caltrate, Caltrate Plus D, Chooz, D-Cal.
Note. Data for
calcium-carbonate is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.