Chloride Ion

Mechanism-of-action classes: Acid-Base Activity; Electrolyte Activity.

• For temporary relief of occasional anxiety, tension and irritability. These uses are based upon traditional homeopathic practice.

Directions Adults and children over 8: Dissolve one Calm Drops lozenge in mouth. Repeat every half hour as needed.

If symptoms persist more than 7 days or worsen, consult a physician. Keep out of children's reach. In case of overdose, get medical help or contact a poison control center right away. If pregnant or breast-feeding, ask a doctor before use. Do not use if shrink wrap is broken or missing.

1. 1Oropharyngeal Pain1100%
2. 2Product Complaint1100%
3. 3Product Packaging Issue1100%
4. 4Product Use Complaint1100%
5. 5Throat Irritation1100%

Recent PubMed references pinned to Chloride Ion as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• A pericyte chloride clamp mechanism governs capillary control of cerebral blood flow.
  Proceedings of the National Academy of Sciences of the United States of America · 2026 · Xiang L, Hariharan A, Isaacs D, et al.
  PMID 42258716DOI 10.1073/pnas.2523612123
• A randomized controlled clinical evaluation of anti-gingivitis and desensitizing efficacy of a newly developed toothpaste with zinc chloride and oriental herb extract.
  American journal of dentistry · 2026 · Moon KT, Lim JH, Oh K, et al.
  PMID 42247364
• 3D-printed solid-contact chloride sensor for sweat-based cystic fibrosis screening.
  Biosensors & bioelectronics · 2026 · Farahani S, Hille NH, Sireesha P, et al.
  PMID 42208308DOI 10.1016/j.bios.2026.118831
• KOH activation of carbon electrodes for enhanced capacitive dechlorination: Performance and mechanisms.
  PloS one · 2026 · Jia J, Lu C, Han J, et al.
  PMID 42201910DOI 10.1371/journal.pone.0347780
• Integrated hydrochemical and health-risk assessment of fluoride and major ions in groundwater from hattar and gadoon industrial estates, pakistan.
  Environmental geochemistry and health · 2026 · Ahmad T, Qadir A, Khan MA, et al.
  PMID 42201498DOI 10.1007/s10653-026-03261-1
• Perioperative hyperchloremia is associated with acute kidney injury in elderly patients undergoing bipolar plasmakinetic transurethral resection of the prostate: a prospective observational study.
  World journal of urology · 2026 · Jia H, Zheng Q, Zhang L, et al.
  PMID 42189243DOI 10.1007/s00345-026-06503-0
• The removal effects and mechanism of sulfate from acid mine drainage using fly ash and sunflower heads composite biochar.
  Environmental geochemistry and health · 2026 · Qian J, Zhou L, Zhang J, et al.
  PMID 42184080DOI 10.1007/s10653-026-03255-z
• Synergistic Electrochemical Characterization of PVC-Based Ni-Co-Mn Phosphate Hybrid Matrix Through Conducting (1:1) Electrolytes for Ion-Exchange Separation and Wastewater Treatment.
  Water environment research : a research publication of the Water Environment Federation · 2026 · Subhan Z, Rashid I, Khan MMA, et al.
  PMID 42159235DOI 10.1002/wer.70410

The 10 most recently updated of 6,577 ClinicalTrials.gov registrations naming Chloride Ion as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung
  Recruiting · Phase 2 · Phase 3 · Interventional · 189 enrolled · National Cancer Institute (NCI)
  NCT05058651updated 2026-06-12
• A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
  Recruiting · Phase 2 · Phase 3 · Interventional · 1,122 enrolled · National Cancer Institute (NCI)
  NCT05691478updated 2026-06-12
• A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)
  Recruiting · Phase 2 · Interventional · 50 enrolled · National Cancer Institute (NCI)
  NCT06064097updated 2026-06-12
• Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
  Recruiting · Phase 3 · Interventional · 1,210 enrolled · National Cancer Institute (NCI)
  NCT04267848updated 2026-06-12
• Testing the Addition of Cemiplimab (REGN2810) to Chemotherapy Treatment Given Prior to Surgery in Patients With Sinonasal Squamous Cell Carcinoma
  Recruiting · Phase 2 · Interventional · 108 enrolled · National Cancer Institute (NCI)
  NCT07281417updated 2026-06-12
• Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer
  Recruiting · Phase 2 · Phase 3 · Interventional · 613 enrolled · National Cancer Institute (NCI)
  NCT01810913updated 2026-06-12
• First-in-Human PfSPZ-LARC2 Vaccination/CHMI
  Active not recruiting · Phase 1 · Interventional · 22 enrolled · National Institute of Allergy and Infectious Diseases (NIAID)
  NCT06735209updated 2026-06-12
• Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
  Recruiting · Phase 3 · Interventional · 478 enrolled · National Cancer Institute (NCI)
  NCT06172296updated 2026-06-12
• A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
  Recruiting · Phase 2 · Phase 3 · Interventional · 2,250 enrolled · Global Coalition for Adaptive Research
  NCT03970447updated 2026-06-12
• Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)
  Suspended · Phase 1 · Interventional · 400 enrolled · National Institute of Allergy and Infectious Diseases (NIAID)
  NCT05652504updated 2026-06-12

Frequently asked questions

How does Chloride Ion work?

Mechanism-of-action classes: Acid-Base Activity; Electrolyte Activity.

What is Chloride Ion used for?

According to FDA labeling, Chloride Ion carries indications including: For temporary relief of occasional anxiety, tension and irritability. These uses are based upon traditional homeopathic practice.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Chloride Ion?

Chloride Ion is classified as Acid-Base Activity, Electrolyte Activity, Cellular Activity Alteration.