Chlorogenic Acid

• For the temporary relief of irritated skin, itching, congestion, hay fever, or occasional headache due to sensitivity to phenolic compounds found in foods or other products.*ICD-10: R51.9

DIRECTIONS Place drops under tongue 30 minutes before/after meals. Adults and children 12 years and over: Take 10 drops up to 3 times per day. Consult a physician for use in children under 12 years of age.

In case of overdose, get medical help or contact a poison control center right away. Keep out of the reach of children. If pregnant or breastfeeding, ask a healthcare professional before use.

1. 1Asthenopia1100%
2. 2Blood Thyroid Stimulating Hormone Increased1100%
3. 3Constipation1100%
4. 4Dry Skin1100%
5. 5Onychoclasis1100%
6. 6Rash1100%

Recent PubMed references pinned to Chlorogenic Acid as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Chlorogenic acid modulates configuration-dependent structural organization, lipid oxidation, and digestion in aqueous starch-unsaturated fatty acid systems.
  Food research international (Ottawa, Ont.) · 2026 · Wen H, Xiang X, Zheng B, et al.
  PMID 42169341DOI 10.1016/j.foodres.2026.119388
• Enhanced preservation of grass carp (Ctenopharyngodon idellus) fillets by chlorogenic acid-chitosan conjugate: mechanisms involving quality retention and targeted microbial suppression.
  Food research international (Ottawa, Ont.) · 2026 · Du H, Duan T
  PMID 42169276DOI 10.1016/j.foodres.2026.119311
• Chlorogenic acids and caffeine in commercial green coffee bean extract supplements: quantitative assessment and evidence of mislabelling.
  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment · 2026 · Otaif KD, Adawi HA, Alfaifi FM, et al.
  PMID 42154619DOI 10.1080/19440049.2026.2655426
• Simple colorimetric monitoring of chlorogenic acid in coffee washing water using Ag-modified faujasite zeolite.
  Environmental monitoring and assessment · 2026 · Malafatti JOD, Paris EC, Mattoso LHC, et al.
  PMID 42126488DOI 10.1007/s10661-026-15430-x
• Chlorogenic acid-ZnO nanocomposite derived from Hydrocotyle javanica Thunb. activates ferroptosis-regulated cell death axis in breast cancer cells.
  Nanomedicine : nanotechnology, biology, and medicine · 2026 · Bellai A, Dutta S, Tag H, et al.
  PMID 42119635DOI 10.1016/j.nano.2026.102953
• A ratiometric fluorescent platform based on nitrogen-doped carbon dots for simultaneous detection and discrimination of chloramphenicol and chlorogenic acid.
  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2026 · Peng S, Zhang Y, Xiao W, et al.
  PMID 42107312DOI 10.1016/j.saa.2026.128043
• Delivery technologies for chlorogenic acid: A comprehensive review of carrier platforms, performance, and challenges.
  Food research international (Ottawa, Ont.) · 2026 · Hu S, Zhao R, Yang S, et al.
  PMID 42083220DOI 10.1016/j.foodres.2026.119179
• Antioxidant Activity of Chlorogenic Acid Evaluated via EPR Spectroscopy and Its Visual Tracking in Mouse Kidney.
  Nutrients · 2026 · Quan L, Li C, Shen P, et al.
  PMID 42074995DOI 10.3390/nu18081181

The 10 most recently updated of 33 ClinicalTrials.gov registrations naming Chlorogenic Acid as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Effects of Polyphenol Supplementation and Exercise on Physical Performance in Older Adults
  Recruiting · Interventional · 40 enrolled · Dr. Chris McGlory, PhD
  NCT07441343updated 2026-02-27
• Resistant Starch, Epigallocatechin Gallate and Chlorogenic Acid for Body Weight Loss in Menopause
  Terminated · Interventional · 144 enrolled · Fondazione IRCCS Policlinico San Matteo di Pavia
  NCT02887950updated 2025-05-01
• Berberine, Chlorogenic Acid and Tocotrienols in Menopause-associated Dyslipidemia
  Completed · Interventional · 63 enrolled · Fondazione IRCCS Policlinico San Matteo di Pavia
  NCT03019263updated 2025-05-01
• Coffee Bioequivalence Trial
  Not yet recruiting · Interventional · 16 enrolled · University of Reading
  NCT06758531updated 2025-01-03
• Can Consumption of an Aronia-mixture Prevent Urinary Tract Infections in Female Patients?
  Completed · Interventional · 23 enrolled · University of Agder
  NCT06618768updated 2024-10-01
• The Effect of Green Coffee Extract on Blood Glucose Homeostasis in Healthy Adults
  Completed · Interventional · 20 enrolled · Dr. Chris McGlory, PhD
  NCT06137066updated 2024-05-10
• Effect of Apple Polyphenols on Vascular Oxidative Stress and Endothelium Function Study (APP trial_2016)
  Completed · Interventional · 62 enrolled · University of Bologna
  NCT03053986updated 2024-02-01
• Guayusa Extract on Exercise Training
  Completed · Interventional · 57 enrolled · Nathaniel Jenkins
  NCT05820399updated 2023-04-19
• Impact of Coffeeberry Extract on Skill Performance During Simulated Match Play in Academy Football Players
  Completed · Interventional · 15 enrolled · PepsiCo Global R&D
  NCT05547204updated 2023-03-16
• Dietary Polyphenols and Glycation in Renal Insufficiency
  Terminated · Interventional · 9 enrolled · NHS Greater Glasgow and Clyde
  NCT02524938updated 2023-02-10

Frequently asked questions

What is Chlorogenic Acid used for?

According to FDA labeling, Chlorogenic Acid carries indications including: For the temporary relief of irritated skin, itching, congestion, hay fever, or occasional headache due to sensitivity to phenolic compounds found in foods or other products.*. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.