Chloroxylenol

Mechanism-of-action class: Physiochemical Activity.

• Drug Facts Box OTC-Indications & Usage Section for hand-washing to decrease bacteria on the skin

Drug Facts Box OTC-Dosage & Administration Section wet hands and forearms apply 5 milliliters (teaspoonful) or palmful to hands and forearms scrub thoroughly for 1 minute and rinse

Drug Facts Box OTC-Warnings Section For external use only

1. 1Drug Ineffective1413%
2. 2Nausea98.5%
3. 3Vomiting98.5%
4. 4Pain87.5%
5. 5Erythema76.6%
6. 6Malaise76.6%
7. 7Renal Failure76.6%
8. 8Weight Decreased76.6%
9. 9Feeling Abnormal65.7%
10. 10Inappropriate Schedule Of Product Administration65.7%
11. 11Acute Kidney Injury54.7%
12. 12Chronic Kidney Disease54.7%
13. 13Decreased Appetite54.7%
14. 14Fatigue54.7%
15. 15Weight Increased54.7%

The 9 most recently updated of 9 ClinicalTrials.gov registrations naming Chloroxylenol as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Omega-3 Supplementation vs Demodex vs Eyelid Cleanser for Pediatric Chalazia
  Not yet recruiting · Phase 2 · Interventional · 168 enrolled · Jaeb Center for Health Research
  NCT07496515updated 2026-03-27
• Effectiveness of Low Level Light Therapy and Intense Pulse Light on Mite Count as Adjuntive Therapies in Demodex Blepharitis Using Artificial Intelligent Program (Ai-Demodex)
  Enrolling by invitation · Interventional · 88 enrolled · Chulalongkorn University
  NCT07169461updated 2025-09-11
• Morphological Analysis of Meibomian Glands
  Unknown · Interventional · 180 enrolled · Zhongshan Ophthalmic Center, Sun Yat-sen University
  NCT04052841updated 2023-04-25
• Hypochlorous Acid Disinfection Prior to Cataract Surgery
  Completed · Phase 3 · Interventional · 54 enrolled · Loma Linda University
  NCT04568213updated 2023-02-21
• Evaluation of SUMMIT BRUSH in Treatment of Blepharitis
  Recruiting · Interventional · 60 enrolled · University of Notre Dame
  NCT04603222updated 2020-11-27
• Particulate Matter, Blood Pressure, and the Sympathetic Nervous System
  Completed · Interventional · 50 enrolled · University of Michigan
  NCT03079843updated 2019-05-02
• Impact of Preoperative Bathing on Post Caesarean Section Surgical Site Infection
  Completed · Interventional · 96 enrolled · Mbarara University of Science and Technology
  NCT03544710updated 2018-06-04
• Effectiveness of Preoperative Surgical Scrubbing Using Clorhexidine Digluconate and Parachlorometaxylenol (ECP)
  Completed · Interventional · 30 enrolled · Ricardo Becerro de Bengoa Vallejo
  NCT02500758updated 2017-05-31
• Randomized Controlled Trial of Long-term Treatment Effectiveness for Meibomian Gland Dysfunction (MGD) and Dry Eye
  Completed · Interventional · 200 enrolled · TearScience, Inc.
  NCT01521507updated 2015-02-23

Frequently asked questions

How does Chloroxylenol work?

Mechanism-of-action class: Physiochemical Activity.

What is Chloroxylenol used for?

According to FDA labeling, Chloroxylenol carries indications including: Drug Facts Box OTC-Indications & Usage Section for hand-washing to decrease bacteria on the skin. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Chloroxylenol?

Chloroxylenol is classified as Phenol and derivatives, Physiochemical Activity, Decreased Cell Wall Integrity.

What are the brand names for Chloroxylenol?

Chloroxylenol is marketed under brand names including Absorbine Veterinary Liniment, Cortane-B, Digiclean E Foam, Foille, Hooflex, Micrell, Ocusoft, Perigiene.