Coenzyme A
/api/v1/drug/coenzyme-aIndications
Sourced from openFDA- Directions: Turn tube upside down and rotate cap to release pellets into cap. Unscrew cap and without touching pellets tip them into the mouth under the tongue.
Dosage & administration
Sourced from openFDADIRECTIONS Take 15 minutes before meals Adults and children 12 years and older 5 pellets 3 times per day Children between 12 years and 6 years of age 3 pellets 3 times per day Children under 6 years 1 pellet 3 times per day to be dissolved into a little water
Warnings & precautions
Sourced from openFDAStop use and ask doctor if symptoms persist more than 5 days or worsen. If pregnant or breast-feeding ask a health professional before use. Keep out of reach of children.
FAERS reports
- 1Abdominal Distension229%
- 2Gait Disturbance229%
- 3Hepatocellular Carcinoma229%
- 4Myalgia229%
- 5Product Dose Omission229%
- 6Anaphylactic Reaction114%
- 7Anxiety114%
- 8Arrhythmia114%
- 9Arthralgia114%
- 10Arthropathy114%
- 11Body Temperature Increased114%
- 12Condition Aggravated114%
- 13Coronary Artery Stenosis114%
- 14Covid-19114%
- 15Dehydration114%
Literature
Recent PubMed references pinned to Coenzyme A as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Engineering an Acyl-CoA Ligase With Enhanced Activity Toward Synthetic CoA Alternatives.Chembiochem : a European journal of chemical biology · 2026 · Cossin JR, Taboada SA, Williams GJ, et al.PMID 42124487DOI 10.1002/cbic.70385
- MESH1-mediated coenzyme A degradation drives ferroptosis sensitivity and muscle pathology.The Journal of clinical investigation · 2026 · Lin CC, Rose J, Mestre AA, et al.PMID 42033660DOI 10.1172/JCI202212
- AcuB senses cellular energy charge to coordinate acetyl-CoA synthesis in bacteria.Nature communications · 2026 · Janetzky M, Geist N, Schulze S, et al.PMID 42031755DOI 10.1038/s41467-026-71006-w
- Lysine Propionylation as a Metabolically Coupled PTM: Mechanisms, Functional Consequences, and Therapeutic Potentials.International journal of molecular sciences · 2026 · Liu Z, Wang X, Li L, et al.PMID 41977129DOI 10.3390/ijms27072937
- Metabolic adaptations of hemoparasites: coenzyme A and polyamine biosynthesis pathways as drug targets.Current opinion in microbiology · 2026 · Singh P, Obi P, Ben Mamoun C, et al.PMID 41967290DOI 10.1016/j.mib.2026.102753
- Cytosolic AcCoA: a metabolic signal bridging nutrient sensing and mitophagy.Trends in biochemical sciences · 2026 · Chen J, Pan XPMID 41905847DOI 10.1016/j.tibs.2026.01.007
- SREBP2 links ACSS2-dependent acetyl-CoA biosynthesis to metaboloepigenetic activation of hepatic stellate cells and liver fibrosis.Metabolism: clinical and experimental · 2026 · Wang Y, Kang A, Wang S, et al.PMID 41887397DOI 10.1016/j.metabol.2026.156597
- Engineering of CoA-Acylating Butyraldehyde Dehydrogenase for Enhanced 1,3-Butanediol Production in Escherichia coli.Biotechnology and bioengineering · 2026 · Cho S, Islam T, Islam S, et al.PMID 41882757DOI 10.1002/bit.70197
Clinical trials
The 10 most recently updated of 3,443 ClinicalTrials.gov registrations naming Coenzyme A as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)Recruiting · Phase 2 · Interventional · 461 enrolled · National Cancer Institute (NCI)NCT04546399updated 2026-06-12
- Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)Recruiting · Phase 1 · Phase 2 · Interventional · 298 enrolled · Merck Sharp & Dohme LLCNCT06780111updated 2026-06-12
- Investigation of Medical Management to Prevent Episodes of Diverticulitis TrialCompleted · Interventional · 71 enrolled · University of WashingtonNCT05681559updated 2026-06-12
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening TrialRecruiting · Phase 2 · Interventional · 2,900 enrolled · National Cancer Institute (NCI)NCT05564377updated 2026-06-12
- A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal AdenocarcinomaRecruiting · Phase 2 · Phase 3 · Interventional · 900 enrolled · AbbVieNCT07490301updated 2026-06-12
- BOTOX Injection Technique for LUTS Due to BPHCompleted · Phase 1 · Interventional · 60 enrolled · Benha UniversityNCT07645456updated 2026-06-12
- Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With ObesityNot yet recruiting · Phase 2 · Interventional · 60 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT05713799updated 2026-06-12
- Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural EffusionRecruiting · Early phase 1 · Interventional · 30 enrolled · M.D. Anderson Cancer CenterNCT06184321updated 2026-06-12
- Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated CoagulationNot yet recruiting · Phase 4 · Interventional · 40 enrolled · NYU Langone HealthNCT07644923updated 2026-06-12
- Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal CancerActive not recruiting · Phase 2 · Interventional · 8 enrolled · H. Lee Moffitt Cancer Center and Research InstituteNCT06109467updated 2026-06-12
Frequently asked questions
- What is Coenzyme A used for?
- According to FDA labeling, Coenzyme A carries indications including: Directions: Turn tube upside down and rotate cap to release pellets into cap. Unscrew cap and without touching pellets tip them into the mouth under the tongue.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
coenzyme-a is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.