Coumarin

• For the temporary relief of bloating, gas, fatigue, occasional headache, hay fever, or minor lower back or neck pain due to sensitivity to phenolic compounds found in foods or other products.*ICD-10: R51.9

DIRECTIONS Place drops under tongue 30 minutes before/after meals. Adults and children 12 years and over: Take 10 drops up to 3 times per day. Consult a physician for use in children under 12 years of age.

In case of overdose, get medical help or contact a poison control center right away. Keep out of the reach of children. If pregnant or breastfeeding, ask a healthcare professional before use.

1. 1Drug Ineffective159.2%
2. 2Hyponatraemia148.6%
3. 3Atrial Fibrillation138.0%
4. 4Asthenia116.7%
5. 5Acute Kidney Injury106.1%
6. 6Cerebrovascular Accident106.1%
7. 7Rash106.1%
8. 8Renal Impairment106.1%
9. 9Blood Creatinine Increased95.5%
10. 10Fall95.5%
11. 11Fatigue95.5%
12. 12Off Label Use95.5%
13. 13Pain In Extremity95.5%
14. 14Dyspnoea84.9%
15. 15Pyrexia84.9%

The 10 most recently updated of 14 ClinicalTrials.gov registrations naming Coumarin as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Efficacy and Safety of a Botanical Total Coumarin (TC) Cream in Treating Patients With Psoriasis Vulgaris (PLANTCOAT-IIb Trial)
  Completed · Phase 2 · Interventional · 88 enrolled · Psoriasis Research Institute of Guangzhou
  NCT03372811updated 2026-03-25
• Efficacy and Safety of a Botanical Total Coumarin (TC) Cream in Treating Patients With Psoriasis Vulgaris (PLANTCOAT-III)
  Recruiting · Phase 3 · Interventional · 300 enrolled · Psoriasis Research Institute of Guangzhou
  NCT07426120updated 2026-02-23
• Daphnetin Capsule In the Treatment of VaScular COgnitive Impairment Without Dementia
  Recruiting · Interventional · 206 enrolled · First People's Hospital of Shenyang
  NCT06507488updated 2025-08-28
• Efficacy and Safety of Kui-Yuan Chewable Tablets in Patients With Hyperuricemia
  Unknown · Phase 4 · Interventional · 126 enrolled · Quan Jiang
  NCT05913310updated 2023-06-22
• Effectiveness of a Multidisciplinary Medication Review With Follow-up for Patients Treated With Coumarin Anticoagulants in Primary Care
  Completed · Interventional · 204 enrolled · Universidad San Jorge
  NCT03154489updated 2021-05-04
• D-dimer to Establish Duration of Anticoagulation After Venous Thromboembolism
  Completed · Phase 4 · Interventional · 600 enrolled · IRCCS Azienda Ospedaliero-Universitaria di Bologna
  NCT00264277updated 2021-03-19
• Anticoagulation in Liver Fibrosis in Patients With Hepatitis C Virus Infection
  Completed · Phase 2 · Interventional · 14 enrolled · Imperial College London
  NCT00180674updated 2020-12-01
• Rivaroxaban Compared to Vitamin K Antagonist Upon Development of Cardiovascular Calcification
  Completed · Phase 4 · Interventional · 192 enrolled · RWTH Aachen University
  NCT02066662updated 2020-10-22
• Intracerebral Hemorrhage Due to Oral Anticoagulants: Prediction of the Risk by Magnetic Resonance
  Completed · Observational · 1,000 enrolled · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
  NCT02238470updated 2018-08-03
• Efficacy and Safety of Coumarin and Troxerutin in the Symptomatic Treatment of Chronic Venous Insufficiency
  Completed · Phase 4 · Interventional · 829 enrolled · Takeda
  NCT01848210updated 2016-11-11

Frequently asked questions

What is Coumarin used for?

According to FDA labeling, Coumarin carries indications including: For the temporary relief of bloating, gas, fatigue, occasional headache, hay fever, or minor lower back or neck pain due to sensitivity to phenolic compounds found in foods or other products.*. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.