Dextran
/api/v1/drug/dextranMechanism of action
Sourced from openFDAMechanism-of-action class: Structural Macromolecules.
Indications
Sourced from openFDA- Uses • relieves redness of the eye due to minor eye irritations • as a lubricant to prevent further irritation or to relieve dryness of the eye
Dosage & administration
Sourced from openFDADirections Instill 1 to 2 drops in the affected eye(s) up to 4 times daily. Relabeled By: Preferred Pharmaceuticals Inc. NDC 68788-8635-1
Warnings & precautions
Sourced from openFDAFor external use only Ask a doctor before use if you have narrow angle glaucoma Stop use and ask a doctor if you experience • eye pain • changes in vision • continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours When using this product • pupils may become enlarged temporarily • to avoid contamination, do not touch tip of container to any surface. Replace cap after using. • if solution changed color or becomes cloudy, do not use • overuse may produce increased redness of the eye • remove contact lens before using If pregnant or breast-feeding , ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison control Center (1-800-111-1222) right away.
Approval history
Sourced from openFDA- Apr 29, 1974NDANDA017441Allergan
FAERS reports
- 1Dyspnoea26516%
- 2Infusion Related Reaction1569.2%
- 3Nausea1368.0%
- 4Back Pain1176.9%
- 5Flushing1076.3%
- 6Chest Pain1066.2%
- 7Anaphylactic Reaction1036.0%
- 8Dizziness945.5%
- 9Off Label Use935.5%
- 10Pruritus885.2%
- 11Chest Discomfort804.7%
- 12Hypotension764.5%
- 13Vomiting744.3%
- 14Headache734.3%
- 15Diarrhoea714.2%
Literature
Recent PubMed references pinned to Dextran as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- A PSMA-targeted dextran-based conjugate eradicates PSMA-overexpressing prostate tumors while abolishing cabazitaxel toxicity.Theranostics · 2026 · Yang L, Liu T, Huo M, et al.PMID 42244979DOI 10.7150/thno.124663
- Texture Engineering of Nondairy Yogurt Alternatives: Ingredient Selection, Processing Strategies, and the Role of In Situ Dextrans.Comprehensive reviews in food science and food safety · 2026 · Xu Y, Maina NH, Wang Y, et al.PMID 42212401DOI 10.1111/1541-4337.70517
- Butyrate improves dextran sulfate sodium-induced enterotoxicity in broilers.Molecular immunology · 2026 · Bai X, Li R, Quan T, et al.PMID 42190407DOI 10.1016/j.molimm.2026.04.017
- Hybrid dextran/fibronectin nanogels for brain-targeted mitophagy inducer delivery to alleviate neuroinflammation and neuronal loss of Parkinson's disease.Carbohydrate polymers · 2026 · Qin M, Sun H, Ji Y, et al.PMID 42173608DOI 10.1016/j.carbpol.2026.125410
- Rosmarinic acid-derived micelles potentiated dextran hydrogel for concurrent mechanical reinforcement and inflammatory microenvironment remodeling in chronic diabetic wound healing.Carbohydrate polymers · 2026 · Zhang H, Wang J, Hu H, et al.PMID 42173580DOI 10.1016/j.carbpol.2026.125375
- Comparative Analysis of Intravitreal Diffusion Patterns Across Ex Vivo Human and In Vivo/Ex Vivo Animal Models.Investigative ophthalmology & visual science · 2026 · Ayalon A, Beryozkin A, Davoli KA, et al.PMID 42159438DOI 10.1167/iovs.67.5.56
- Herbal micelles loaded oxidized dextran/gelatin hydrogel with enhanced antibacterial and microenvironment reconstruction capacity for MRSA-infected wound healing.International journal of biological macromolecules · 2026 · Liu F, Shi C, He S, et al.PMID 42155737DOI 10.1016/j.ijbiomac.2026.152595
- Study on HSA and Dex-40 Mitigating Osmotic Damage in NK Cells During CPA Loading.Macromolecular bioscience · 2026 · Lin X, Tang Z, Cui M, et al.PMID 42149568DOI 10.1002/mabi.70196
Clinical trials
The 10 most recently updated of 247 ClinicalTrials.gov registrations naming Dextran as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Anlotinib+Cadonilimab+PULSAR in Advanced Biliary Tract CancerActive not recruiting · Phase 2 · Interventional · 26 enrolled · West China HospitalNCT07635290updated 2026-06-09
- Daily and Weekly Iron Supplementation in InfantsCompleted · Interventional · 287 enrolled · Mahidol UniversityNCT06318858updated 2026-06-01
- PULSAR Combined With Immunotherapy for Unresectable Locally Advanced Gastric CancerRecruiting · Interventional · 53 enrolled · Samsung Medical CenterNCT07607119updated 2026-05-28
- Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm InfantsRecruiting · Phase 2 · Interventional · 120 enrolled · University of WashingtonNCT05340465updated 2026-05-26
- NALIRIFOX+Adebrelimab+PULSAR for Advanced Pancreatic CancerRecruiting · Phase 1 · Phase 2 · Interventional · 55 enrolled · West China HospitalNCT07595172updated 2026-05-19
- Study of PULSAR-ICI +/- IMSA101 in Patients With Oligoprogressive Solid Tumor MalignanciesTerminated · Phase 2 · Interventional · 16 enrolled · ImmuneSensor Therapeutics Inc.NCT05846659updated 2026-05-15
- Pediatric Outcomes and Recovery With Peri-Operative Iron Supplement EvaluationRecruiting · Interventional · 180 enrolled · University of British ColumbiaNCT07095244updated 2026-05-14
- Collagen Crosslinking for Keratoconus - a Randomized Controlled Clinical TrialActive not recruiting · Phase 3 · Interventional · 36 enrolled · Sahlgrenska University HospitalNCT01604135updated 2026-05-11
- Sucrosomial Iron and Iron Sulphate to Blood DonorsCompleted · Interventional · 120 enrolled · Uppsala University HospitalNCT05678647updated 2026-04-29
- Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal MeltingRecruiting · Interventional · 40 enrolled · Centre hospitalier de l'Université de Montréal (CHUM)NCT03041883updated 2026-04-28
Frequently asked questions
- How does Dextran work?
- Mechanism-of-action class: Structural Macromolecules.
- What is Dextran used for?
- According to FDA labeling, Dextran carries indications including: Uses • relieves redness of the eye due to minor eye irritations • as a lubricant to prevent further irritation or to relieve dryness of the eye. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Dextran?
- Dextran is classified as Blood substitutes and plasma protein fractions, Structural Macromolecules, Increased Intravascular Volume.
dextran is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.