Diflorasone

Mechanism-of-action classes: Corticosteroid Hormone Receptor Agonists; Glucocorticoid Receptor Agonists.

• Topical corticosteroids are indicated for relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

• Topical steroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.contraindicated

Diflorasone diacetate ointment should be applied to the affected area as a thin film from one to three times daily depending on the severity or resistant nature of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy initiated.

The following local adverse reactions have been reported with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in approximate decreasing order of occurrence: 1. Burning 2. Itching 3. Irritation 4. Dryness 5. Folliculitis 6. Hypertrichosis 7. Acneiform eruptions 8. Hypopigmentation 9. Perioral dermatitis 10. Allergic contact dermatitis 11. Maceration of the skin 12. Secondary infection 13. Skin atrophy 14. Striae 15. Miliaria To report SUSPECTED ADVERSE REACTIONS, contact Rising Pharmaceuticals, Inc. at 1-844-874-7464 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Pregnancy Category C Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects. (see PRECAUTIONS .)

• May 14, 1999ANDAANDA075331Sun Pharma Canada
• Apr 24, 2000ANDAANDA075508Sun Pharma Canada
• Feb 27, 2017ANDAANDA207440Rising

1. 1Psoriasis168.6%
2. 2Pruritus158.1%
3. 3Nausea147.6%
4. 4Pyrexia147.6%
5. 5Pain126.5%
6. 6Drug Ineffective115.9%
7. 7Vomiting105.4%
8. 8Fatigue94.9%
9. 9Headache94.9%
10. 10Anaemia73.8%
11. 11Anxiety73.8%
12. 12Asthenia73.8%
13. 13Diarrhoea73.8%
14. 14Febrile Neutropenia73.8%
15. 15Rash73.8%

Frequently asked questions

How does Diflorasone work?

Mechanism-of-action classes: Corticosteroid Hormone Receptor Agonists; Glucocorticoid Receptor Agonists.

What is Diflorasone used for?

According to FDA labeling, Diflorasone carries indications including: Topical corticosteroids are indicated for relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Diflorasone?

Diflorasone is classified as Corticosteroids, potent (group III), Corticosteroid, Corticosteroid Hormone Receptor Agonists, Glucocorticoid Receptor Agonists, Antipruritic Activity, Decreased Immunologically Active Molecule Activity, Decreased Protein Synthesis, Vasoconstriction.

What are the brand names for Diflorasone?

Diflorasone is marketed under brand names including Apexicon, Psorcon.

What are the contraindications for Diflorasone?

Diflorasone labeling lists contraindications including: Topical steroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.. Always consult the full prescribing information and a clinician.