Glutathione

• May temporarily relieve symptoms of fatigue.** **Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.

DIRECTIONS: Adults and children 5 to 10 drops orally, 1 time daily or as otherwise directed by a health care professional. If symptoms persist, consult your health care professional. Consult a physician for use in children under 12 years of age.

If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Do not use if tamper evident seal is broken or missing. Store in a cool, dry place.

• Oct 28, 1981NDANDA018469Alcon

1. 1Off Label Use1416.7%
2. 2Endophthalmitis1255.9%
3. 3Nausea1235.8%
4. 4Fatigue1095.2%
5. 5Hepatic Function Abnormal1065.0%
6. 6Platelet Count Decreased974.6%
7. 7Anaemia954.5%
8. 8Headache944.5%
9. 9Diarrhoea924.4%
10. 10Pyrexia884.2%
11. 11Pain833.9%
12. 12White Blood Cell Count Decreased813.8%
13. 13Pneumonia793.7%
14. 14Dizziness773.7%
15. 15Dyspnoea773.7%

Recent PubMed references pinned to Glutathione as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Glutathione depletion under hypoxia via a birnessite-type manganese oxide nanozyme inducing immunogenic ferroptosis for magnetic resonance imaging guided cancer therapy.
  Theranostics · 2026 · Sun H, Li B, Qiu L, et al.
  PMID 42244986DOI 10.7150/thno.129808
• Dl‑3‑n‑Butylphthalide Protects the Blood-Brain Barrier in Neonatal Hypoxic‑Ischemic Brain Damage by Alleviating Endothelial Cell Ferroptosis via the SLC7A11/GSH/GPX4 Pathway.
  Molecular neurobiology · 2026 · Ou J, Yu Q, Luo Y, et al.
  PMID 42240802DOI 10.1007/s12035-026-05974-x
• Controlled Glutathione-Releasing Multifunctional Gelatin Methacryloyl/Chitosan/Zeolite Hydrogels for Accelerated Regeneration in Diabetic Wounds.
  Journal of biomedical materials research. Part A · 2026 · Kabadas FB, Bedir T, Ilhan E, et al.
  PMID 42237728DOI 10.1002/jbm.a.70101
• Dual-ligand Zr-based metal-organic framework probe with turn-on fluorescent response for dual-channel live cell imaging of phosphate and glutathione.
  Mikrochimica acta · 2026 · Wei X, Wang H, Feng X, et al.
  PMID 42237033DOI 10.1007/s00604-026-08104-5
• Overcoming the ''turn-off'' limitation via steric hindrance: A ''turn-on'' dual-readout nanozyme array based on spindle-shaped Prussian blue for highly selective discrimination of glutathione and food additives.
  Analytica chimica acta · 2026 · Li M, Huang T, Liao S, et al.
  PMID 42230019DOI 10.1016/j.aca.2026.345668
• Sensitivity of respiratory cell lines to unsaturated carbonyl compounds in cigarette smoke is regulated by intracellular glutathione.
  The Journal of toxicological sciences · 2026 · Higashi T, Naganuma F, Mai Y, et al.
  PMID 42219359DOI 10.2131/jts.51.357
• Synergistic effects of nanoplastics and BDE-47 on glutathione dysregulation in rice: Insights from integrated multi-omics and computational modeling.
  Journal of environmental sciences (China) · 2026 · Yao Z, Chen J, Gao Z, et al.
  PMID 42217878DOI 10.1016/j.jes.2025.09.005
• Self-assembled micelles stabilized by covalent α-lipoic acid-carboxymethyl chitosan conjugates: Enabling stable delivery and glutathione-responsive release of coenzyme Q10.
  Food research international (Ottawa, Ont.) · 2026 · Liu L, Wang J, Zhao R, et al.
  PMID 42215093DOI 10.1016/j.foodres.2026.119425

The 10 most recently updated of 265 ClinicalTrials.gov registrations naming Glutathione as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Assessment of the Impact of N-acetylcysteine Supplementation on Physical Performance
  Completed · Interventional · 77 enrolled · Poznan University of Life Sciences
  NCT05604586updated 2026-06-10
• To Evaluate the Efficacy and Safety of N-acetyl Cysteine Administration in Patients With Diabetic Retinopathy
  Recruiting · Phase 4 · Interventional · 76 enrolled · Ain Shams University
  NCT07634991updated 2026-06-09
• GABA and GSH in FRDA
  Enrolling by invitation · Observational · 60 enrolled · Children's Hospital of Philadelphia
  NCT07635030updated 2026-06-09
• Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study
  Recruiting · Phase 1 · Phase 2 · Interventional · 100 enrolled · Adia Med of Winter Park LLC
  NCT07304440updated 2026-06-08
• Adia Med of Winter Park LLC Chronic Kidney Disease Research Study
  Recruiting · Phase 1 · Interventional · 100 enrolled · Adia Med of Winter Park LLC
  NCT07572890updated 2026-06-08
• Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supplementation
  Recruiting · Phase 1 · Interventional · 30 enrolled · Pravat Mandal
  NCT07050173updated 2026-06-03
• GAIP ASD Research Study
  Recruiting · Phase 1 · Interventional · 100 enrolled · Greater Atlanta Integrative Pediatrics
  NCT07622316updated 2026-06-03
• SPI-1005 in Adults Receiving Cochlear Implant
  Recruiting · Phase 2 · Interventional · 40 enrolled · Sound Pharmaceuticals, Incorporated
  NCT06340633updated 2026-06-03
• SPI-1005 for the Treatment of Meniere's Disease (Open Label)
  Recruiting · Phase 3 · Interventional · 200 enrolled · Sound Pharmaceuticals, Incorporated
  NCT06859788updated 2026-06-02
• Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease
  Recruiting · Phase 2 · Interventional · 56 enrolled · Gateway Institute for Brain Research
  NCT05266417updated 2026-05-28

Frequently asked questions

What is Glutathione used for?

According to FDA labeling, Glutathione carries indications including: May temporarily relieve symptoms of fatigue.** **Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Glutathione?

Glutathione is classified as Antidotes.