Hyaluronate

• instantly helps relieveanorectal itching and discom-fort such as pain, soreness, orburning commonly associatedwith hemorrhoids temporarily protects theinflamed, irritated anorectalarea to make future bowelmovements less painful fromirritation and abrasion

adults and children 12 yearsof age and over: apply to theaffected area then wash awaywith water and rinse thor-oughly 1-2 times dally orsimply while showering.For intrarectal use: applyaround the affected anal areaand then wash away withwater and rinse thoroughly. children under 12 years ofage: ask a doctor

For external use.

1. 1Keratopathy435.4%
2. 2Diarrhoea415.2%
3. 3Headache354.4%
4. 4Vomiting354.4%
5. 5Nausea344.3%
6. 6Pneumonia303.8%
7. 7Pyrexia293.7%
8. 8Glaucoma263.3%
9. 9Rash263.3%
10. 10Dyspnoea243.0%
11. 11Off Label Use243.0%
12. 12Drug Ineffective222.8%
13. 13Fatigue222.8%
14. 14Retinal Vasculitis222.8%
15. 15Dizziness212.7%

The 10 most recently updated of 418 ClinicalTrials.gov registrations naming Hyaluronate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Clinical Trial to Evaluate the Efficacy and Safety of Conjuran® After First and Second Cycle (Repeat) Administration in Patients With Knee Osteoarthritis
  Not yet recruiting · Interventional · 180 enrolled · PharmaResearch Co.,Ltd
  NCT07646483updated 2026-06-12
• The Effect of Eyelid Support Plate Assisted Eyelid Massage on Meibomian Gland Dysfunction: a Randomized Controlled Trial
  Not yet recruiting · Interventional · 142 enrolled · Zhongshan Ophthalmic Center, Sun Yat-sen University
  NCT07633938updated 2026-06-11
• Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease
  Recruiting · Interventional · 80 enrolled · TRB Chemedica International SA
  NCT05865457updated 2026-06-03
• Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease
  Recruiting · Interventional · 80 enrolled · TRB Chemedica International SA
  NCT05865379updated 2026-06-03
• Effectiveness and Safety of OSTENIL® TENDON in the Treatment of Pain and Restricted Mobility in Tendon Disorders
  Recruiting · Observational · 84 enrolled · TRB Chemedica AG
  NCT06681051updated 2026-06-02
• Study of the Subdermal Implant "Algeness"
  Completed · Interventional · 40 enrolled · Estelab Clinic
  NCT07618468updated 2026-06-01
• To Evaluate the Safety and Effectiveness of Intrauterine Adhesion Preventer in the Prevention and Treatment of Intrauterine Adhesions, a Prospective, Multicenter, Randomized Controlled Clinical Trial
  Recruiting · Interventional · 200 enrolled · The Third Xiangya Hospital of Central South University
  NCT07611474updated 2026-05-28
• A Study Comparing the Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution 0.025% With Sodium Hyaluronate Relative to Lumify in Adult Subjects With Ocular Redness
  Completed · Phase 3 · Interventional · 578 enrolled · Bausch & Lomb Incorporated
  NCT06803654updated 2026-05-28
• Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis
  Recruiting · Phase 3 · Interventional · 300 enrolled · Medipost, Inc.
  NCT07339111updated 2026-05-26
• A Study to Evaluate the Effectiveness and Safety of Restylane Skinboosters Vital Lidocaine
  Recruiting · Interventional · 171 enrolled · Galderma R&D
  NCT07047638updated 2026-05-22

Frequently asked questions

What is Hyaluronate used for?

According to FDA labeling, Hyaluronate carries indications including: instantly helps relieveanorectal itching and discom-fort such as pain, soreness, orburning commonly associatedwith hemorrhoids temporarily protects theinflamed, irritated anorectalarea to make future bowelmovements less painful fromirritation and abrasion. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What are the brand names for Hyaluronate?

Hyaluronate is marketed under brand names including Amvisc, Biolon, Bionect, DisCoVisc, Durolane, Euflexxa, Gel-One, Gel-Syn.