Hydrogen Peroxide

Mechanism-of-action class: Unknown Cellular or Molecular Interaction.

• Uses first aid to help prevent the risk of infection in minor cuts, scrapes and burns aids in the removal of phlegm, mucous, or other secretions associated with occasional sore mouth

Directions First aid antiseptic: clean the affected area apply a small amount of product on the area 1 to 3 times daily may be covered with a sterile bandage if bandaged, let dry first Oral debriding agent (oral rinse): adults and children 2 years of age and over: mix with an equal amount of water swish around in the mouth over the affected area for at least 1 minute and then spit out use up to 4 times daily after meals and at bedtime or as directed by a dentist or doctor children under 12 years of age should be supervised in the use of this product children under 2 years of age: consult a dentist or doctor

For external use only

1. 1Drug Ineffective3712%
2. 2Nausea247.5%
3. 3Fatigue237.2%
4. 4Pruritus175.3%
5. 5Vomiting175.3%
6. 6Headache165.0%
7. 7Rash165.0%
8. 8Product Use In Unapproved Indication154.7%
9. 9Shock Haemorrhagic144.4%
10. 10Dyspnoea134.0%
11. 11Gastritis Erosive134.0%
12. 12Intentional Product Misuse134.0%
13. 13Paraesthesia134.0%
14. 14Pyrexia134.0%
15. 15Toxicity To Various Agents123.7%

Recent PubMed references pinned to Hydrogen Peroxide as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• The possible therapeutic effect of platelet-rich plasma versus its derived exosomes in a hydrogen peroxide-induced depigmentation model in adult guinea pigs: a histological study.
  Journal of molecular histology · 2026 · Hussieny AF, Abounasef SK, Hamam GG, et al.
  PMID 42257913DOI 10.1007/s10735-026-10847-7
• Catalase-like activity of Co(2+)-MOF/CNTs nanocomposite for in situ electrochemical sensing of H(2)O(2) in living cells.
  Mikrochimica acta · 2026 · Zhou Y, Zhu L, Li M, et al.
  PMID 42250020DOI 10.1007/s00604-026-08189-y
• Comparison of Chemiluminescences Induced by Cytochrome C Plus Hydrogen Peroxide Reaction and Zymosan-Induced Phagocytosis in Human Peripheral Phagocytes.
  Luminescence : the journal of biological and chemical luminescence · 2026 · Sipka S, Nagy A, Diós Á, et al.
  PMID 42236147DOI 10.1002/bio.70520
• Suspected venous oxygen embolism following hydrogen peroxide wound irrigation causing intraoperative asystole.
  BMJ case reports · 2026 · Sharafat MA, Khan ZA, Sohaib M, et al.
  PMID 42236105DOI 10.1136/bcr-2025-271477
• Real-time in-situ H(2)O(2) quantification in high-biomass marine environments with a robust NiCo-MOF nanosheet electrode.
  Analytica chimica acta · 2026 · Zhao D, Lu Y, Mao H, et al.
  PMID 42219639DOI 10.1016/j.aca.2026.345658
• Forces Shaping Diversity of Hydrogen Peroxide Detoxification Potential in Ocean Microbial Ecosystems.
  Environmental microbiology · 2026 · Goldberg H, Dyhrman ST, DeMers MA, et al.
  PMID 42208547DOI 10.1111/1462-2920.70315
• Sterilization efficacy of a warm-air circulation system in a vaporized hydrogen peroxide sterilizer.
  PloS one · 2026 · Noh MS, Lee SY, Lee EG, et al.
  PMID 42201912DOI 10.1371/journal.pone.0347533
• H(2)O(2)-Mediated Covalently Cross-Linked Assemblies with Phosphodiesterase-like Activity for Spectral Sensing.
  Langmuir : the ACS journal of surfaces and colloids · 2026 · Li SB, Cai QG, Xu Y, et al.
  PMID 42201681DOI 10.1021/acs.langmuir.6c00619

The 10 most recently updated of 275 ClinicalTrials.gov registrations naming Hydrogen Peroxide as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Electrolytic Surface Decontamination in the Surgical Treatment of Peri-implantitis: A Randomized Clinical Trial
  Not yet recruiting · Interventional · 80 enrolled · Istanbul University
  NCT07644975updated 2026-06-12
• To Evaluate the Efficacy and Safety of N-acetyl Cysteine Administration in Patients With Diabetic Retinopathy
  Recruiting · Phase 4 · Interventional · 76 enrolled · Ain Shams University
  NCT07634991updated 2026-06-09
• Influence of Implant Surface Decontamination on the Reconstructive Outcomes of Peri-implantitis
  Active not recruiting · Interventional · 60 enrolled · Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
  NCT05615051updated 2026-06-08
• Efficacy of an Experimental Gel Based on Libidibia Ferrea on Post-bleaching Tooth Sensitivity
  Not yet recruiting · Interventional · 75 enrolled · Universidade Federal do Para
  NCT07599514updated 2026-05-22
• PICN Versus Bioactive Composite for Cervical Restorations in Ballet Dancers
  Completed · Interventional · 20 enrolled · I.M. Sechenov First Moscow State Medical University
  NCT07598305updated 2026-05-20
• Evaluation of Sensitivity and Color Change of Different Protocols of In-office Dental Bleaching
  Active not recruiting · Interventional · 40 enrolled · Universidade Federal Fluminense
  NCT07597044updated 2026-05-19
• Evaluation of In-office Bleaching-induced Sensitivity With 2 or 7 Days Interval Between Sessions
  Completed · Interventional · 47 enrolled · Universidade Federal Fluminense
  NCT06394557updated 2026-05-15
• A Study Measuring Markers of Airway Inflammation in Breath Samples From People With Respiratory Diseases and Healthy Volunteers.
  Recruiting · Observational · 140 enrolled · Portsmouth Hospitals NHS Trust
  NCT07426718updated 2026-05-08
• Effects of an Experimental Propolis Gel on Tooth Sensitivity Control and Post-bleaching Color Change: a Randomized Clinical Trial
  Not yet recruiting · Interventional · 66 enrolled · Universidade Federal do Para
  NCT07569276updated 2026-05-06
• Contribution of a* to Dental Bleaching After Combined Dental Bleaching
  Not yet recruiting · Interventional · 10 enrolled · University of Valencia
  NCT07560761updated 2026-05-06

Frequently asked questions

How does Hydrogen Peroxide work?

Mechanism-of-action class: Unknown Cellular or Molecular Interaction.

What is Hydrogen Peroxide used for?

According to FDA labeling, Hydrogen Peroxide carries indications including: Uses first aid to help prevent the risk of infection in minor cuts, scrapes and burns aids in the removal of phlegm, mucous, or other secretions associated with occasional sore mouth. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Hydrogen Peroxide?

Hydrogen Peroxide is classified as Antiinfectives, Antiinfectives and antiseptics for local oral treatment, Other antiseptics and disinfectants, Other dermatologicals, Unknown Cellular or Molecular Interaction, Unknown Physiological Effect.

What are the brand names for Hydrogen Peroxide?

Hydrogen Peroxide is marketed under brand names including ActiveOxy, Astri-UC, Eskata, Oxy Gard, Oxycide, Periogel, Perox-A-Mint, Peroxi-Fresh.