Hypochlorite

• Uses To prevent and treat infections of the skin and tissue.

Directions Pour on or apply to affected area. For wound management, use as an irrigant, cleanser, or the wetting agent for a wet-to-moist dressing. Apply once daily for lightly to moderately exudative wounds. Apply twice daily for highly exudative or highly contaminated wounds. Protect intact skin with a moisture barrier ointment or skin sealant as needed.

For external use only.

1. 1Completed Suicide3012%
2. 2Hypotension228.9%
3. 3Toxicity To Various Agents228.9%
4. 4Off Label Use187.3%
5. 5Oedema156.1%
6. 6Syncope156.1%
7. 7Agitation145.7%
8. 8Death145.7%
9. 9Hyponatraemia145.7%
10. 10Product Use In Unapproved Indication145.7%
11. 11Acute Kidney Injury135.3%
12. 12Alopecia135.3%
13. 13Dermatitis Exfoliative Generalised124.9%
14. 14Drug Ineffective124.9%
15. 15Drug Reaction With Eosinophilia And Systemic Symptoms124.9%

Recent PubMed references pinned to Hypochlorite as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Evaluation of Fracture Resistance of Tooth Fragment Reattached with Cavity Disinfectants in Primary and Permanent Teeth: An In Vitro Study.
  The journal of contemporary dental practice · 2026 · Bhosale KP, Chamarthi VR, Kalaivanan D, et al.
  PMID 42281318DOI 10.5005/jp-journals-10024-4027
• Bactericidal, fungicidal, and antiviral activity of highly purified hypochlorous acid water.
  Journal of microorganism control · 2026 · Mokudai T, Iwasawa A, Kikuchi K, et al.
  PMID 42270376DOI 10.4265/jmc.31.2_67
• HYPOChLorous Acid TEsting Studies in elective groin VASCULAR surgery (HYPOCLATES:VASCULAR): protocol for an ambispective cohort study evaluating a standard change to hypochlorous acid lavage in patients undergoing elective groin vascular surgery.
  BMC surgery · 2026 · Nadvornik MP, Uhl J, Hoch Al Hessen T, et al.
  PMID 42243808DOI 10.1186/s12893-026-03902-3
• Enhancing microbial safety and enzymatic stability of green peas using sequential sodium hypochlorite washing and continuous in-package DBD plasma treatment.
  Food research international (Ottawa, Ont.) · 2026 · Muhammad AI, Atta-Delgado MX, Ji F, et al.
  PMID 42215119DOI 10.1016/j.foodres.2026.119452
• A cellulose-based near-infrared fluorescent probe for rapid hypochlorous acid detection, ferroptosis monitoring, and in vivo imaging.
  Carbohydrate polymers · 2026 · Chen Y, Li S, Liu K, et al.
  PMID 42173566DOI 10.1016/j.carbpol.2026.125438
• A Convenient and Portable Turn-On Fluorescent Probe for Reliable Detection of Hypochlorite: Smartphone-Based Application.
  Luminescence : the journal of biological and chemical luminescence · 2026 · Choi Y, Batsaikhan O, Kim C, et al.
  PMID 42170775DOI 10.1002/bio.70507
• Smear Layer Removal Efficacy of Sodium Hypochlorite Agitated Mixtures with Etidronate or a Glycocholic Acid-Based Solution: A Laboratory Study.
  European endodontic journal · 2026 · Padilla CS, De Pablo OV, Perez-Alfayate R, et al.
  PMID 42126164DOI 10.65717/eej.2026.25140
• Clinical Characteristics and Predictors of Chemical Irrigant-Related Soft Tissue Injuries in Endodontic Practice: A Retrospective Study.
  European endodontic journal · 2026 · Beşkoç C, Gül TG, Çınar İÇ, et al.
  PMID 42126068DOI 10.65717/eej.2026.25113

The 10 most recently updated of 256 ClinicalTrials.gov registrations naming Hypochlorite as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Comparison of Endodontic Postoperative Pain Using Different Irrigation Systems
  Completed · Interventional · 108 enrolled · Qassim University
  NCT06358833updated 2026-06-12
• Biological, Radiographic and Clinical Evaluation of Various Inter-Visit Root Canal Dressings in Retreatment Cases
  Recruiting · Phase 1 · Interventional · 60 enrolled · Ain Shams University
  NCT07641933updated 2026-06-12
• Effects of Treatments on Atopic Dermatitis
  Recruiting · Phase 2 · Interventional · 130 enrolled · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
  NCT01631617updated 2026-06-09
• Bacterial Profiles in Primary Apical Periodontitis Using 16S rRNA PCR
  Completed · Interventional · 24 enrolled · Hasanuddin University
  NCT07637305updated 2026-06-09
• Bacterial Profile Changes During Different Sodium Hypochlorite Irrigation Regimens and Calcium Hydroxide Medicament in Root Canal Treatment
  Completed · Interventional · 24 enrolled · Hasanuddin University
  NCT07623278updated 2026-06-05
• Effect of Two Different Concentrations of Sodium Hypochlorite on Post-Operative Pain Following Single-Visit Root Canal Treatment
  Not yet recruiting · Interventional · 116 enrolled · College of Physicians and Surgeons Pakistan
  NCT07618182updated 2026-06-01
• Comparison of Ultrasonic vs 980-nm Diode Laser Irrigant Activation for Reducing Residual Bacterial DNA in Necrotic Teeth
  Completed · Interventional · 16 enrolled · Hasanuddin University
  NCT07607028updated 2026-05-26
• Evaluation of Post Operative Pain After Using Intracranial Cryotherapy During Single Visit RCT
  Not yet recruiting · Interventional · 60 enrolled · Islamabad Medical and Dental College
  NCT07598188updated 2026-05-20
• Diode Laser-Assisted Direct Pulp Capping Trial
  Completed · Interventional · 56 enrolled · Hue University of Medicine and Pharmacy
  NCT07593508updated 2026-05-18
• Metagenomic Analysis and Postoperative Pain in Infected Root Canals Using Different Irrigation Protocols
  Not yet recruiting · Interventional · 40 enrolled · Suez Canal University
  NCT07546773updated 2026-05-04

Frequently asked questions

What is Hypochlorite used for?

According to FDA labeling, Hypochlorite carries indications including: Uses To prevent and treat infections of the skin and tissue.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What are the brand names for Hypochlorite?

Hypochlorite is marketed under brand names including Anasept, Di-Dak-Sol, Hysept.