Iron

Mechanism-of-action class: Electrolyte Activity.

• Use: For temporary relief of exhaustion, muscle weakness, pallor. May also be used for standard homeopathic indications or as directed by your physician.

Directions for Use: Place drops under tongue for 30 seconds. Adults 7 drops 3 times a day. Children 2-12 years, 7 drops 3 times a day. Under 2 years, consult your doctor. Use until symptoms are relieved or as directed by your health care provider.

Consult your health care provider if symptoms persist more than 5 days or worsen.

• Apr 29, 1974NDANDA017441Allergan
• Nov 6, 2000NDANDA021135Am Regent
• Aug 8, 2025ANDAANDA212340Sandoz
• Aug 8, 2025ANDAANDA208977Intl Medication Sys
• Aug 8, 2025ANDAANDA212559Mylan Labs Ltd

1. 1Fatigue6,3418.2%
2. 2Off Label Use5,8727.6%
3. 3Nausea5,7867.5%
4. 4Diarrhoea5,4857.1%
5. 5Dyspnoea4,7456.2%
6. 6Drug Ineffective4,5916.0%
7. 7Headache4,3545.7%
8. 8Pain4,0755.3%
9. 9Dizziness3,7374.9%
10. 10Arthralgia3,5724.6%
11. 11Vomiting3,4264.5%
12. 12Asthenia3,2124.2%
13. 13Anaemia2,9793.9%
14. 14Malaise2,8623.7%
15. 15Abdominal Pain2,6893.5%

Recent PubMed references pinned to Iron as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Genotype-specific responses of common bean to water deficit: mitigation by foliar-applied Fe, Zn, and Mn.
  Scientific reports · 2026 · Wanas MA, Salama AN, Abdelmotagaly MNM, et al.
  PMID 42260013DOI 10.1038/s41598-026-53639-5
• Urogenital infections select for reduced ability to grow in a low-iron environment and reduced blood survival for Staphylococcus aureus.
  Microbiology (Reading, England) · 2026 · Kearney KP, Ledger EVK, Recker M, et al.
  PMID 42258294DOI 10.1099/mic.0.001691
• Enhanced deep nitrogen removal from low C/N wastewater via manganese-catalyzed iron-carbon micro-electrolysis coupled biological system: performance, mechanism, and microbial adaptability.
  World journal of microbiology & biotechnology · 2026 · Liu H, Wang K, Sha F, et al.
  PMID 42252354DOI 10.1007/s11274-026-05075-w
• Chronic low-dose iron exposure induces GPX4-mediated resistance to ferroptosis in a human chondrocyte cell line.
  Cell and tissue research · 2026 · Karim A, Shafarin J, Suresh S, et al.
  PMID 42249977DOI 10.1007/s00441-026-04082-5
• Rationally engineered icosahedral-spindle aluminum-based metal-organic frameworks with dual-state luminescence for on-site detection of ferric ions in food and human serum.
  Mikrochimica acta · 2026 · Ameen SSM, Algethami FK, Omer KM, et al.
  PMID 42249964DOI 10.1007/s00604-026-08185-2
• The cysteine metabolic regulation through CSE-transsulfuration pathway is essential in iron-induced oxidative damage of heart.
  Redox report : communications in free radical research · 2026 · Zhang Y, Xin Y, Zhou J, et al.
  PMID 42246934DOI 10.1080/13510002.2026.2684348
• Smartphone-Assisted Chemiluminescence System to Detect Fe in Drinking Water Samples.
  Luminescence : the journal of biological and chemical luminescence · 2026 · Bhurgy AS, Assudani PJ
  PMID 42246231DOI 10.1002/bio.70529
• Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review).
  Molecular medicine reports · 2026 · Ge L, Zhang T, Yu J, et al.
  PMID 42246156DOI 10.3892/mmr.2026.13931

The 10 most recently updated of 2,391 ClinicalTrials.gov registrations naming Iron as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Host-Diet-Gut Interaction Post Vegan Diet in Pediatric Autoimmune Hepatitis.
  Recruiting · Interventional · 40 enrolled · Institute of Liver and Biliary Sciences, India
  NCT07118657updated 2026-06-12
• Hot Flashes and Neurovascular Function in Women
  Recruiting · Interventional · 120 enrolled · Mayo Clinic
  NCT05193968updated 2026-06-12
• Decompensation of Cirrhosis and Iron Metabolism
  Completed · Observational · 98 enrolled · Rennes University Hospital
  NCT04807023updated 2026-06-12
• Impact of Transferrin Saturation Guided Maintenance Treatment on Quality of Life in HFE Haemochromatosis
  Active not recruiting · Interventional · 239 enrolled · Rennes University Hospital
  NCT04779593updated 2026-06-12
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CTX001 in Healthy Adults.
  Recruiting · Early phase 1 · Interventional · 72 enrolled · Cajal Therapeutics Inc.
  NCT07577817updated 2026-06-12
• Bone Status on Patients With Genetic Hemochromatosis: a 3 Years Descriptive and Evolutionary Study
  Completed · Observational · 100 enrolled · Rennes University Hospital
  NCT01556360updated 2026-06-12
• Intravenous Iron to Improve Symptoms, Quality of Life and Exercise Capacity in HFpEF With Iron Deficiency
  Not yet recruiting · Phase 2 · Interventional · 150 enrolled · Government of Jersey
  NCT07643818updated 2026-06-12
• Different Efficacy of IFA Supplementation Among Obese and Non-obese Women
  Completed · Interventional · 165 enrolled · Griffith University
  NCT06622551updated 2026-06-11
• Hepcidin: a Prognostic Marker of Morbidity and Mortality in Severe Sepsis?
  Completed · Observational · 114 enrolled · Rennes University Hospital
  NCT03682003updated 2026-06-11
• FACE-APPS-Based Approach for Improving Iron Deficiency Anaemia Indicators Among Female Adolescents at Marginalized Communities
  Recruiting · Interventional · 160 enrolled · Cairo University
  NCT07633262updated 2026-06-10

Frequently asked questions

How does Iron work?

Mechanism-of-action class: Electrolyte Activity.

What is Iron used for?

According to FDA labeling, Iron carries indications including: Use: For temporary relief of exhaustion, muscle weakness, pallor. May also be used for standard homeopathic indications or as directed by your physician.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Iron?

Iron is classified as Electrolyte Activity, Increased Erythroid Cell Production.