pharmacopeia
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/api/v1/drug/levonorgestrel

Mechanism of action

Sourced from openFDA

Mechanism-of-action class: Progestational Hormone Receptor Agonists.

Progestational Hormone Receptor

Indications

Sourced from openFDA
  • Use for women to reduce chance of pregnancy after unprotected sex (if a contraceptive failed or if you did not use birth control)ICD-10: Z30.9

Dosage & administration

Sourced from openFDA

Directions • take as soon as possible within 72 hours (3 days) after unprotected sex. The sooner you take it the better it will work. • if you vomit within 2 hours after taking the medication, call a healthcare professional to find out if you should repeat the dose

Warnings & precautions

Sourced from openFDA

Allergy alert: Do not use if you have ever had an allergic reaction to levonorgestrel Sexually transmitted diseases (STDs) alert: This product does not protect against HIV/AIDS or other STDs Do not use • if you are already pregnant (because it will not work) • for regular birth control Ask a doctor or pharmacist before use if you are taking efavirenz (HIV medication) or rifampin (tuberculosis treatment) or medication for seizures (epilepsy). These medications may reduce the effectiveness of levonorgestrel. When using this product you may have • menstrual changes • tiredness • breast pain • nausea • headache • vomiting • lower stomach (abdominal) pain • dizziness Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)

Approval history

Sourced from openFDA
  • Dec 6, 2000NDANDA021225Bayer Hlthcare
  • Sep 5, 2003NDANDA021544Teva Branded Pharm
  • Nov 21, 2003NDANDA021258Bayer Hlthcare
  • May 25, 2006NDANDA021840Teva Branded Pharm
  • Oct 24, 2008NDANDA022262Teva Branded Pharm
  • Jul 10, 2009NDANDA021998Fdn Consumer
  • Jan 9, 2013NDANDA203159Bayer Hlthcare
  • Mar 28, 2013NDANDA204061Teva Branded Pharm

FAERS reports

View JSON
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
205,479 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
  1. 1Device Expulsion45,20922%
  2. 2Device Dislocation20,1889.8%
  3. 3Menstruation Irregular15,0537.3%
  4. 4Vaginal Haemorrhage15,0307.3%
  5. 5Genital Haemorrhage11,0545.4%
  6. 6Abdominal Pain Lower9,2594.5%
  7. 7Nausea8,8404.3%
  8. 8Abdominal Pain8,6584.2%
  9. 9Procedural Pain8,3674.1%
  10. 10Pain7,6603.7%
  11. 11Uterine Perforation7,4253.6%
  12. 12Drug Ineffective7,4223.6%
  13. 13Pelvic Pain6,8483.3%
  14. 14Headache6,7283.3%
  15. 15Pregnancy With Contraceptive Device5,9152.9%

Literature

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Recent PubMed references pinned to Levonorgestrel as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

Clinical trials

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The 10 most recently updated of 486 ClinicalTrials.gov registrations naming Levonorgestrel as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

Frequently asked questions

How does Levonorgestrel work?
Mechanism-of-action class: Progestational Hormone Receptor Agonists.
What is Levonorgestrel used for?
According to FDA labeling, Levonorgestrel carries indications including: Use for women to reduce chance of pregnancy after unprotected sex (if a contraceptive failed or if you did not use birth control). This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
What class of drug is Levonorgestrel?
Levonorgestrel is classified as Emergency contraceptives, Progestogens, Progestin, Progestin-containing Intrauterine System, Progestational Hormone Receptor Agonists, Decreased Embryonic Implantation, Hypothalamic Endocrine Activity Alteration, Increased Blood Pressure, Inhibit Ovulation, Inhibit Ovum Fertilization.
What are the brand names for Levonorgestrel?
Levonorgestrel is marketed under brand names including After banger, AfterPlan, Aftera, Afterpill, Climara Pro, Curae, E-Con, EContra.
Note. Data for levonorgestrel is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.

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