Limonene

• after cleansing, use the embossing side of the pad to gently wipe across face except the eye area use the gauze side of the pad to wipe dead skin prone areas again like the nose, chin, and around the lips pat the fact to absorb moisture from the remaining essence

for external use only

This product is for exeternal use only. Do not use for internal use Storage and handling precautions If possible, avoid direct sunlight and store in cool and area of low humidity in order to maintain the quality of the product and avoid misuse Avoid placing the product near fire and store out in reach of children - consult a physician in case of abnormal symptoms, such as red spots, swelling or itching, or side effects in the areas of application due to direct light during or after using the product - do not use on wounded area

1. 1Eosinophilia655%
2. 2Rash Maculo-papular655%
3. 3Tongue Oedema655%
4. 4Affective Disorder19.1%
5. 5Blood Pressure Decreased19.1%
6. 6Blood Pressure Increased19.1%
7. 7Cardio-respiratory Arrest19.1%
8. 8Death19.1%
9. 9Depression19.1%
10. 10Dermal Absorption Impaired19.1%
11. 11Drug Ineffective19.1%
12. 12Gastrointestinal Disorder19.1%
13. 13Infective Exacerbation Of Bronchiectasis19.1%
14. 14Mood Altered19.1%
15. 15Off Label Use19.1%

Recent PubMed references pinned to Limonene as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• (R)-(+)-limonene: a promising antifungal agent against Candida glabrata.
  Brazilian journal of biology = Revista brasleira de biologia · 2026 · Pires BA, Medeiros CIS, Santos JRDA, et al.
  PMID 42138952DOI 10.1590/1519-6984.304908
• Coupled mesoporous silica nanoparticles and limonene-chitosan Pickering emulsions: enhanced insecticidal delivery and selectivity.
  Journal of nanobiotechnology · 2026 · Lv N, Xu Z, Zhang Q, et al.
  PMID 41857614DOI 10.1186/s12951-026-04172-0
• Biosynthesis of Limonene Using Acetate as the Carbon Source in Metabolically Engineered Escherichia coli.
  Journal of agricultural and food chemistry · 2026 · Zhao W, Shang Y, Pan M, et al.
  PMID 41811345DOI 10.1021/acs.jafc.5c14638
• Novel eugenol/limonene nanoplatform as a new remedy against bacterial lung infections.
  Scientific reports · 2026 · Elwakil BH, Shaaban MM, Bakr BA, et al.
  PMID 41741515DOI 10.1038/s41598-026-38114-5
• Ten Years of Patch Testing to Hydroperoxides of Limonene and Linalool: Prevalence, Patterns and Clinical Insights.
  Contact dermatitis · 2026 · Botvid S, Søgaard R, Schwensen JFB, et al.
  PMID 41638887DOI 10.1111/cod.70102
• Involvement of Multiple Ion Channels and Receptors in Mediating the Insecticidal and Repellent Actions of Limonene.
  International journal of molecular sciences · 2025 · Li Y, Valbon W, Andreazza F, et al.
  PMID 41516290DOI 10.3390/ijms27010416
• Dose-Sparing Efficacy of d-Limonene with Low-Dose Allopurinol in a Dual Model of Hyperuricemia and Gouty Arthritis in Rats.
  Nutrients · 2025 · Venkatesan K, Muralidharan P, Sivadasan D, et al.
  PMID 41515190DOI 10.3390/nu18010072
• D-limonene modulates AMPK signaling to inhibit ox-LDL-induced foam cell formation.
  Scientific reports · 2025 · Luo G, Fang F, Guo Y, et al.
  PMID 41469726DOI 10.1038/s41598-025-29351-1

The 10 most recently updated of 34 ClinicalTrials.gov registrations naming Limonene as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies
  Recruiting · Phase 4 · Interventional · 16 enrolled · Rigel Pharmaceuticals
  NCT07486713updated 2026-06-05
• Behavioral Pharmacology of Orally Administered THC and D-limonene
  Recruiting · Phase 1 · Interventional · 65 enrolled · Johns Hopkins University
  NCT06378957updated 2026-05-28
• The Effects of Lemon Essential Oil Inhalation on Attention in Children With Attention Deficit Hyperactivity Disorder (ADHD)
  Completed · Interventional · 52 enrolled · Başakşehir Çam & Sakura City Hospital
  NCT07586761updated 2026-05-14
• Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency
  Active not recruiting · Phase 3 · Interventional · 10 enrolled · Grace Science, LLC
  NCT06199531updated 2026-05-04
• The Impact of Simulated Forest Immersion Therapy on Pain and Anxiety in Patients Axial Spondyloarthritis (axSpA)
  Completed · Interventional · 10 enrolled · Oregon Health and Science University
  NCT06072859updated 2025-07-31
• d-Limonene +Radiation +PlatinumBasedChemo for Xerostomia Prevention in LocallyAdvanced HNSCC
  Recruiting · Phase 1 · Interventional · 40 enrolled · Stanford University
  NCT04392622updated 2025-07-20
• The Effect of Sweet Orange Aromatherapy on Anxiety and Pulse Level of Nurse Students
  Completed · Interventional · 95 enrolled · Inonu University
  NCT06843837updated 2025-03-03
• CYP2C19 Variants and Limonene Metabolism
  Recruiting · Interventional · 20 enrolled · Stanford University
  NCT05078723updated 2024-12-16
• New Non-invasive Biomarkers of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)
  Completed · Observational · 172 enrolled · General University Hospital, Prague
  NCT06647095updated 2024-11-01
• Treatment of Adults With Acute Bronchitis in the Primary Healthcare Setting
  Completed · Interventional · 310 enrolled · Neopharm Bulgaria Ltd.
  NCT06142994updated 2024-10-30

Frequently asked questions

What is Limonene used for?

According to FDA labeling, Limonene carries indications including: after cleansing, use the embossing side of the pad to gently wipe across face except the eye area use the gauze side of the pad to wipe dead skin prone areas again like the nose, chin, and around the lips pat the fact to absorb moisture from the remaining essence. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.