Lipase
/api/v1/drug/lipaseIndications
Sourced from openFDA- Take 15 minutes before meals.
Dosage & administration
Sourced from openFDADIRECTIONS Adults and children 12 years and older 20 drops in a little water, 2 times per day Children between 12 years and 6 years of age 10 drops in a little water, 2 times per day Children under 6 years 5 drops in a glass of water, 2 times per day
Warnings & precautions
Sourced from openFDAStop use and ask doctor if symptoms persist more than 5 days or worsen. I f pregnant or breast-feeding ask a health professional before use. Keep out of reach of children . In case of overdose, get medical help or contact a Poison Control Center right away. Contains ethyl alcohol 30%
Approval history
Sourced from openFDA- Aug 27, 2009BLABLA022210Eurand Pharma Ltd
- Apr 12, 2010BLABLA022523Vivus Inc
FAERS reports
- 1Diarrhoea5578.1%
- 2Infective Pulmonary Exacerbation Of Cystic Fibrosis4746.9%
- 3Hospitalisation3314.8%
- 4Death3244.7%
- 5Nausea3214.7%
- 6Cystic Fibrosis3064.4%
- 7Headache2944.3%
- 8Fatigue2804.1%
- 9Pneumonia2703.9%
- 10Weight Decreased2403.5%
- 11Drug Ineffective2283.3%
- 12Dyspnoea2253.3%
- 13Abdominal Pain Upper2243.2%
- 14Constipation2223.2%
- 15Abdominal Pain2163.1%
Literature
Recent PubMed references pinned to Lipase as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Endothelial Lipase RS3744843 Polymorphism and Lipid Profile in Bechet's Disease Patients.La Tunisie medicale · 2026 · Makhlouf R, Messedi M, Snoussi M, et al.PMID 42246713DOI 10.62438/tunismed.v104i03.6217
- Tumor Markers and Pancreatic Enzymes Reflect Early Pancreatic Dysfunction in Type 2 Diabetes.Saudi medical journal · 2026 · Mohammedsaeed W, Alharbi S, Alraddadi L, et al.PMID 42238214DOI 10.15537/1658-3175.8792
- Low-Cost Agro-Industrial Waste-Based Production of Lipase by Aspergillus flavus and Its Application in Brassica napus Seed Germination.Journal of oleo science · 2026 · Bashir T, Ullah N, Sarwar A, et al.PMID 42219365DOI 10.5650/jos.ess26016
- Photoenzymatic Catalytic Process with Reaction-Separation Coupling for the Synthesis of Biobased Plasticizers.Journal of agricultural and food chemistry · 2026 · Zhang H, Yu S, Cui Z, et al.PMID 42207191DOI 10.1021/acs.jafc.6c03145
- The Effective Biodegradation of Poly(ε-caprolactone) by Engineered Yeast Yarrowia lipolytica Producing Lipase B.International journal of molecular sciences · 2026 · Zdanowska Ż, Serrano-Aguirre L, Urbanek AK, et al.PMID 42196601DOI 10.3390/ijms27104625
- Synthesis and preliminary enzymatic evaluation of polyol-based 4-phenylbutyrate derivatives.Bioorganic & medicinal chemistry letters · 2026 · Suchetti L, Tempesti TC, Ferrayoli C, et al.PMID 42167552DOI 10.1016/j.bmcl.2026.130689
- Synthesis, Molecular Modelling, In Vitro and Pharmacological Evaluation of Coumarin Analogues as Potential Anti-Obesity Agents.Archiv der Pharmazie · 2026 · Yadav N, Lavanya BB, Paul AT, et al.PMID 42152231DOI 10.1002/ardp.70259
- Differential digestive fate of palm oil and palm-based diacylglycerol oil: linking physicochemical properties, oxidative stability and pancreatic lipase specificity.Food chemistry · 2026 · Hu T, Chen J, Tan CP, et al.PMID 42143920DOI 10.1016/j.foodchem.2026.149547
Clinical trials
The 10 most recently updated of 204 ClinicalTrials.gov registrations naming Lipase as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic InsufficiencyRecruiting · Phase 4 · Interventional · 30 enrolled · Ohio State UniversityNCT06477159updated 2026-06-10
- Phase 2 Study to Assess the Safety and Efficacy of ANG003Recruiting · Phase 2 · Interventional · 113 enrolled · Anagram Therapeutics, Inc.NCT07450547updated 2026-06-10
- SMART Diets for MASLDRecruiting · Phase 2 · Interventional · 102 enrolled · Michigan State UniversityNCT07459504updated 2026-06-01
- Long Term Efficacy and Safety of Orlistat for Type 1 HyperlipoproteinemiaRecruiting · Phase 2 · Interventional · 28 enrolled · University of Texas Southwestern Medical CenterNCT05816343updated 2026-05-29
- A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489 as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis (MS)Recruiting · Phase 2 · Interventional · 360 enrolled · Hoffmann-La RocheNCT07282574updated 2026-05-22
- Prophylaxis Against Post-Endoscopic Retrograde Cholangio-Pancreatography Pancreatitis.Completed · Phase 3 · Interventional · 60 enrolled · Hospital General de Chihuahua - Dr. Salvador Zubirán AnchondoNCT07599605updated 2026-05-20
- Lysosomal Acid Lipase Deficiency in Risk GroupsRecruiting · Observational · 1,200 enrolled · AstraZenecaNCT07455864updated 2026-05-15
- Evaluating the Efficacy of RELiZORB in Managing Exocrine Pancreatic Insufficiency in Tube-fed Pancreatitis PatientsRecruiting · Phase 3 · Interventional · 60 enrolled · Massachusetts General HospitalNCT06691893updated 2026-05-15
- Evaluating RELiZORB Use for the Treatment of Feeding Intolerance in Adults With Moderate to Severe Acute PancreatitisEnrolling by invitation · Phase 4 · Interventional · 15 enrolled · Northwell HealthNCT07583342updated 2026-05-13
- Pancreatic Enzyme Replacement in Acute Necrotizing PancreatitisRecruiting · Phase 3 · Interventional · 140 enrolled · Asian Institute of Gastroenterology, IndiaNCT07441824updated 2026-05-05
Frequently asked questions
- What is Lipase used for?
- According to FDA labeling, Lipase carries indications including: Take 15 minutes before meals.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What are the brand names for Lipase?
- Lipase is marketed under brand names including Creon, PanaKare, PancrePlus, Pancreaze, Pertzye, Viokace, Zenpep.
lipase is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.