Magnesium Carbonate

Mechanism-of-action classes: Acid-Base Activity; Electrolyte Activity; Enzyme Interactions.

• Use For the temporary relief of upset stomach or sour stomach, and acid indigestion.

Directions (Shake well before using) Follow dosage below or as directed by a doctor. Adults and children 12 yrs. and older: 2 tsps. every 3 to 4 hrs. Children under 12 yrs. of age: consult a doctor before use. Children under 12 yrs. of age: Consult a doctor befor use. (6/2021)

Do not use if you have kidney desease.

• Oct 2, 1990NDANDA019481United Guardian

1. 1Nausea6247.8%
2. 2Vomiting5657.1%
3. 3Off Label Use5637.1%
4. 4Headache5426.8%
5. 5Pain5286.6%
6. 6Diarrhoea5256.6%
7. 7Fatigue4976.2%
8. 8Drug Ineffective4956.2%
9. 9Dyspnoea4705.9%
10. 10Chronic Kidney Disease4675.8%
11. 11Malaise4565.7%
12. 12Pyrexia4475.6%
13. 13Acute Kidney Injury4115.1%
14. 14Abdominal Pain3664.6%
15. 15Abdominal Pain Upper3554.4%

Recent PubMed references pinned to Magnesium Carbonate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Symbiotic bacteria may support calcium carbonate precipitation in the Gulf toadfish.
  PLoS biology · 2026 · Bonacolta AM, Kravitz T, Mozo R, et al.
  PMID 42149909DOI 10.1371/journal.pbio.3003764
• Hierarchical laminin-MgCO(3) gradient layers on Sr/ZnO ion-implanted titanium for multifunctional bone regeneration.
  Artificial cells, nanomedicine, and biotechnology · 2026 · Lenka R, Swain S, Misra RDK, et al.
  PMID 42037100DOI 10.1080/21691401.2026.2649072
• Trimineralic abalone shells (Haliotis iris Gmelin, 1791) and X-ray diffractometry: A Bayesian calibration model for resolving complex skeletal mineralogy.
  PloS one · 2026 · Smith AM, Dillingham PW, Hassan C, et al.
  PMID 42013181DOI 10.1371/journal.pone.0346638
• Oral calcium carbonate as an adjunct to oxytocin infusion for labor induction: a randomized controlled pilot study on feasibility and acceptability.
  American journal of obstetrics & gynecology MFM · 2026 · Boers JRM, Garcia M, Sanchez E, et al.
  PMID 41956322DOI 10.1016/j.ajogmf.2026.101963
• Synergistic phosphorus-carboxyl co-modification of dolomite for enhanced immobilization and long-term stabilization of Pb in acidic contaminated soils.
  Environmental research · 2026 · Sun J, Zhu F, Zhang R, et al.
  PMID 41881237DOI 10.1016/j.envres.2026.124353
• Proton channels govern vesicular carbonate chemistry in mineralizing cells of a marine calcifier.
  Nature communications · 2026 · Jonusaite S, Przibylla-Diop C, Musinszki M, et al.
  PMID 41844652DOI 10.1038/s41467-026-70837-x
• Modulation of gut microbiota in rainbow trout by dietary protein-to-energy ratio and calcium carbonate through chyme and nutrient digestibility changes.
  Animal : an international journal of animal bioscience · 2026 · Ruiz A, Ciavoni E, Nederlof MAJ, et al.
  PMID 41643414DOI 10.1016/j.animal.2026.101754
• Trade-offs between root water uptake and xylem-leaf water-use traits underpin contrasting plant adaptation strategies in limestone and dolomite habitats.
  Tree physiology · 2026 · Liu W, Nie Y, Behzad HM, et al.
  PMID 41626742DOI 10.1093/treephys/tpag013

The 10 most recently updated of 55 ClinicalTrials.gov registrations naming Magnesium Carbonate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy
  Recruiting · Phase 1 · Phase 2 · Interventional · 30 enrolled · Ferring Pharmaceuticals
  NCT04113382updated 2026-04-09
• PhytoSERM to Prevent Menopause Associated Decline in Brain Metabolism and Cognition
  Active not recruiting · Phase 2 · Interventional · 100 enrolled · Roberta Brinton
  NCT05664477updated 2026-03-13
• Quality of Life in Diarrhea-predominant Irritable Bowel Syndrome Taking GABA
  Completed · Interventional · 20 enrolled · University of Pisa
  NCT06755489updated 2026-02-05
• Clinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improving Skin Health and Reducing Signs of Aging on Healthy Adult Male and Female Subjects.
  Not yet recruiting · Interventional · 50 enrolled · NovoBliss Research Pvt Ltd
  NCT07324759updated 2026-01-07
• Efficacy Study of a Food Supplement With Myo-inositol, N-Acetyl-Cystein, Zinc and Vitamins on Sperm DNA Fragmentation
  Recruiting · Interventional · 72 enrolled · GYNOV
  NCT04959864updated 2025-08-22
• Efect Supplementation Vitamin D in Diabetes Mellitus Type 2
  Completed · Interventional · 92 enrolled · Trisakti University
  NCT07019415updated 2025-06-13
• Open-Label Placebo Treatment of Women With Premenstrual Syndrome
  Completed · Interventional · 150 enrolled · Jens Gaab
  NCT03547661updated 2025-06-05
• Conditioned Open-label Placebos to Facilitate Opioid Reduction in Patients With Chronic Non-cancer Pain
  Recruiting · Interventional · 86 enrolled · Cosima Locher
  NCT06350786updated 2025-04-22
• Study Comparing Esomeprazole Associated With Sodium Bicarbonate From Eurofarma and Esomeprazole in Treatment of Gastroesophageal Reflux Disease ESOBIC
  Withdrawn · Phase 3 · Interventional · 0 enrolled · Eurofarma Laboratorios S.A.
  NCT01471925updated 2025-04-01
• A Study to Assess the Pharmacokinetics of Sorafenib in Mesoporous Magnesium Carbonate (DPH001) Compared to Nexavar® (sorafenib) in Healthy Volunteers
  Completed · Early phase 1 · Interventional · 12 enrolled · Disruptive Pharma
  NCT06797427updated 2025-03-17

Frequently asked questions

How does Magnesium Carbonate work?

Mechanism-of-action classes: Acid-Base Activity; Electrolyte Activity; Enzyme Interactions.

What is Magnesium Carbonate used for?

According to FDA labeling, Magnesium Carbonate carries indications including: Use For the temporary relief of upset stomach or sour stomach, and acid indigestion.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Magnesium Carbonate?

Magnesium Carbonate is classified as Magnesium compounds, Osmotically acting laxatives, Acid-Base Activity, Electrolyte Activity, Enzyme Interactions, Cellular Activity Alteration, Gastric Acid Alteration.

What are the brand names for Magnesium Carbonate?

Magnesium Carbonate is marketed under brand names including Acid Gone, Gaviscon, MagneBind, MagneBind 400 Rx, Magonate Reformulated May 2022, Medi-Lyte, Renacidin.