Magnesium Oxide
GET
/api/v1/drug/magnesium-oxideMechanism of action
Sourced from openFDAMechanism-of-action classes: Acid-Base Activity; Electrolyte Activity; Enzyme Interactions; Osmotic Activity.
Indications
Sourced from openFDA- Use relieves: ■ acid indigestion ■ upset stomach
Dosage & administration
Sourced from openFDADirections take one or two antacid tablets daily. Do not exceed two tablets unless directed by a physician.
Warnings & precautions
Sourced from openFDAAsk a doctor before use if you have kidney disease you are taking a prescription drug (antacids may interact with certain prescription drugs) you are pregnant or breast feeding. Do not take more than 2 tablets in a 24 hour period. May have a laxative effect. Keep out of reach of children.
Approval history
Sourced from openFDA- Nov 28, 2017NDANDA209589Ferring Pharms Inc
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
41,678 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Nausea2,9687.1%
- 2Diarrhoea2,7146.5%
- 3Fatigue2,5356.1%
- 4Dyspnoea2,1345.1%
- 5Pneumonia2,0765.0%
- 6Off Label Use2,0514.9%
- 7Pyrexia1,8764.5%
- 8Vomiting1,7994.3%
- 9Headache1,7164.1%
- 10Drug Ineffective1,6644.0%
- 11Death1,6474.0%
- 12Pain1,5313.7%
- 13Anaemia1,5033.6%
- 14Decreased Appetite1,4853.6%
- 15Constipation1,4463.5%
Literature
Recent PubMed references pinned to Magnesium Oxide as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Synergistic antimicrobial and antibiofilm effects of mycosynthesized MnO-MgO bimetallic nanoparticles against drug-resistant pathogens.BMC microbiology · 2026 · Elkady FM, Alsalamah SA, Hashem A, et al.PMID 42157094DOI 10.1186/s12866-026-05152-y
- How additives steer sewage sludge hydrochar properties: Divergent pathways of MgO/CaO versus sawdust in carbon/nutrient fate and magnetism.Bioresource technology · 2026 · Zhang C, Chen G, Wang Q, et al.PMID 42150640DOI 10.1016/j.biortech.2026.134910
- Highly regenerable cubic and terraced MgO nanoparticles as CO(2) adsorbents for room-temperature wet mineral carbonation.Journal of environmental management · 2026 · Cho K, Kang Y, Kim MC, et al.PMID 42150493DOI 10.1016/j.jenvman.2026.129968
- Injectable oxidized sodium alginate/gelatin (OSA/Gel) hydrogel loaded with MgO/SZS for ion-mediated osteogenesis and macrophage polarization.International journal of biological macromolecules · 2026 · Li H, Wang X, Tang J, et al.PMID 42103120DOI 10.1016/j.ijbiomac.2026.152155
- Comparative evaluation of the photocatalytic and antibacterial activities of nanostructured MgO biosynthesized using Chromolaena odorata and Hevea brasiliensis extracts.The Science of the total environment · 2026 · Otabor GO, Uwidia Ikhuoria E, Hilary Ifijen I, et al.PMID 41985431DOI 10.1016/j.scitotenv.2026.181787
- Catalytic performance of La@Mg(12)O(12) as a single atom catalyst toward nitrogen reduction reaction for ammonia generation.Journal of molecular graphics & modelling · 2026 · Kosar N, Mahmood T, Al-Saadi AA, et al.PMID 41962392DOI 10.1016/j.jmgm.2026.109399
- Magnesium Oxide Use and Clinical Outcomes in CKD Patients: Evidence from a Nationwide Population-Based Cohort Study in Taiwan.International journal of medical sciences · 2026 · Hsiao PJ, Tsou LL, Yang CC, et al.PMID 41938509DOI 10.7150/ijms.125059
- Modifying alkali-activated materials with reactive MgO: A comprehensive overview of mechanisms and performance.Environmental science and pollution research international · 2026 · Rashad AMPMID 41886148DOI 10.1007/s11356-026-37506-4
Clinical trials
The 10 most recently updated of 183 ClinicalTrials.gov registrations naming Magnesium Oxide as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Effect of Metformin, a Drug Used to Treat Diabetes, vs PlaceboActive not recruiting · Phase 4 · Interventional · 150 enrolled · University of California, Los AngelesNCT05949008updated 2026-06-08
- Fezolinetant and Vascular Health and Brain HealthNot yet recruiting · Phase 3 · Interventional · 220 enrolled · Rebecca ThurstonNCT07606664updated 2026-05-26
- Comparison of 1 Liter PEG With Ascorbate and Sodium Picosulfate / Magnesium Citrate for High Quality Colon CleansingCompleted · Phase 4 · Interventional · 1,180 enrolled · Parc de Salut MarNCT04598880updated 2026-05-14
- Study on the Effectiveness and Safety of Two Olive Extract- Based (Olea Europea L. Folium) Supplements, Alone or Combined With a Mullein Extract (Verbascum Thapsus L. Herba Cum Floribus), for the Maintenance of Cognitive Function.Not yet recruiting · Interventional · 99 enrolled · ISTITUTO FARMOCHIMICO FITOTERAPICO: EPO SRLNCT07586410updated 2026-05-14
- Preventive Nutritional Supplements for Preclinical PathologiesCompleted · Interventional · 21 enrolled · Centro de Edafología y Biología Aplicada del SeguraNCT07265115updated 2026-04-28
- Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill PatientsRecruiting · Phase 4 · Interventional · 3,253 enrolled · Scarborough General HospitalNCT07173855updated 2026-04-27
- Study Assessing CLENPIQ as Bowel Preparation for Pediatric ColonoscopyRecruiting · Phase 1 · Phase 2 · Interventional · 30 enrolled · Ferring PharmaceuticalsNCT04113382updated 2026-04-09
- Beverage Hydration Index of Different SolutionsRecruiting · Interventional · 30 enrolled · University of MemphisNCT07507344updated 2026-04-07
- RELISTOR's Effects on Opioid-Induced ConstipationWithdrawn · Observational · 0 enrolled · Methodist Health SystemNCT04930237updated 2026-03-23
- Synbiotic Supplement With Botanical Extracts for Gut Microbiota Balance in Irritable Bowel SyndromeNot yet recruiting · Interventional · 8 enrolled · Iuliu Hatieganu University of Medicine and PharmacyNCT07475299updated 2026-03-16
Frequently asked questions
- How does Magnesium Oxide work?
- Mechanism-of-action classes: Acid-Base Activity; Electrolyte Activity; Enzyme Interactions; Osmotic Activity.
- What is Magnesium Oxide used for?
- According to FDA labeling, Magnesium Oxide carries indications including: Use relieves: ■ acid indigestion ■ upset stomach. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Magnesium Oxide?
- Magnesium Oxide is classified as Magnesium, Magnesium compounds, Osmotically acting laxatives, Acid-Base Activity, Electrolyte Activity, Enzyme Interactions, Osmotic Activity, Antacid, Cellular Activity Alteration.
- What are the brand names for Magnesium Oxide?
- Magnesium Oxide is marketed under brand names including Beelith, Clenpiq, Folgard OS, Lactocal, Mag-Ox 400, Magmilax, Phillips' Cramp-free, Somnicin.
Note. Data for
magnesium-oxide is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.