Magnesium Salicylate

Mechanism-of-action class: Cyclooxygenase Inhibitors.

• & USAGE Uses For the temporary relief of minor backache pain

DOSAGE & ADMINISTRATION Directions drink a full glass of water with each dose Adults and children: (12 years and over) Take 2 caplets every 6 hours, not to exceed 8 caplets in 24 hours. Children under 12 years: Do not use unless directed by a doctor

Warnings Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Magnesium salicylate may cause a severe allergic reaction, which may include: hives facial swelling asthma (wheezing) shock Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you: are age 60 or older have had stomach ulcers or bleeding problems take a blood thinning (anticoagulant) or steroid drug take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others) have 3 or more alcohol drinks every day while using this product take more or for a longer time than directed DO NOT USE Do not use if you are allergic to salicylates (including aspirin) or any other pain reliever/fever reducer. ASK DOCTOR Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems such as heartburn you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you have asthma you are taking a diuretic ASK DOCTOR/PHARMACIST Ask a doctor or pharmacist before use if you are taking a prescription drug for gout diabetes arthritis STOP USE Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away.

1. 1Drug Ineffective42848%
2. 2Product Quality Issue38143%
3. 3Fatigue364.0%
4. 4Nausea364.0%
5. 5Dizziness273.0%
6. 6Headache273.0%
7. 7Vomiting262.9%
8. 8Asthenia242.7%
9. 9Off Label Use232.6%
10. 10Anaemia222.5%
11. 11Dyspnoea222.5%
12. 12Pain222.5%
13. 13Diarrhoea212.4%
14. 14Arthralgia171.9%
15. 15Malaise171.9%

Recent PubMed references pinned to Magnesium Salicylate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Low adherence to aspirin and calcium carbonate for preeclampsia prevention in pregnant women with chronic hypertension in a brazilian hospital.
  Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025 · Jardine BV, Barbosa PO, Lima-Júnior LS, et al.
  PMID 41341951DOI 10.61622/rbgo/2025rbgo77
• Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics.
  International journal of toxicology · 2025 · Johnson W Jr, Zhu J, Bergfeld WF, et al.
  PMID 41243163DOI 10.1177/10915818251389456
• Dietary salicylates affect calcium and magnesium status in preeclampsia model rats induced by NG-nitro-L-arginine-methyl ester (L-NAME).
  Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2025 · Cholik RS, Skrypnik K, Karaźniewicz-Łada M, et al.
  PMID 40780040DOI 10.1016/j.jtemb.2025.127711
• Type-dependent biostimulant-mediated induction of nutrients and phenolic compounds improved plant tolerance against canola aphids (Brevicoryne brassicae L.).
  Plant physiology and biochemistry : PPB · 2025 · Javed MW, Mansoor-Ul-Hasan, Sagheer M, et al.
  PMID 40327901DOI 10.1016/j.plaphy.2025.109930
• Pharmacokinetic and Bioequivalence Evaluation of Dihydroxyaluminum Aminoacetate, Heavy Magnesium Carbonate, and Aspirin Tablets in Healthy Chinese Subjects in the Fasting and Postprandial Conditions.
  Clinical pharmacology in drug development · 2024 · Yao F, He Y, Lu P, et al.
  PMID 39081255DOI 10.1002/cpdd.1455
• Increased cytoplasmic Mg2+ level contributes to rice salicylic acid accumulation and broad-spectrum resistance.
  Plant physiology · 2024 · Zeng W, Zhang Y, Tian X, et al.
  PMID 38635966DOI 10.1093/plphys/kiae220
• A Novel Para-Amino Salicylic Acid Magnesium Layered Hydroxide Nanocomposite Anti-Tuberculosis Drug Delivery System with Enhanced in vitro Therapeutic and Anti-Inflammatory Properties.
  International journal of nanomedicine · 2021 · Saifullah B, Arulselvan P, El Zowalaty ME, et al.
  PMID 34703226DOI 10.2147/IJN.S297040
• A Microstirring Pill Enhances Bioavailability of Orally Administered Drugs.
  Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021 · Mundaca-Uribe R, Karshalev E, Esteban-Fernández de Ávila B, et al.
  PMID 34194949DOI 10.1002/advs.202100389

The 10 most recently updated of 16 ClinicalTrials.gov registrations naming Magnesium Salicylate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• IRELAnD: Investigating the Role of Early Low-dose Aspirin in Diabetes
  Completed · Phase 3 · Interventional · 137 enrolled · Royal College of Surgeons, Ireland
  NCT03574909updated 2026-03-27
• Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy（ESAWAAPT）
  Completed · Phase 4 · Interventional · 120 enrolled · Northern Jiangsu People's Hospital
  NCT04645550updated 2025-03-21
• Maximizing Outcomes Needed After Percutaneous Coronary Intervention (PCI) Using Weight Management (MOMENTUM)
  Completed · Interventional · 50 enrolled · University of Nebraska
  NCT01163968updated 2023-09-29
• Topical Piroxicam vs Soulagel in the Treatment of Acute Extremity Pain After Emergency Department Discharge
  Completed · Phase 2 · Phase 3 · Interventional · 1,525 enrolled · University of Monastir
  NCT05054023updated 2022-06-21
• Modulating Glucose Tolerance With Dietary Tyrosine
  Completed · Interventional · 10 enrolled · Columbia University
  NCT03872557updated 2021-05-05
• The Impact of Air Travel on Passenger Cognitive Functions
  Unknown · Phase 2 · Phase 3 · Interventional · 50 enrolled · Dinara Zhumanbayeva
  NCT04802785updated 2021-03-17
• Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection
  Completed · Phase 4 · Interventional · 124 enrolled · Yangzhou University
  NCT02247414updated 2019-03-29
• Project RAD: A Brief Intervention for Young Adult Alcohol or Marijuana Users
  Unknown · Interventional · 44 enrolled · University of Houston
  NCT03801096updated 2019-01-11
• Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy
  Unknown · Phase 4 · Interventional · 60 enrolled · Yangzhou University
  NCT02238444updated 2019-01-02
• Aspirin for Venous Ulcers: Randomised Trial (AVURT)
  Terminated · Phase 2 · Interventional · 26 enrolled · St George's, University of London
  NCT02333123updated 2017-06-27

Frequently asked questions

How does Magnesium Salicylate work?

Mechanism-of-action class: Cyclooxygenase Inhibitors.

What is Magnesium Salicylate used for?

According to FDA labeling, Magnesium Salicylate carries indications including: & USAGE Uses For the temporary relief of minor backache pain. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Magnesium Salicylate?

Magnesium Salicylate is classified as Cyclooxygenase Inhibitors, Decreased Platelet Aggregation, Decreased Prostaglandin Production.

What are the brand names for Magnesium Salicylate?

Magnesium Salicylate is marketed under brand names including Backprin, Doans, Doans PM, MST 600, Nuprin Backache, Pamprin Cramp Formula, Percogesic Backache.