Magnesium Sulfate

Mechanism-of-action classes: Acid-Base Activity; Electrolyte Activity; Enzyme Interactions.

• Uses for relief of occasional constipation (irregularity) this product generally produces bowel movement in 1/2 to 6 hoursICD-10: K59.00

Directions do not exceed recommended daily dosage drink a full glass (8 ounces) of liquid with each dose may be taken as a single daily dose or in divided doses dissolve the dose in 8 ounces of water. Lemon juice may be added to improve the taste. adults and children 12 years and over - 2 to 6 level teaspoons (10 to 30 grams) daily children 6 to under 12 years - 1 to 2 level teaspoons (5 to 10 grams) daily children under 6 years - consult a doctor

for this product

ADVERSE REACTION DISTRIBUTED BY BETTER LIVING BRANDS LLC P.O. BOX 99 PLEASANTON, CA 94566-00096 ‡1-888-723-3929 LOVE IT OR IT'S ON US

• Feb 19, 1982NDANDA018508Baxter Hlthcare
• Sep 8, 1986NDANDA019316Fresenius Kabi Usa
• Jun 24, 1994NDANDA020309Hospira
• Jul 11, 1995NDANDA020488Hospira
• Sep 27, 1996NDANDA020577Lukare Medical Llc
• Aug 5, 2010NDANDA022372Azurity
• Nov 10, 2020NDANDA213135Azurity
• Jun 15, 2023NDANDA215344Azurity

1. 1Vomiting3,01516%
2. 2Nausea2,45813%
3. 3Drug Ineffective1,7479.0%
4. 4Headache9494.9%
5. 5Abdominal Pain9094.7%
6. 6Off Label Use8844.6%
7. 7Pain8564.4%
8. 8Diarrhoea8514.4%
9. 9Pyrexia8254.2%
10. 10Maternal Exposure During Pregnancy7563.9%
11. 11Dyspnoea6913.6%
12. 12Foetal Exposure During Pregnancy6803.5%
13. 13Premature Baby6613.4%
14. 14Fatigue6393.3%
15. 15Malaise6363.3%

Recent PubMed references pinned to Magnesium Sulfate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Antenatal Magnesium Sulfate for Tocolysis and Early Enteral Feeding in Preterm Infants: A Retrospective Cohort Study.
  Pediatrics international : official journal of the Japan Pediatric Society · 2026 · Okuno T, Kabata D, Shimizu T, et al.
  PMID 42186720DOI 10.1111/ped.70446
• Sequence-Dependent Analgesic Efficacy of Ketamine and Magnesium Sulfate After Radical Nephrectomy.
  Medicina (Kaunas, Lithuania) · 2026 · Ladjevic NN, Dzamic Z, Jovanovic VD, et al.
  PMID 42075626DOI 10.3390/medicina62040754
• Protective effect of magnesium on indomethacin-induced gastric ulcer in mice.
  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026 · Rostami R, Eidi A, Mortazavi P, et al.
  PMID 42010200DOI 10.1007/s10534-026-00803-z
• 1 g/h magnesium sulfate maintenance for eclampsia prevention is enough.
  Acta obstetricia et gynecologica Scandinavica · 2026 · Petrecca A, Bina B, Ghi T, et al.
  PMID 41949178DOI 10.1111/aogs.70205
• ANESTHESIA OF MYSTERY SNAILS (POMACEA BRIDGESII) BY USING ETHANOL, EUGENOL, AND MAGNESIUM SULFATE.
  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians · 2026 · Davidson A, Scagnelli A, Mans C, et al.
  PMID 41926251DOI 10.1638/2025-0006
• Factors associated with appropriate administration of magnesium sulfate for neuroprotection prior to early preterm birth.
  American journal of obstetrics & gynecology MFM · 2026 · Hendin N, Gulersen M, Blitz MJ, et al.
  PMID 41881424DOI 10.1016/j.ajogmf.2026.101943
• Antenatal magnesium sulphate for preterm foetal neuroprotection in low- and middle-income countries: a scoping review of research studies and guidelines.
  Journal of global health · 2026 · Goldsmith S, Karim T, McIntyre S, et al.
  PMID 41860331DOI 10.7189/jogh.16.04088
• Coupling MgSO(4)-assisted SALLE with a fluorimetric turn-off strategy for the determination of cinacalcet HCl in pharmaceutical and human matrices.
  Scientific reports · 2026 · Hamad AA, Ali MAM, Chaudhary AA, et al.
  PMID 41844693DOI 10.1038/s41598-026-41887-4

The 10 most recently updated of 678 ClinicalTrials.gov registrations naming Magnesium Sulfate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Effect of Metformin, a Drug Used to Treat Diabetes, vs Placebo
  Active not recruiting · Phase 4 · Interventional · 150 enrolled · University of California, Los Angeles
  NCT05949008updated 2026-06-08
• MAGNEsium With meToprolol for Rate Control In Atrial Fibrillation
  Not yet recruiting · Phase 3 · Interventional · 196 enrolled · Wake Forest University Health Sciences
  NCT07632157updated 2026-06-08
• Biomarkers in Management of Post Partum Preeclampsia
  Not yet recruiting · Phase 4 · Interventional · 100 enrolled · Alexander Harrison
  NCT07478055updated 2026-06-01
• Intra-arterial Selective Hypothermic Magnesium Sulfate Infusion in Combination With Endovascular Thrombectomy in Acute Ischemic Stroke
  Enrolling by invitation · Phase 1 · Phase 2 · Interventional · 42 enrolled · Capital Medical University
  NCT07163299updated 2026-05-28
• Adding Magnesium Sulfate to Local Anesthetic in Combined Pectoral Nerve and Stellate Ganglion Block for Postoperative Pain Control After Modified Radical Mastectomy
  Completed · Interventional · 70 enrolled · Cairo University
  NCT06815887updated 2026-05-22
• Comparison of 1 Liter PEG With Ascorbate and Sodium Picosulfate / Magnesium Citrate for High Quality Colon Cleansing
  Completed · Phase 4 · Interventional · 1,180 enrolled · Parc de Salut Mar
  NCT04598880updated 2026-05-14
• The Relationship Between Opioid-Free Anesthesia and Postoperative Agitation-Delirium and Quality of Recovery in Pediatric Ear, Nose, and Throat Cases Monitored With Perioperative Bispectral Index
  Completed · Observational · 128 enrolled · Istanbul University - Cerrahpasa
  NCT07191652updated 2026-05-12
• Efficacy of Magnesium Sulfate Bolus in Pediatric Patients With Bronchiolitis
  Withdrawn · Phase 2 · Phase 3 · Interventional · 0 enrolled · University of Louisville
  NCT04740294updated 2026-05-11
• Ketamine + Magnesium for Chronic Cluster Headache (KETALGIA)
  Completed · Phase 4 · Interventional · 93 enrolled · University Hospital, Clermont-Ferrand
  NCT04814381updated 2026-05-08
• Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease
  Recruiting · Phase 2 · Interventional · 60 enrolled · University of British Columbia
  NCT05568498updated 2026-05-08

Frequently asked questions

How does Magnesium Sulfate work?

Mechanism-of-action classes: Acid-Base Activity; Electrolyte Activity; Enzyme Interactions.

What is Magnesium Sulfate used for?

According to FDA labeling, Magnesium Sulfate carries indications including: Uses for relief of occasional constipation (irregularity) this product generally produces bowel movement in 1/2 to 6 hours. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Magnesium Sulfate?

Magnesium Sulfate is classified as Electrolyte solutions, Magnesium, Osmotically acting laxatives, Other dermatologicals, Tests for bile duct patency, Acid-Base Activity, Electrolyte Activity, Enzyme Interactions, Atrial Repolarization, Cellular Activity Alteration, Decreased Blood Pressure, Decreased Cardiac Muscle Acetylcholine Activity, Decreased Muscular System Acetylcholine Activity, Increased GI Motility, Increased Vitamin Uptake and Modification, Small Intestine Fluid/Electrolyte Absorption Alteration, Stimulation Large Intestine Fluid/Electrolyte Absorption.

What are the brand names for Magnesium Sulfate?

Magnesium Sulfate is marketed under brand names including Concept OB, Eldertonic, Ellis Tonic, Hemocyte Plus, Sutab, Tis-U-Sol.