Magnesium Sulfate Heptahydrate
/api/v1/drug/magnesium-sulfate-heptahydrateIndications
Sourced from openFDA- Uses For relief of occasional constipation (irregularity). This product generally produces bowel movement in ½ to 6 hours.ICD-10: K59.00
Dosage & administration
Sourced from openFDADirections tbsp = tablespoon drink a full glass (8 ounces) of liquid with each dose. The dose may be taken as a single daily dose or in divided doses. do not exceed maximum daily dosage, unless directed by a doctor adults and children 12 years of age and over 10 (3/4 tbsp.) to 30 grams (2 ½ tbsps.) children 6 to under 12 years of age 5 (½ tbsp.) to 10 grams (3/4 tbsp.) children under 6 years of age consult a doctor
Warnings & precautions
Sourced from openFDADo not use laxative products for more than 1 week unless directed Ask a doctor before use if you have abdominal pain, nausea, or vomiting are present noticed a sudden change in bowel habits that persists over a period of 2 weeks kidney disease a magnesium-restricted diet Stop use and ask a doctor if rectal bleeding occurs you fail to have a bowel movement after use of a laxative. This may indicate a serious condition. If pregnant or breast-feeding ask a health professional before use. Keep this and all drugs out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Approval history
Sourced from openFDA- Sep 8, 1986NDANDA019316Fresenius Kabi Usa
- Mar 7, 2016ANDAANDA206486Fresenius Kabi Usa
- Mar 15, 2016ANDAANDA206485Fresenius Kabi Usa
- Jun 1, 2020ANDAANDA211966Baxter Hlthcare Corp
- Jul 10, 2020ANDAANDA213917Gland
- Oct 27, 2020ANDAANDA207966B Braun Medical
- Apr 26, 2021ANDAANDA207967B Braun Medical
- May 28, 2025ANDAANDA219777Aspiro
FAERS reports
- 1Drug Ineffective1,2109.1%
- 2Nausea8536.4%
- 3Off Label Use8376.3%
- 4Pyrexia7886.0%
- 5Maternal Exposure During Pregnancy7555.7%
- 6Pain7315.5%
- 7Foetal Exposure During Pregnancy6795.1%
- 8Diarrhoea6655.0%
- 9Premature Baby6615.0%
- 10Dyspnoea6044.6%
- 11Hypotension5534.2%
- 12Anaemia5524.2%
- 13Vomiting5244.0%
- 14Pneumonia4963.7%
- 15Fatigue4853.7%
Literature
Recent PubMed references pinned to Magnesium Sulfate Heptahydrate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Antenatal Magnesium Sulfate for Tocolysis and Early Enteral Feeding in Preterm Infants: A Retrospective Cohort Study.Pediatrics international : official journal of the Japan Pediatric Society · 2026 · Okuno T, Kabata D, Shimizu T, et al.PMID 42186720DOI 10.1111/ped.70446
- Sequence-Dependent Analgesic Efficacy of Ketamine and Magnesium Sulfate After Radical Nephrectomy.Medicina (Kaunas, Lithuania) · 2026 · Ladjevic NN, Dzamic Z, Jovanovic VD, et al.PMID 42075626DOI 10.3390/medicina62040754
- Protective effect of magnesium on indomethacin-induced gastric ulcer in mice.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026 · Rostami R, Eidi A, Mortazavi P, et al.PMID 42010200DOI 10.1007/s10534-026-00803-z
- 1 g/h magnesium sulfate maintenance for eclampsia prevention is enough.Acta obstetricia et gynecologica Scandinavica · 2026 · Petrecca A, Bina B, Ghi T, et al.PMID 41949178DOI 10.1111/aogs.70205
- ANESTHESIA OF MYSTERY SNAILS (POMACEA BRIDGESII) BY USING ETHANOL, EUGENOL, AND MAGNESIUM SULFATE.Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians · 2026 · Davidson A, Scagnelli A, Mans C, et al.PMID 41926251DOI 10.1638/2025-0006
- Factors associated with appropriate administration of magnesium sulfate for neuroprotection prior to early preterm birth.American journal of obstetrics & gynecology MFM · 2026 · Hendin N, Gulersen M, Blitz MJ, et al.PMID 41881424DOI 10.1016/j.ajogmf.2026.101943
- Antenatal magnesium sulphate for preterm foetal neuroprotection in low- and middle-income countries: a scoping review of research studies and guidelines.Journal of global health · 2026 · Goldsmith S, Karim T, McIntyre S, et al.PMID 41860331DOI 10.7189/jogh.16.04088
- Coupling MgSO(4)-assisted SALLE with a fluorimetric turn-off strategy for the determination of cinacalcet HCl in pharmaceutical and human matrices.Scientific reports · 2026 · Hamad AA, Ali MAM, Chaudhary AA, et al.PMID 41844693DOI 10.1038/s41598-026-41887-4
Clinical trials
The 10 most recently updated of 528 ClinicalTrials.gov registrations naming Magnesium Sulfate Heptahydrate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- MAGNEsium With meToprolol for Rate Control In Atrial FibrillationNot yet recruiting · Phase 3 · Interventional · 196 enrolled · Wake Forest University Health SciencesNCT07632157updated 2026-06-08
- Biomarkers in Management of Post Partum PreeclampsiaNot yet recruiting · Phase 4 · Interventional · 100 enrolled · Alexander HarrisonNCT07478055updated 2026-06-01
- Intra-arterial Selective Hypothermic Magnesium Sulfate Infusion in Combination With Endovascular Thrombectomy in Acute Ischemic StrokeEnrolling by invitation · Phase 1 · Phase 2 · Interventional · 42 enrolled · Capital Medical UniversityNCT07163299updated 2026-05-28
- Adding Magnesium Sulfate to Local Anesthetic in Combined Pectoral Nerve and Stellate Ganglion Block for Postoperative Pain Control After Modified Radical MastectomyCompleted · Interventional · 70 enrolled · Cairo UniversityNCT06815887updated 2026-05-22
- The Relationship Between Opioid-Free Anesthesia and Postoperative Agitation-Delirium and Quality of Recovery in Pediatric Ear, Nose, and Throat Cases Monitored With Perioperative Bispectral IndexCompleted · Observational · 128 enrolled · Istanbul University - CerrahpasaNCT07191652updated 2026-05-12
- Efficacy of Magnesium Sulfate Bolus in Pediatric Patients With BronchiolitisWithdrawn · Phase 2 · Phase 3 · Interventional · 0 enrolled · University of LouisvilleNCT04740294updated 2026-05-11
- Ketamine + Magnesium for Chronic Cluster Headache (KETALGIA)Completed · Phase 4 · Interventional · 93 enrolled · University Hospital, Clermont-FerrandNCT04814381updated 2026-05-08
- Total Intravenous Anesthesia in Patients Undergoing CraniotomyRecruiting · Interventional · 108 enrolled · Zagazig UniversityNCT07105618updated 2026-05-06
- Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA for Bariatric SurgeryRecruiting · Interventional · 70 enrolled · G.Gennimatas General HospitalNCT07568938updated 2026-05-06
- Multimodal Anesthesia in Robotic Laparoscopic NephrectomyNot yet recruiting · Interventional · 80 enrolled · Fundacio PuigvertNCT07558226updated 2026-04-30
Frequently asked questions
- What is Magnesium Sulfate Heptahydrate used for?
- According to FDA labeling, Magnesium Sulfate Heptahydrate carries indications including: Uses For relief of occasional constipation (irregularity). This product generally produces bowel movement in ½ to 6 hours.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
magnesium-sulfate-heptahydrate is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.