Methylene Chloride

• USES: • For the temporary relief of symptoms including: • headache • liver support • muscle weakness • skin irritation • poor muscle coordination These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.ICD-10: R51.9

DIRECTIONS: 1-10 drops under the tongue, 3 times a day or as directed by a health professional. Consult a physician for use in children under 12 years of age.

If pregnant or breastfeeding, ask a health professional before use. Keep out of reach of children. In case of overdose, contact a physician or Poison Control Center right away. Tamper Evident: Sealed for your protection. Do not use if seal is broken or missing.

Recent PubMed references pinned to Methylene Chloride as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Catalytic Oxidation of Dichloromethane over the Zeolitic Imidazolate Framework-Derived HZSM5@Co(3)O(4) Catalyst Synthesized through Two-Step Pyrolysis: Efficient Synergy of Acidity and Redox Properties.
  Environmental science & technology · 2026 · Su Y, Zheng Y, Wang Y, et al.
  PMID 42117574DOI 10.1021/acs.est.6c02783
• Spatially Decoupled Dual-Active Sites Break the Activity-Humidity Trade-Off: Achieving Water-Promoted Ozonation of Dichloromethane.
  Environmental science & technology · 2026 · Lin F, Li Y, Zhao Y, et al.
  PMID 41854230DOI 10.1021/acs.est.5c15703
• Enhanced bamboo charcoal-based adsorbent for dichloromethane adsorption within a wide relative humidity: Adsorption performance, moisture resistance and mechanism analysis.
  Journal of environmental sciences (China) · 2026 · Wei R, Cheng Z, Chen J, et al.
  PMID 41765507DOI 10.1016/j.jes.2025.05.027
• Rubia cordifolia L. Dichloromethane Extract Ameliorates Contrast-Induced Acute Kidney Injury by Activating Autophagy via the LC3B/p62 Axis.
  Molecules (Basel, Switzerland) · 2026 · Sun X, He K, Chen G, et al.
  PMID 41599364DOI 10.3390/molecules31020316
• Dual suppression of methanogenesis by dichloromethane and salinity: Competitive methyltransferase inhibition and energy-coupling disruption.
  Journal of hazardous materials · 2025 · Liu J, Xie S, Ji Y, et al.
  PMID 41240828DOI 10.1016/j.jhazmat.2025.140408
• The antibiofilm effects of the dichloromethane fraction of Sideroxylon obtusifolium T. D. Penn on Candida spp.
  Brazilian journal of biology = Revista brasleira de biologia · 2025 · Costa BP, Costa MMA, Melo WOS, et al.
  PMID 41172520DOI 10.1590/1519-6984.292699
• Biological autocrine signaling molecule enhanced synchronously removal of gaseous n-hexane and dichloromethane in a biotrickling filter: Performance and mechanisms.
  Journal of hazardous materials · 2025 · Lu L, Xiang Y, Ran F, et al.
  PMID 41138409DOI 10.1016/j.jhazmat.2025.140222
• Modeling reveals a metabolic basis of competition among Dehalobacter strains during tandem chloroform and dichloromethane metabolism.
  mSystems · 2025 · Bulka O, Edwards EA, Mahadevan R, et al.
  PMID 40910777DOI 10.1128/msystems.00847-25

The 10 most recently updated of 25 ClinicalTrials.gov registrations naming Methylene Chloride as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Topical Methylene Blue-Photodynamic Therapy (MB-PDT) for Burn Wound Infection
  Not yet recruiting · Early phase 1 · Interventional · 50 enrolled · University of Oklahoma
  NCT07494773updated 2026-05-19
• Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections
  Completed · Phase 3 · Interventional · 4,787 enrolled · Ondine Biomedical Inc.
  NCT06702878updated 2026-05-12
• Clinical Trial to Evaluate the Efficacy and Safety of SUBMO® as a Submucosal Injection Agent in Endoscopic Resection of Superficial Gastrointestinal Lesions.
  Not yet recruiting · Interventional · 300 enrolled · i+Med S.Coop.
  NCT07448129updated 2026-03-05
• Hormone Secretion in Transgender Males
  Withdrawn · Phase 4 · Interventional · 0 enrolled · University of California, San Diego
  NCT04321551updated 2025-01-13
• Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease
  Completed · Phase 2 · Interventional · 117 enrolled · The University of Texas Health Science Center at San Antonio
  NCT02380573updated 2024-09-19
• Clinical and Microbiologic Outcomes of aPDT in the Non-surgical Treatment of Implant Inflammation
  Completed · Phase 4 · Interventional · 56 enrolled · The University of Texas Health Science Center, Houston
  NCT04187053updated 2024-02-21
• Photodynamic in Periodontal Treatment
  Completed · Interventional · 18 enrolled · University of Sulaimani
  NCT05162417updated 2023-11-29
• The Effect of Combination Therapy of Oral MB and PRP-FG in Patients With Non-healing Diabetic Foot Ulcer
  Unknown · Early phase 1 · Interventional · 20 enrolled · Mashhad University of Medical Sciences
  NCT05850611updated 2023-10-04
• A First-in-Human Phase 1 Study of Plasmalogen Precursor PPI-1011 in Healthy Adult Volunteers to Assess Safety, Tolerability, and Pharmacokinetics
  Unknown · Phase 1 · Interventional · 56 enrolled · MED-LIFE DISCOVERIES LP
  NCT05969977updated 2023-08-01
• MOM's PAIN (Methylene Blue for Oral Mucositis' PAIN)
  Completed · Phase 2 · Interventional · 69 enrolled · M.D. Anderson Cancer Center
  NCT03469284updated 2023-04-25

Frequently asked questions

What is Methylene Chloride used for?

According to FDA labeling, Methylene Chloride carries indications including: USES: • For the temporary relief of symptoms including: • headache • liver support • muscle weakness • skin irritation • poor muscle coordination These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.