Ozone

• For the temporary relief of symptoms related to pollution such as nausea, fatigue, head discomfort and abdominal discomfort.** **These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.ICD-10: R11.2

DIRECTIONS: 1-10 drops under the tongue, 3 times a day or as directed by a health professional. Consult a physician for use in children under 12 years of age.

Keep out of reach of children. In case of overdose, contact a physician or Poison Control Center right away. If pregnant or breast-feeding, ask a health professional before use. Tamper Seal: "Sealed for Your Protection." Do not use if seal is broken or missing.

Recent PubMed references pinned to Ozone as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Maize Crops Face High Stomatal Uptake During High Exposure to Ozone in an Agroecosystem in the United States Corn Belt.
  Global change biology · 2026 · Khan AM, Hannun R, Ainsworth EA, et al.
  PMID 42247123DOI 10.1111/gcb.70952
• Ozone from wildfire plumes increases mortality.
  Science (New York, N.Y.) · 2026 · de Foy B
  PMID 42241559DOI 10.1126/science.aei2027
• Pollution Characteristics, Potential Sources and Transport Pathways of O(3) and VOCs in a Coastal City of East China.
  Bulletin of environmental contamination and toxicology · 2026 · Xue Y, Ling Y, Tong L, et al.
  PMID 42236588DOI 10.1007/s00128-026-04275-2
• Short-term ozone exposure significantly elevates paediatric respiratory disease risk in Foshan, Southern China.
  BMJ open respiratory research · 2026 · Liu Z, Ma F, Zhang Q, et al.
  PMID 42236082DOI 10.1136/bmjresp-2025-003729
• [Low-temperature plasma radiofrequency ablation of dorsal rami of spinal nerves combined with ozone injection for the treatment of lumbar facet joint disorder].
  Zhongguo gu shang = China journal of orthopaedics and traumatology · 2026 · Ding G, Zhang Y, Li Z, et al.
  PMID 42229985DOI 10.12200/j.issn.1003-0034.20250247
• Decoding the urban-suburban ozone disparities in Shandong, China: A machine learning-driven attribution analysis (2019-2023).
  Journal of environmental sciences (China) · 2026 · Zhang L, Xie H, Wang L, et al.
  PMID 42217914DOI 10.1016/j.jes.2025.12.028
• Stomatal ozone flux estimation in Mediterranean forests through sap flow analysis.
  Journal of environmental sciences (China) · 2026 · Viviano A, Tanaka R, Paoletti E, et al.
  PMID 42217902DOI 10.1016/j.jes.2025.07.006
• Future changes in ozone and oxidation capacity in China under the carbon peaking policy: The role of emissions and meteorology.
  Journal of environmental sciences (China) · 2026 · Shen A, Liu Y, Zhu Y, et al.
  PMID 42217901DOI 10.1016/j.jes.2025.12.033

The 10 most recently updated of 221 ClinicalTrials.gov registrations naming Ozone as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Ozone Therapy for Cancer Therapy-Related Oral Mucositis
  Completed · Observational · 58 enrolled · University of Pavia
  NCT07638904updated 2026-06-10
• Efficacy of Ozone Therapy in Reducing Complications Following Impacted Mandibular Third-molar Surgery
  Completed · Phase 3 · Interventional · 20 enrolled · Jelena Krunic
  NCT06802354updated 2026-06-08
• Innate Immunity in Ozone-induced Airway Inflammation in COPD
  Active not recruiting · Interventional · 72 enrolled · University of California, San Francisco
  NCT04669743updated 2026-06-04
• Ozone-therapy in Non-surgical Periodontal Therapy
  Completed · Interventional · 39 enrolled · Universita di Verona
  NCT07202312updated 2026-05-29
• Adjunctive Ozone Therapy for Residual Periodontal Pockets
  Completed · Interventional · 26 enrolled · Ataturk University
  NCT07604636updated 2026-05-22
• Macrophage Regulation of Ozone-Induced Lung Inflammation
  Recruiting · Phase 1 · Interventional · 100 enrolled · Robert Tighe, MD
  NCT05773001updated 2026-05-15
• The Effect of Ozone on Salivary Flow in Patients With Xerostomia and Hyposalivation After Radiotherapy (OZONEXEROSTOMI)
  Not yet recruiting · Interventional · 100 enrolled · University of Brasilia
  NCT07571356updated 2026-05-06
• Ozone Oil-based Gel and CHX Gel After Lower Third Molar Removal
  Active not recruiting · Early phase 1 · Interventional · 100 enrolled · Cairo University
  NCT07549672updated 2026-04-28
• Ozone Therapy After Open Flap Debridement in Periodontitis
  Completed · Interventional · 24 enrolled · Alparslan Dilsiz
  NCT07551297updated 2026-04-24
• COMPARISON BETWEEN DIFFERENT CONCENTRATIONS OF OZONE GAS AS AN INTRA-ARTICULAR INJECTION FOR TREATMENT OF INTERNAL DERANGEMENT OF TEMPROMANDIBULAR JOINT
  Completed · Interventional · 20 enrolled · Alexandria University
  NCT07523451updated 2026-04-13

Frequently asked questions

What is Ozone used for?

According to FDA labeling, Ozone carries indications including: For the temporary relief of symptoms related to pollution such as nausea, fatigue, head discomfort and abdominal discomfort.** **These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.