Propionate
/api/v1/drug/propionateIndications
Sourced from openFDA- Uses Temporarily relieves these symptoms of hay fever or other upper respiratory allergies: nasal congestion itchy, watery eyes itchy nose runny nose sneezing
Dosage & administration
Sourced from openFDADirections read the Quick Start Guide for how to: prime the bottle use the spray clean the spray nozzle shake gently before each use use this product only once a day do not use more than directed ADULTS AND CHILDREN 12 YEARS OF AGE AND OLDER Week 1- use 2 sprays in each nostril once daily Week 2 through 6 months- use 1 or 2 sprays in each nostril once daily, as needed to treat your symptoms After 6 months of daily use – ask your doctor if you can keep using CHILDREN 4 TO 11 YEARS OF AGE the growth rate of some children may be slower while using this product. Children should use for the shortest amount of time necessary to achieve symptom relief. Talk to your child’s doctor if your child needs to use the spray for longer than two months a year. an adult should supervise use use 1 spray in each nostril once daily CHILDREN UNDER 4 YEARS OF AGE do not use
Warnings & precautions
Sourced from openFDAOnly for use in the nose. Do not spray into your eyes or mouth.
Approval history
Sourced from openFDA- Aug 24, 2000NDANDA021077Glaxo Grp Ltd
- Sep 29, 2000NDANDA020833Glaxo Grp Ltd
- Jul 24, 2003NDANDA021535Galderma Labs Lp
- Feb 5, 2004NDANDA021644Galderma Labs
- May 14, 2004NDANDA021433Glaxo Grp Ltd
- Oct 27, 2005NDANDA021835Galderma Labs Lp
- Jun 8, 2006NDANDA021254Glaxo Grp Ltd
- May 1, 2012NDANDA202236Mylan Speciality Lp
FAERS reports
- 1Dyspnoea21,84311%
- 2Drug Ineffective18,9579.5%
- 3Asthma12,6626.3%
- 4Cough11,3895.7%
- 5Fatigue11,3475.7%
- 6Headache10,8585.4%
- 7Pneumonia10,0825.0%
- 8Nausea9,3594.7%
- 9Off Label Use8,9534.5%
- 10Pain8,8374.4%
- 11Malaise7,9584.0%
- 12Diarrhoea7,7593.9%
- 13Dizziness7,2513.6%
- 14Product Dose Omission Issue6,6283.3%
- 15Wheezing6,4533.2%
Literature
Recent PubMed references pinned to Propionate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Efficacy and Safety of Clascoterone Cream 1% and Clindamycin 1.2%/Benzoyl Peroxide 5% Gel Treatment in Patients With Acne.Journal of drugs in dermatology : JDD · 2026 · Kircik C, Kircik L, Squittieri N, et al.PMID 42235046DOI 10.36849/JDD.9745
- Ciprofol-Esketamine Versus Ciprofol-Remifentanil in Hysteroscopic Endometrial Polypectomy: A Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2026 · Zhang Z, Wang Z, Gong W, et al.PMID 42226428DOI 10.12659/MSM.952468
- 3-Nitropropionic Acid-Induced Huntington's Disease in Preclinical Models: Mechanisms, Peripheral Toxicities, Model Gaps, and Future Directions.Molecular neurobiology · 2026 · Dontiboina HR, Yadava S, Nakka VP, et al.PMID 42217109DOI 10.1007/s12035-026-05967-w
- Radiolysis Derivatives from p-Coumaric Acid via Gamma Irradiation and Their Anti-Inflammatory Activities.Molecules (Basel, Switzerland) · 2026 · Han AR, Song HY, Jeong GH, et al.PMID 42197184DOI 10.3390/molecules31101630
- Respiratory Depression Following Concomitant Infusion of Remimazolam and Remifentanil Using Targeted Effect-Site Concentrations: A Randomized Controlled Trial.Medicina (Kaunas, Lithuania) · 2026 · Kim HY, Min SK, Moon JH, et al.PMID 42195193DOI 10.3390/medicina62050940
- Chemo-enzymatic synthesis of G1-monoacrylate and derived amphiphiles with β-thiopropionate ester linker for drug delivery applications.Bioorganic & medicinal chemistry letters · 2026 · Kumari P, Kumar SPMID 42167551DOI 10.1016/j.bmcl.2026.130691
- Rescue of astrocytic ASCT1 expression and d-serine uptake attenuates remifentanil-induced hyperalgesia.Biochemical and biophysical research communications · 2026 · Chen C, Shi Y, Wan Y, et al.PMID 42161059DOI 10.1016/j.bbrc.2026.153944
- Branched-chain amino acids alleviate Parkinson's neurodegeneration via microbial propionate-dependent restoration of the PI3K/Akt/mTORC1 axis.Molecular immunology · 2026 · Mi N, Ma L, Zhao J, et al.PMID 42160868DOI 10.1016/j.molimm.2026.05.003
Clinical trials
The 10 most recently updated of 1,173 ClinicalTrials.gov registrations naming Propionate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Influence of Dermocorticoids on Bone Mineral Density in Patients With Bullous PemphigoidCompleted · Phase 4 · Interventional · 47 enrolled · Centre Hospitalier Universitaire, AmiensNCT03926377updated 2026-06-12
- Comparison of the Efficacy of Clobetasol Propionate 0.05% Mouthwash, Photobiomodulation, and Their Combination in Managing of Oral Lesions in Patient With Pemphigus Vulgaris.Recruiting · Interventional · 30 enrolled · Damascus UniversityNCT07641725updated 2026-06-11
- A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma ExacerbationsActive not recruiting · Phase 3 · Interventional · 2,772 enrolled · Teva Branded Pharmaceutical Products R&D LLCNCT06052267updated 2026-06-11
- Sedation Methods in Percutaneous Transhepatic Biliary Drainage: Procedure Quality and RecoveryRecruiting · Interventional · 98 enrolled · Ankara City Hospital BilkentNCT07640243updated 2026-06-10
- BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)Recruiting · Phase 2 · Interventional · 45 enrolled · Dana-Farber Cancer InstituteNCT05922761updated 2026-06-10
- Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate CancerRecruiting · Phase 1 · Interventional · 14 enrolled · Roswell Park Cancer InstituteNCT06305598updated 2026-06-10
- Thread Embedding Acupuncture For Rhinitis AllergyCompleted · Interventional · 64 enrolled · University of Medicine and Pharmacy at Ho Chi Minh CityNCT06858137updated 2026-06-09
- Using a Contact Dermatitis Model With Biologic Medications to Study Skin InflammationActive not recruiting · Phase 2 · Phase 3 · Interventional · 45 enrolled · Wei-Che KoNCT05535738updated 2026-06-09
- A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With AsthmaRecruiting · Phase 3 · Interventional · 724 enrolled · Teva Branded Pharmaceutical Products R&D LLCNCT06664619updated 2026-06-08
- Minimal Flow Anesthesia and Infection RiskCompleted · Interventional · 140 enrolled · Ankara City Hospital BilkentNCT07092046updated 2026-06-05
Frequently asked questions
- What is Propionate used for?
- According to FDA labeling, Propionate carries indications including: Uses Temporarily relieves these symptoms of hay fever or other upper respiratory allergies: nasal congestion itchy, watery eyes itchy nose runny nose sneezing. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
propionate is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.