Psyllium

Mechanism-of-action class: Stool Bulking Activity.

• Use For relief of occasional constipation (regularity)ICD-10: K59.00

Directions Put one dose into an empty glass. Mix this product (child or adult dose) with at least 8 ounces (a full glass) of water or other fluid. Taking this product without enough liquid may cause choking. See choking warning. Stir briskly and drink promptly. If mixture thickens, add more liquid. Adults 12 Years and older: 1 rounded TEASPOON into an 8 oz of liquid at the first sign of irregularity. Can be taken up to 3 times daily. Generally produces effect in 12-72 hours. Children under 12 years: Consult a doctor before use. Bulk-forming fibers like Psyllium husk may affect how well other medicines work, If you are taking a prescription medicine by mouth, take this product at least 2 hours before or after the prescribed medicine. As your body adjusts to increased fiber intake, you may experience changes in bowel habits or minor bloating. NEW USERS Start with 1 serving per day; gradually increase to desired daily intake. You may initially experience changes in bowel habits or minor bloating as your body adjusts to increased fiber intake. Keep Out of Reach of Children

Choking: Taking this product without adequate fluid may cause it to swell and block your throat or esophagus and may cause choking. Do not take this product, if you have difficulty in swallowing. If you experience chest pain, vomiting or difficulty in swallowing or breathing after taking this product, seek immediate medical attention. Allergy alert: This product may cause an allergic reaction in people sensitive to inhaled or ingested psyllium. Safety Warning TAMPER-EVIDENT: DO NOT USE IF PRINTED SEAL UNDER CAP IS TORN OR MISSING

1. 1Fatigue1,04411%
2. 2Diarrhoea99110%
3. 3Constipation8749.1%
4. 4Off Label Use8018.4%
5. 5Nausea7077.4%
6. 6Headache6777.1%
7. 7Drug Ineffective6636.9%
8. 8Pain6446.7%
9. 9Dyspnoea5695.9%
10. 10Asthenia5005.2%
11. 11Dizziness4815.0%
12. 12Rash4464.7%
13. 13Fall4414.6%
14. 14Weight Decreased4044.2%
15. 15Arthralgia3974.1%

Recent PubMed references pinned to Psyllium as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• A pilot feasibility study of nurse-led psyllium supplementation for metabolic health in hospitalized patients with schizophrenia.
  Archives of psychiatric nursing · 2026 · Jang RS, Yang CC, Yen WJ, et al.
  PMID 41956574DOI 10.1016/j.apnu.2026.152072
• Encapsulation of Plant Extracts in a Psyllium/Starch Matrix: Synthesis and Functional Properties.
  Molecules (Basel, Switzerland) · 2026 · Krystyjan M, Khachatryan G, Khachatryan K, et al.
  PMID 41900125DOI 10.3390/molecules31061026
• Evaluating the additive effects of psyllium husk powder combined with micronized cold-pressed hemp seed cake on the quality profile and in vitro digestibility of reduced-phosphate frankfurters.
  Meat science · 2026 · Zhao J, Yao X, Ma Y, et al.
  PMID 41762771DOI 10.1016/j.meatsci.2026.110075
• A randomised, placebo-controlled trial in healthy humans of modified cellulose or psyllium evaluating the role of gelation in altering colonic gas production during inulin co-administration.
  Food & function · 2026 · Reid JESJ, Alhasani AT, MacCalman T, et al.
  PMID 41636227DOI 10.1039/d5fo03532e
• A psyllium-supplemented gastrointestinal diet is effective for the management of chronic constipation in cats: a 6-month controlled clinical trial.
  Journal of feline medicine and surgery · 2026 · Rochon J, Charles H, Biourge V, et al.
  PMID 41631677DOI 10.1177/1098612X261420519
• An effective approach for Coomassie brilliant blue R-250 removal using psyllium - gum ghatti based smart material.
  International journal of biological macromolecules · 2026 · Chandrajkrishna C, Sharma H, Saksham, et al.
  PMID 41539510DOI 10.1016/j.ijbiomac.2026.150263
• Magnetically modified amino MXene psyllium hydrogel nanobiosorbent for the simultaneous removal of hexavalent chromium and curcumin from wastewater.
  Scientific reports · 2025 · Abouelanwar ME, Mahmoud ME
  PMID 41461876DOI 10.1038/s41598-025-32138-z
• Smart biopolymer gels based on psyllium-alginate-cerium oxide nanoparticles with multifunctional properties.
  International journal of biological macromolecules · 2026 · Orhan B, Torlak E, Kaygusuz H, et al.
  PMID 41412244DOI 10.1016/j.ijbiomac.2025.149732

The 10 most recently updated of 130 ClinicalTrials.gov registrations naming Psyllium as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Effect of Alpha Tocopherol and Psyllium on Lipid Levels in Dyslipidaemia Patients
  Completed · Phase 2 · Interventional · 60 enrolled · NUR International University
  NCT07610304updated 2026-05-27
• Psyllium in Pediatric IBS
  Recruiting · Phase 2 · Interventional · 110 enrolled · Dr Bruno Chumpitazi, M.D.
  NCT06639984updated 2026-05-26
• Bowel Dysfunction After Low Rectal Resection. An Pilot Study Using Psyllium Husk In Rectal Cancer Patients.
  Completed · Interventional · 24 enrolled · Sykehuset Telemark
  NCT06724198updated 2026-05-11
• Clinical Outcomes and Patient Satisfaction With Velnez Versus Nasopore in Nasal Surgery
  Completed · Interventional · 20 enrolled · Ayu, Inc.
  NCT07560254updated 2026-05-06
• Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance
  Recruiting · Phase 3 · Interventional · 140 enrolled · University Hospital, Basel, Switzerland
  NCT06936774updated 2026-05-06
• WISH, Feasibility of a Factorial Design
  Completed · Interventional · 18 enrolled · The University of Tennessee, Knoxville
  NCT07023822updated 2026-05-05
• Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV
  Not yet recruiting · Phase 4 · Interventional · 62 enrolled · Albert Einstein College of Medicine
  NCT07526948updated 2026-04-14
• A Study to Prevent and Improve Sexual Health Concerns for People With Breast Cancer
  Recruiting · Interventional · 50 enrolled · Memorial Sloan Kettering Cancer Center
  NCT05910294updated 2026-04-01
• Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
  Recruiting · Interventional · 25 enrolled · Federal University of Minas Gerais
  NCT07202481updated 2026-03-24
• Exploring Mechanism of Action of Dietary Fibre on the Gut Microbiota and Metabolites
  Completed · Interventional · 40 enrolled · University of Aberdeen
  NCT05906589updated 2026-02-12

Frequently asked questions

How does Psyllium work?

Mechanism-of-action class: Stool Bulking Activity.

What is Psyllium used for?

According to FDA labeling, Psyllium carries indications including: Use For relief of occasional constipation (regularity). This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Psyllium?

Psyllium is classified as Stool Bulking Activity, Increased Large Intestinal Motility, Inhibition Large Intestine Fluid/Electrolyte Absorption.

What are the brand names for Psyllium?

Psyllium is marketed under brand names including Hydrocil, Konsyl, Metamucil, Mucilin, Reguloid, Wal-Mucil.