Radium
US-FDASourced from openFDA
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/api/v1/drug/radiumIndications
Sourced from openFDA- Uses: See symptoms on front panel.
Dosage & administration
Sourced from openFDAAdults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor.
Approval history
Sourced from openFDA- May 15, 2013NDANDA203971Bayer Hlthcare
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
6,977 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Prostatic Specific Antigen Increased4756.8%
- 2Death4646.7%
- 3Fatigue4456.4%
- 4Hormone-refractory Prostate Cancer4356.2%
- 5Nausea3885.6%
- 6Pain3645.2%
- 7Diarrhoea3434.9%
- 8Metastases To Bone3244.6%
- 9General Physical Health Deterioration3124.5%
- 10Anaemia2914.2%
- 11Asthenia2804.0%
- 12Malaise2703.9%
- 13Haemoglobin Decreased2473.5%
- 14Disease Progression2253.2%
- 15Prostate Cancer2193.1%
Literature
Recent PubMed references pinned to Radium as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Radium-226 bioaccumulation and toxicity in the great pond snail Lymnaea stagnalis.Aquatic toxicology (Amsterdam, Netherlands) · 2026 · Guimard L, Racine K, Fortin C, et al.PMID 42085866DOI 10.1016/j.aquatox.2026.107832
- Radium recovery from mining tailings: A comprehensive review of techniques and applications.Journal of environmental radioactivity · 2026 · Galvis OCG, Goulart de Araujo L, Vicente R, et al.PMID 42054870DOI 10.1016/j.jenvrad.2026.108010
- Evaluation of chromatographic resins for high efficacy separation of radium from chemical analogues.Journal of chromatography. A · 2026 · Coupannec M, Kmak KN, Despotopulos JD, et al.PMID 42030654DOI 10.1016/j.chroma.2026.467004
- LuRa: Efficacy and Safety of Radium-223 Following [(177)Lu]Lu-PSMA-617 in Patients With Metastatic Castration-Resistant Prostate Cancer.Clinical genitourinary cancer · 2026 · Zarka J, Juthani R, Sartor O, et al.PMID 41997765DOI 10.1016/j.clgc.2026.102552
- Updated ICRP dosimetry amplifies limitations of WHO adult-based radium screening: implications for early-life and lifetime exposure.Journal of environmental radioactivity · 2026 · Alnajjar A, Hawwari MPMID 41996842DOI 10.1016/j.jenvrad.2026.107990
- Identifying age-specific windows of vulnerability: a lifetime dose assessment of Ra-226 in drinking water.Journal of radiological protection : official journal of the Society for Radiological Protection · 2026 · Alnajjar A, Hawwari MPMID 41974138DOI 10.1088/1361-6498/ae5e7f
- Analytical approach for (226)Ra, (228)Ra and (210)Pb measurements for environmental monitoring using liquid scintillation spectrometry.Journal of environmental radioactivity · 2026 · Medrado HHS, Dos Santos VA, Porto JAM, et al.PMID 41962505DOI 10.1016/j.jenvrad.2026.107988
- The activity concentration of (226,228)Ra, (234,238)U, and (40)K isotopes in the different types of phosphate mineral fertilizers and the associated radiological risk.Environmental geochemistry and health · 2026 · Walencik-Łata A, Szkliniarz KPMID 41945176DOI 10.1007/s10653-026-03170-3
Clinical trials
The 10 most recently updated of 99 ClinicalTrials.gov registrations naming Radium as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive to Hormonal TherapyRecruiting · Phase 1 · Phase 2 · Interventional · 90 enrolled · National Cancer Institute (NCI)NCT04071236updated 2026-06-11
- Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the BonesActive not recruiting · Phase 2 · Interventional · 70 enrolled · National Cancer Institute (NCI)NCT04090398updated 2026-06-11
- Testing the Safety of Different Doses of Olaparib Given Radium-223 for Men With Advanced Prostate Cancer With Bone MetastasisActive not recruiting · Phase 1 · Phase 2 · Interventional · 132 enrolled · National Cancer Institute (NCI)NCT03317392updated 2026-06-11
- RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs, Androgen Receptor Pathway Inhibitors) in Patients With Prostate Cancer That Has Spread to the Bones (mCRPC, Metastatic Castration-Resistant Prostate Cancer)Active not recruiting · Phase 4 · Interventional · 654 enrolled · BayerNCT04597125updated 2026-06-08
- Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic, Castration-Resistant Prostate CancerActive not recruiting · Phase 2 · Interventional · 30 enrolled · University of Southern CaliforniaNCT03344211updated 2026-06-03
- Study of Nivolumab in Combination w Radium-223 in Men w Metastatic Castration Resistant Prostate CancerActive not recruiting · Phase 1 · Interventional · 39 enrolled · University of UtahNCT04109729updated 2026-06-01
- AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)Recruiting · Phase 3 · Interventional · 670 enrolled · AstraZenecaNCT07611110updated 2026-05-28
- Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL StudyActive not recruiting · Phase 2 · Interventional · 134 enrolled · National Cancer Institute (NCI)NCT04071223updated 2026-05-13
- A Study of Stereotactic Body Radiation Therapy and Radium (Ra-223) Dichloride in Prostate Cancer That Has Spread to the BonesCompleted · Phase 2 · Interventional · 12 enrolled · Memorial Sloan Kettering Cancer CenterNCT05133440updated 2026-04-28
- Radium Ra 223 Dichloride, Hormone Therapy and Stereotactic Body Radiation Therapy in Treating Patients With Metastatic Prostate CancerActive not recruiting · Phase 2 · Interventional · 25 enrolled · City of Hope Medical CenterNCT03361735updated 2026-04-09
Frequently asked questions
- What is Radium used for?
- According to FDA labeling, Radium carries indications including: Uses: See symptoms on front panel.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What are the brand names for Radium?
- Radium is marketed under brand names including Xofigo.
Note. Data for
radium is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.