pharmacopeia
GET
/api/v1/drug/ranitidine

Mechanism of action

Sourced from openFDA

Mechanism-of-action class: Histamine H2 Receptor Antagonists.

Histamine H2 Receptor

Indications

Sourced from openFDA
  • Use(s) relieves heartburn associated with acid indigestion and sour stomach prevents heartburn associated with acid indigestion and sour stomach brought on by eating or drinking certain foods and beverages

Dosage & administration

Sourced from openFDA

Directions adults and children 12 years and over: to relieve symptoms, swallow 1 tablet with a glass of water to prevent symptoms, swallow 1 tablet with a glass of water 30 to 60 minutes before eating food or drinking beverages that cause heartburn can be used up to twice daily (do not take more than 2 tablets in 24 hours) children under 12 years: ask a doctor

Warnings & precautions

Sourced from openFDA

Allergy alert: Do not use if you are allergic to ranitidine or other acid reducers Do not use if you have trouble or pain swallowing food, vomiting with blood, or bloody or black stools.These may be signs of a serious condition. See your doctor. with other acid reducers Ask a doctor before use if you have had heartburn over 3 months. This may be a sign of a more serious condition. heartburn with lightheadedness, sweating or dizziness chest pain or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck or shoulders; or lightheadedness frequent chest pain frequent wheezing, particularly with heartburn unexplained weight loss nausea or vomiting stomach pain kidney disease Ask a doctor or pharmacist before use if you are • taking a prescription drug. Acid reducers may interact with certain prescription drugs. Stop use and ask doctor if your heartburn continues or worsens you need to take this product for more than 14 days If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Approval history

Sourced from openFDA
  • Mar 28, 2000ANDAANDA075294Dr Reddys Labs Ltd
  • Nov 29, 2000ANDAANDA075742Dr Reddys Labs Ltd
  • Oct 13, 2006ANDAANDA077824Amneal Pharms Ny
  • Aug 31, 2007ANDAANDA078192Dr Reddys Labs Ltd
  • Sep 21, 2007ANDAANDA077405Pharm Assoc
  • Feb 29, 2012ANDAANDA201745Strides Pharma
  • Aug 20, 2018ANDAANDA210243Granules
  • Sep 27, 2018ANDAANDA209859Ajanta Pharma Ltd

FAERS reports

View JSON
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
230,511 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
  1. 1Breast Cancer29,41313%
  2. 2Prostate Cancer26,44611%
  3. 3Colorectal Cancer20,7209.0%
  4. 4Bladder Cancer19,2078.3%
  5. 5Renal Cancer19,0358.3%
  6. 6Oesophageal Carcinoma11,0664.8%
  7. 7Incorrect Dose Administered9,7424.2%
  8. 8Hepatic Cancer8,8343.8%
  9. 9Gastric Cancer8,7423.8%
  10. 10Pancreatic Carcinoma8,0373.5%
  11. 11Lung Neoplasm Malignant7,9523.4%
  12. 12Nausea5,4362.4%
  13. 13Fatigue5,2432.3%
  14. 14Drug Ineffective5,0732.2%
  15. 15Chronic Kidney Disease4,9782.2%

Literature

View JSON

Recent PubMed references pinned to Ranitidine as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

Clinical trials

View JSON

The 10 most recently updated of 110 ClinicalTrials.gov registrations naming Ranitidine as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

Frequently asked questions

How does Ranitidine work?
Mechanism-of-action class: Histamine H2 Receptor Antagonists.
What is Ranitidine used for?
According to FDA labeling, Ranitidine carries indications including: Use(s) relieves heartburn associated with acid indigestion and sour stomach prevents heartburn associated with acid indigestion and sour stomach brought on by eating or drinking certain foods and beverages. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
What class of drug is Ranitidine?
Ranitidine is classified as H2-receptor antagonists, Histamine-2 Receptor Antagonist, Histamine H2 Receptor Antagonists, Decreased Histamine Activity, Inhibition Gastric Acid Secretion.
What are the brand names for Ranitidine?
Ranitidine is marketed under brand names including Zantac.
Note. Data for ranitidine is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.

Search pharmacopeia

Search drugs, classes, and ingredients