Santonin
US-FDASourced from openFDA
GET
/api/v1/drug/santoninIndications
Sourced from openFDA- Nervousness, irritability, sleeplessness in children*
Dosage & administration
Sourced from openFDAAdults and children: At the onset of symptoms, dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a doctor.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
1 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Chest Pain1100%
- 2Diarrhoea1100%
- 3Dyspepsia1100%
- 4Headache1100%
- 5Influenza Like Illness1100%
- 6Musculoskeletal Pain1100%
- 7Myalgia1100%
- 8Pain In Jaw1100%
Literature
Recent PubMed references pinned to Santonin as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Santonin attenuates Ovalbumin-induced airway inflammation by inhibiting IL-4/IL-13 signaling.Biochemical and biophysical research communications · 2025 · Noor R, Naz S, Khan JZ, et al.PMID 40616980DOI 10.1016/j.bbrc.2025.152284
- New ψ-Santonin Derivatives from Crossostephium chinense and Their Anti-Proliferative Activities against Leishmania major and Human Cancer Cells A549.Molecules (Basel, Switzerland) · 2023 · Wang Z, Yamano Y, Kawakami S, et al.PMID 38138604DOI 10.3390/molecules28248108
- Identification of the Toxic Compounds in Camellia oleifera Honey and Pollen to Honey Bees (Apis mellifera).Journal of agricultural and food chemistry · 2022 · Li Z, Huang Q, Zheng Y, et al.PMID 36214176DOI 10.1021/acs.jafc.2c04950
- Pharmacological Evaluation of Artemisia cina Crude CO(2) Subcritical Extract after the Removal of Santonin by Means of High Speed Countercurrent Chromatography.Molecules (Basel, Switzerland) · 2020 · Sakipova Z, Giorno TBS, Bekezhanova T, et al.PMID 32545512DOI 10.3390/molecules25122728
- The Effects of (11R)-13-(6-Nitroindazole)-11,13-Dihydroludartin on Human Prostate Carcinoma Cells and Mouse Tumor Xenografts.Medical science monitor : international medical journal of experimental and clinical research · 2020 · Wang L, Wang L, Wei S, et al.PMID 32036379DOI 10.12659/MSM.920389
- Transformation of Santonin to a Naproxen Analogue with Anti-Inflammatory Activity.Journal of natural products · 2019 · Singh R, Mandrah K, Asati A, et al.PMID 31125226DOI 10.1021/acs.jnatprod.8b00318
- Naturally Occurring Sesquiterpene Lactone-Santonin, Exerts Anticancer Effects in Multi-Drug Resistant Breast Cancer Cells by Inducing Mitochondrial Mediated Apoptosis, Caspase Activation, Cell Cycle Arrest, and by Targeting Ras/Raf/MEK/ERK Signaling Pathway.Medical science monitor : international medical journal of experimental and clinical research · 2019 · Wu Z, Wang C, Huang M, et al.PMID 31101800DOI 10.12659/MSM.915246
- Structure-activity relationship and synthetic methodologies of α-santonin derivatives with diverse bioactivities: A mini-review.European journal of medicinal chemistry · 2019 · Wang J, Su S, Zhang S, et al.PMID 31082765DOI 10.1016/j.ejmech.2019.04.066
Frequently asked questions
- What is Santonin used for?
- According to FDA labeling, Santonin carries indications including: Nervousness, irritability, sleeplessness in children*. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
Note. Data for
santonin is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.