Silicon Dioxide
US-FDASourced from openFDA
GET
/api/v1/drug/silicon-dioxideIndications
Sourced from openFDA- USE: Condition listed above or as directed by a physician.
Dosage & administration
Sourced from openFDADIRECTIONS: (adults/children) Dissolve 5 pellets under the tongue 3 times a day until symptoms are relieved or as directed by a physician.
Warnings & precautions
Sourced from openFDAStop use and ask a physician if symptoms persist for more than 3 days or worsen.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
1,068 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Death969.0%
- 2Pain787.3%
- 3Nausea696.5%
- 4Diarrhoea646.0%
- 5Pain In Extremity625.8%
- 6Fatigue615.7%
- 7Headache575.3%
- 8Drug Ineffective535.0%
- 9Rash494.6%
- 10Arthralgia454.2%
- 11Asthenia434.0%
- 12Dizziness393.7%
- 13Malaise393.7%
- 14Dyspnoea373.5%
- 15Vomiting363.4%
Literature
Recent PubMed references pinned to Silicon Dioxide as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- In vitro antitumor efficacy of hyaluronic acid coating for curcumin-loaded zeolitic imidazole frameworks-8 (ZIF-8) versus that of uncoated curcumin-loaded ZIF-8 nanocomposites.Scientific reports · 2026 · Oransa WW, Zahran RF, El Sadda RR, et al.PMID 42252331DOI 10.1038/s41598-026-48707-9
- Controlled Glutathione-Releasing Multifunctional Gelatin Methacryloyl/Chitosan/Zeolite Hydrogels for Accelerated Regeneration in Diabetic Wounds.Journal of biomedical materials research. Part A · 2026 · Kabadas FB, Bedir T, Ilhan E, et al.PMID 42237728DOI 10.1002/jbm.a.70101
- Synthesis, Characterization, and Antibacterial Properties of Silver, Copper, and Ag/Cu Bimetallic Nanoparticles Supported on Organically Modified Bentonite.ChemPlusChem · 2026 · Cherifi Z, Derdar H, Radi MA, et al.PMID 42237719DOI 10.1002/cplu.70187
- Minute-Scale Adsorption of Diverse Marine Viruses Onto Clay Minerals.Environmental microbiology · 2026 · Cai L, Tian Y, Qiu X, et al.PMID 42236122DOI 10.1111/1462-2920.70348
- Study on heavy metal pollution and spatial distribution characteristics of soil in granite hilly slope land: a case study of Huayuan Town, Xiangxi, Hunan, China.Environmental geochemistry and health · 2026 · Zhou B, Ren B, Deng X, et al.PMID 42234201DOI 10.1007/s10653-026-03271-z
- Bone Healing Response of Two Different Silicate-Containing Calcium Phosphate Synthetic Bone Grafts in a Rabbit Femoral Critical-Sized Defect Model.Journal of biomedical materials research. Part B, Applied biomaterials · 2026 · Gibson IR, Conway JC, Lopes VR, et al.PMID 42231723DOI 10.1002/jbm.b.70103
- Moisture-driven local strain development in ASR-damaged concrete.PloS one · 2026 · Azad S, Trtik P, Strobl M, et al.PMID 42224338DOI 10.1371/journal.pone.0347208
- Microbiologically influenced corrosion (MIC) potential of bentonite microorganisms: implications for a deep geological repository for nuclear waste.World journal of microbiology & biotechnology · 2026 · Černá K, Mukhtar SS, Bureš R, et al.PMID 42223820DOI 10.1007/s11274-026-05039-0
Clinical trials
The 10 most recently updated of 418 ClinicalTrials.gov registrations naming Silicon Dioxide as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- An Initial Investigation Into the Effects of β-Alanine on Performance and Physiological Responses During Simulated Wrestling MatchesActive not recruiting · Interventional · 16 enrolled · China Medical University HospitalNCT07641907updated 2026-06-11
- A Novel Cold and Flu Herbal Blend for Reducing the Duration and Severity of the Common ColdNot yet recruiting · Phase 2 · Interventional · 300 enrolled · RDC Clinical Pty LtdNCT07642648updated 2026-06-11
- The Use of Nanoparticles to Guide the Surgical Treatment of Prostate CancerRecruiting · Phase 1 · Interventional · 16 enrolled · Memorial Sloan Kettering Cancer CenterNCT04167969updated 2026-06-10
- PI-YSP-0111 Formulation on Human Gut Microbiota and Body CompositionRecruiting · Interventional · 140 enrolled · Taipei Medical UniversityNCT07618000updated 2026-06-01
- Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)Recruiting · Phase 1 · Phase 2 · Interventional · 50 enrolled · Exegi Pharma, LLCNCT05938465updated 2026-05-28
- Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected ImplantsEnrolling by invitation · Interventional · 90 enrolled · Andrea RavidaNCT06430268updated 2026-05-18
- Cabozantinib for Patients With Recurrent or Progressive MeningiomaRecruiting · Phase 2 · Interventional · 24 enrolled · Baptist Health South FloridaNCT05425004updated 2026-05-14
- Evaluation of the Effect of the Toothpaste on Delicate GumsRecruiting · Interventional · 60 enrolled · Lacer S.A.NCT07494747updated 2026-05-14
- Clinical Evaluation of the Antidepressant Effect of the Use of Probiotics in Bipolar DisorderCompleted · Interventional · 141 enrolled · University of Sao PauloNCT05762887updated 2026-05-13
- Safety and Tolerance of a Novel Three-Strain Probiotic in Healthy AdultsActive not recruiting · Interventional · 30 enrolled · Pendulum TherapeuticsNCT07566884updated 2026-05-11
Frequently asked questions
- What is Silicon Dioxide used for?
- According to FDA labeling, Silicon Dioxide carries indications including: USE: Condition listed above or as directed by a physician.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
Note. Data for
silicon-dioxide is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.