pharmacopeia
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/api/v1/drug/silver-nitrate

Mechanism of action

Sourced from openFDA

Mechanism-of-action class: Protein Synthesis Inhibitors.

Protein Synthesis

Indications

Sourced from openFDA
  • INDICATIONS: For cauterization of skin or mucous membrane and for removing warts and granulated tissue.

Contraindications

Sourced from openFDA
  • Silver salts stain tissue black due to deposition of reduced silver. The stain gradually disappears within a period of two weeks.contraindicated

Dosage & administration

Sourced from openFDA

Moisten the applicator tip with distilled, deionized or purified water and apply the silver nitrate to the affected area by holding, rubbing, or rotating the tip along the affected tissue. The strength of the action is controlled by the dilution with distilled, deionized or purified water. One silver nitrate applicator is generally sufficient for each application. The action of the silver nitrate can be stopped by washing the area with saline solution (0.9% sodium chloride). Using saline solution to wet the applicator tips, or residual saline from wound flushing/washing will interfere with the action of silver nitrate resulting in cauterization failure. Only use distilled, deionized or purified water to wet applicator tips. Blot dry wounds that have been flushed/washed with saline prior to applying silver nitrate.

Warnings & precautions

Sourced from openFDA

WARNING: KEEP OUT OF REACH OF CHILDREN. The active ingredients are poisonous and may be fatal when ingested in sufficient doses. The symptoms include toxic gastroenteritis, which may lead to coma, convulsion, paralysis and profound alteration of respiration. If poisoning occurs, immediately consult a physician. WARNING: DO NOT USE ON THE EYES. In case of eye contact, hold eyes open and immediately flush thoroughly with water for at least 15 minutes and consult a physician. CAUTION: SILVER NITRATE IS A CAUSTIC SUBSTANCE. Chemical burns may result from inappropriate use of product. • Wear chemical resistant gloves while using this product. Wear other appropriate personal protective equipment as needed. • Take care to confine the silver nitrate to the area being treated by using an appropriate physical or chemical barrier to prevent staining or burning of untreated tissue. • Skin contact time with applicators should be minimal when used on thin delicate skin or neonates. • Avoid prolonged contact with skin or other surfaces since staining may occur. CAUTION: FEDERAL LAW PROHIBITS DISPENSING WITHOUT PRESCRIPTION.

FAERS reports

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Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
738 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
  1. 1Diarrhoea567.6%
  2. 2Fatigue567.6%
  3. 3Pain496.6%
  4. 4Drug Ineffective425.7%
  5. 5Arthralgia405.4%
  6. 6Nausea405.4%
  7. 7Dizziness375.0%
  8. 8Headache375.0%
  9. 9Fall354.7%
  10. 10Gait Disturbance334.5%
  11. 11Muscle Spasms314.2%
  12. 12Dyspnoea304.1%
  13. 13Vomiting304.1%
  14. 14Feeling Abnormal283.8%
  15. 15Off Label Use283.8%

Literature

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Recent PubMed references pinned to Silver Nitrate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

Clinical trials

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The 10 most recently updated of 36 ClinicalTrials.gov registrations naming Silver Nitrate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

Frequently asked questions

How does Silver Nitrate work?
Mechanism-of-action class: Protein Synthesis Inhibitors.
What is Silver Nitrate used for?
According to FDA labeling, Silver Nitrate carries indications including: INDICATIONS: For cauterization of skin or mucous membrane and for removing warts and granulated tissue.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
What class of drug is Silver Nitrate?
Silver Nitrate is classified as Silver compounds, Protein Synthesis Inhibitors, Cellular Growth Phase Arrest.
What are the brand names for Silver Nitrate?
Silver Nitrate is marketed under brand names including Avoca, Styptstix.
What are the contraindications for Silver Nitrate?
Silver Nitrate labeling lists contraindications including: Silver salts stain tissue black due to deposition of reduced silver. The stain gradually disappears within a period of two weeks.. Always consult the full prescribing information and a clinician.
Note. Data for silver-nitrate is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.

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