Sodium Ascorbate

Mechanism-of-action classes: Enzyme Interactions; Free Radical Scavenging Activity.

Allergen Warning Contains fish gelatin and soy oil.

• Aug 2, 2006NDANDA021881Salix Pharms
• Jan 25, 2012ANDAANDA090145Novel Labs Inc
• May 4, 2018NDANDA209381Salix

1. 1Vomiting58418%
2. 2Nausea46215%
3. 3Drug Ineffective2678.4%
4. 4Diarrhoea2176.9%
5. 5Dehydration1875.9%
6. 6Abdominal Pain1825.7%
7. 7Headache1765.6%
8. 8Malaise1554.9%
9. 9Dizziness1434.5%
10. 10Product Taste Abnormal1414.5%
11. 11Dyspnoea1364.3%
12. 12Pyrexia1294.1%
13. 13Asthenia1264.0%
14. 14Hyponatraemia1253.9%
15. 15Fatigue1233.9%

Recent PubMed references pinned to Sodium Ascorbate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Targeting oxidative stress pathways in epilepsy: mechanistic insights into the role of ascorbic acid.
  Molecular biology reports · 2026 · Desai M, Malik S, Singh A, et al.
  PMID 42240857DOI 10.1007/s11033-026-12077-2
• Dual-mechanism vitamin C delivery by polyethylene glycol-23 glyceryl distearate-based niosomes via SVCT2 induction and enhanced transdermal penetration.
  Drug delivery · 2026 · Miyoshi T, Keller BC, Nakagawa S, et al.
  PMID 42217232DOI 10.1080/10717544.2026.2681287
• Effect of calcium ascorbate and maltitol on calcium signaling and genes of cell wall and membrane synthesis in yeast under freeze-thaw cycle.
  Food microbiology · 2026 · Xie D, Zheng J, Zhao L, et al.
  PMID 42215203DOI 10.1016/j.fm.2026.105123
• Hemoglobin-assisted, ZIF-derived porous bimetallic FeCo/N-C nanozyme with high oxidase-like activity for colorimetric sensing.
  Mikrochimica acta · 2026 · Wang Z, Chen Y, Lin X, et al.
  PMID 42209727DOI 10.1007/s00604-026-08155-8
• Vitamin C mitigates early auditory cortical hyperexcitability and antioxidant imbalance induced by acute intermittent hypoxia.
  Experimental brain research · 2026 · Wu Y, Li T, Cao W, et al.
  PMID 42207332DOI 10.1007/s00221-026-07310-0
• A Randomized, Double-Blind, Placebo-Controlled Trial of an Ayurvedic Herbal Formulation and Vitamin C/E on Vascular Function in Patients with Cardiovascular Disease.
  Medicina (Kaunas, Lithuania) · 2026 · Salerno JW, Xu S, Rainforth M, et al.
  PMID 42195225DOI 10.3390/medicina62050972
• Investigation of Sevoflurane-Induced Apoptotic Damage in Human Cardiomyocytes and the Protective Efficacy of Ascorbic Acid.
  Medicina (Kaunas, Lithuania) · 2026 · Aydoğan E, Övey İS, Karahan O, et al.
  PMID 42195198DOI 10.3390/medicina62050945
• Catalytic Reduction of H(2)O(2) by Polyvinylpyrrolidone Nickel Oxide Nanozymatic Activity and Colorimetric Sensing of Ascorbic Acid.
  Biosensors · 2026 · Rambevha M, Chavalala R, Mashazi P, et al.
  PMID 42187495DOI 10.3390/bios16050299

The 10 most recently updated of 1,213 ClinicalTrials.gov registrations naming Sodium Ascorbate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer
  Not yet recruiting · Phase 1 · Phase 2 · Interventional · 18 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  NCT06991738updated 2026-06-12
• A 4-week Study Investigating Two Targeted Brightening Serum (A and B) Versus 4% Hydroquinone in Women With Mild to Severe Full-face Hyperpigmentation
  Completed · Interventional · 18 enrolled · Revision Skincare
  NCT07644871updated 2026-06-12
• FILLing Protocols for the Right Bladder Volume at the RIGHT Time (FILLRIGHT)
  Not yet recruiting · Interventional · 20 enrolled · University Hospital, Brest
  NCT07642570updated 2026-06-11
• Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery
  Completed · Phase 3 · Interventional · 995 enrolled · Centre Hospitalier Universitaire, Amiens
  NCT02390505updated 2026-06-11
• Effect of Magnesium-, Vitamin C- and Grape Seed Extract-Enriched Date Bars on Perceived Stress and Salivary Cortisol Levels in Young Women
  Active not recruiting · Interventional · 30 enrolled · K.G. Razumovsky Moscow State University of Technologies and Management
  NCT07585422updated 2026-06-10
• Oxalate Formation From Ascorbic Acid
  Active not recruiting · Interventional · 90 enrolled · University of Alabama at Birmingham
  NCT04603898updated 2026-06-09
• Urinary Vitamin C Loss in Diabetic Subjects
  Recruiting · Observational · 5,000 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  NCT00071526updated 2026-06-08
• Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women
  Completed · Phase 1 · Interventional · 50 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  NCT00862433updated 2026-06-08
• Evaluation of the Safety and Tolerability of a Brightening Treatment Paired With a Skincare Regimen
  Completed · Interventional · 11 enrolled · Revision Skincare
  NCT07501000updated 2026-06-05
• High Dose Ascorbic Acid (HDAA) in Patients With Plasma Cell Disorders
  Recruiting · Phase 1 · Interventional · 18 enrolled · University of Arkansas
  NCT06313502updated 2026-06-04

Frequently asked questions

How does Sodium Ascorbate work?

Mechanism-of-action classes: Enzyme Interactions; Free Radical Scavenging Activity.

What class of drug is Sodium Ascorbate?

Sodium Ascorbate is classified as Enzyme Interactions, Free Radical Scavenging Activity, Cellular Activity Alteration.

What are the brand names for Sodium Ascorbate?

Sodium Ascorbate is marketed under brand names including Hemocyte Plus, MoviPrep, Tandem Plus.