Tocopherol
/api/v1/drug/tocopherolBoxed warning
Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.
Indications
Sourced from openFDA- PNV-DHA is a multivitamin/multimineral nutritional supplement indicated for use in the dietary management of patients with nutritional deficiencies or are in need of nutritional supplementation.
Contraindications
Sourced from openFDA- This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.contraindicated
Dosage & administration
Sourced from openFDABefore, during and/or after pregnancy, one softgel daily or as directed by a physician.
Warnings & precautions
Sourced from openFDAIngestion of more than 3 grams of omega-3 fatty acids (such as DHA) per day has been shown to have potential antithrombotic effects, including an increased bleeding time and International Normalized Ratio (INR). Administration of omega-3 fatty acids should be avoided in patients taking anticoagulants and in those known to have an inherited or acquired predisposition to bleeding.
Adverse reactions
Sourced from openFDAAllergic sensitization has been reported following both oral and parenteral administration of folic acid.
Approval history
Sourced from openFDA- Feb 21, 2001NDANDA021265Sandoz Canada Inc
- Apr 9, 2026ANDAANDA210273Apotex
- Apr 9, 2026ANDAANDA210672Apotex
FAERS reports
- 1Fatigue286.0%
- 2Nausea245.2%
- 3Premature Delivery245.2%
- 4Maternal Exposure During Pregnancy235.0%
- 5Pain224.8%
- 6Rash204.3%
- 7Arthralgia194.1%
- 8Off Label Use194.1%
- 9Dizziness173.7%
- 10Dyspnoea173.7%
- 11Diarrhoea163.5%
- 12Drug Ineffective163.5%
- 13Cough153.2%
- 14Pruritus153.2%
- 15Death143.0%
Literature
Recent PubMed references pinned to Tocopherol as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Enrichment of Platelet-Rich Fibrin Using Cobalamin and Alpha-Tocopherol to Modulate Growth Factor Release.Journal of visualized experiments : JoVE · 2026 · Ozcan M, Saygı H, Alkaya B, et al.PMID 42258410DOI 10.3791/71016
- Boosting salinity resilience and silymarin production in Silybum marianum: a sustainable strategy using mango-residue biochar and foliar α-tocopherol.BMC plant biology · 2026 · Youssef SM, Mohamed IAA, Rateb YSH, et al.PMID 42129636DOI 10.1186/s12870-026-08900-4
- Role of lipolysis and tocopherols in the formation of primary and secondary oxidation products during simulated gastrointestinal digestion of n-3 PUFA-rich oils.Food chemistry · 2026 · Beltrame G, Damerau A, Larsson K, et al.PMID 42096769DOI 10.1016/j.foodchem.2026.149454
- Screening of microalgal strains with elevated α-tocopherol levels and antioxidant capacity for biotechnological applications.Archives of microbiology · 2026 · Maltseva I, Yakoviichuk A, Maltseva S, et al.PMID 42030024DOI 10.1007/s00203-026-04923-5
- Alpha-tocopherol intake and status exhibit population-specific associations with metabolic syndrome among two Hispanic/Latinos populations.Nutrition research (New York, N.Y.) · 2026 · Costa ML, Mattei J, Batista LD, et al.PMID 42024979DOI 10.1016/j.nutres.2026.03.011
- Optimizing Bioactive Profiles in Kolovi Olive Oils: Impact of Destoning, Harvest Timing, and Postharvest Factors on Phenolic, Tocopherol, Lutein, and Squalene Content.Molecules (Basel, Switzerland) · 2026 · Martakos IC, Tzavellas IF, Soultani G, et al.PMID 41976221DOI 10.3390/molecules31071181
- A Self-Deliverable H(2)O(2)-Responsive Tocopherol Dimer for Enhanced Antioxidant and Liposomal Delivery.Molecules (Basel, Switzerland) · 2026 · Jo H, Kim A, Park C, et al.PMID 41976115DOI 10.3390/molecules31071071
- Metabolomic insights into homogentisic acid-mediated regulation of tocopherol enhancement in Monascus purpureus fermentation.Food microbiology · 2026 · Wu Q, Zhang N, Sun Y, et al.PMID 41963045DOI 10.1016/j.fm.2026.105072
Clinical trials
The 10 most recently updated of 737 ClinicalTrials.gov registrations naming Tocopherol as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Tocotrienol Supplementa as A Senolytic Agent in Middle-aged AdultsRecruiting · Interventional · 220 enrolled · National University of MalaysiaNCT07637487updated 2026-06-09
- Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese WomenCompleted · Phase 1 · Interventional · 50 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT00862433updated 2026-06-08
- A Study of Chiglitazar in Patients With Metabolic Dysfunction-associated Steatohepatitis and Type 2 Diabetes MellitusRecruiting · Phase 2 · Interventional · 300 enrolled · Shanghai Jiao Tong University School of MedicineNCT07303803updated 2026-06-03
- Immune-Mitochondrial Correction in Military RecruitsNot yet recruiting · Interventional · 200 enrolled · MIPO ClinicNCT07622147updated 2026-06-02
- Effect of Alpha Tocopherol and Psyllium on Lipid Levels in Dyslipidaemia PatientsCompleted · Phase 2 · Interventional · 60 enrolled · NUR International UniversityNCT07610304updated 2026-05-27
- Vitamin E Dosing StudyCompleted · Phase 2 · Interventional · 200 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT04801849updated 2026-05-14
- Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and DiabetesCompleted · Interventional · 28 enrolled · National Institutes of Health Clinical Center (CC)NCT02107976updated 2026-05-12
- Nodular Shrinking in Dupuytren DiseaseRecruiting · Phase 2 · Interventional · 80 enrolled · Universitaire Ziekenhuizen KU LeuvenNCT06321991updated 2026-05-11
- Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1Recruiting · Interventional · 720 enrolled · Virginia Commonwealth UniversityNCT04916327updated 2026-05-05
- Evaluation of Patient Satisfaction With Blephaderm as a Complementary Care in Post-eyelid SurgeryRecruiting · Observational · 30 enrolled · Laboratoires TheaNCT07234292updated 2026-05-04
Frequently asked questions
- What is Tocopherol used for?
- According to FDA labeling, Tocopherol carries indications including: PNV-DHA is a multivitamin/multimineral nutritional supplement indicated for use in the dietary management of patients with nutritional deficiencies or are in need of nutritional supplementation.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What are the brand names for Tocopherol?
- Tocopherol is marketed under brand names including Novipet Joint Support.
- What are the contraindications for Tocopherol?
- Tocopherol labeling lists contraindications including: This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.. Always consult the full prescribing information and a clinician.
tocopherol is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.