pharmacopeia
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/api/v1/drug/tolnaftate

Mechanism of action

Sourced from openFDA

Mechanism-of-action class: Squalene Monooxygenase Inhibitors.

Squalene Monooxygenase

Indications

Sourced from openFDA
  • Uses cures mose athlete's foot (tinea pedis) and ringworm (tinea corporis) ​prevents recurrence of athlete's foot with daily use relieves itching, burning and crackingICD-10: B35.3

Dosage & administration

Sourced from openFDA

Directions wash affected area and dry thoroughly shake can well and spray a thin layer over affected area twice daily (morning and night) or as directed by a doctor supervise children in the use of this product for athlete's foot: pay special attention to spaces between the toes; wear well-fitting, ventilated shoes, and change shoes and socks at least once daily use daily for 4 weeks if conditions persists, consult a doctor this product is not effective on the scalp or nails

Warnings & precautions

Sourced from openFDA

For external use only. Flammable: Keep away from heat, sparks and open flame. Contents under pressure. Do not puncture or incinerate. Do not store at temperature above 120°F. Use only as directed. Intentional misuse by deliberately concentrating and inhaling the contents can be harmful or fatal. When using this product avoid contact with the eyes Stop use and ask a doctor if irritation occurs if there is no improvement within 4 weeks Do not use on children under 2 years of age unless directed by a doctor. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

FAERS reports

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Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
1,383 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
  1. 1Drug Ineffective1228.8%
  2. 2Pain926.7%
  3. 3Fatigue866.2%
  4. 4Nausea846.1%
  5. 5Dyspnoea815.9%
  6. 6Diarrhoea735.3%
  7. 7Anxiety644.6%
  8. 8Off Label Use594.3%
  9. 9Headache564.0%
  10. 10Vomiting543.9%
  11. 11Acute Kidney Injury523.8%
  12. 12Pneumonia513.7%
  13. 13Arthralgia493.5%
  14. 14Asthenia493.5%
  15. 15Rash493.5%

Literature

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Recent PubMed references pinned to Tolnaftate as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

Clinical trials

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The 10 most recently updated of 34 ClinicalTrials.gov registrations naming Tolnaftate as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

Frequently asked questions

How does Tolnaftate work?
Mechanism-of-action class: Squalene Monooxygenase Inhibitors.
What is Tolnaftate used for?
According to FDA labeling, Tolnaftate carries indications including: Uses cures mose athlete's foot (tinea pedis) and ringworm (tinea corporis) ​prevents recurrence of athlete's foot with daily use relieves itching, burning and cracking. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
What class of drug is Tolnaftate?
Tolnaftate is classified as Other antifungals for topical use, Squalene Monooxygenase Inhibitors, Cellular Growth Phase Arrest.
What are the brand names for Tolnaftate?
Tolnaftate is marketed under brand names including Absorbine Jr. Antifungal, Blis-To-Sol, Cidacin, Clarus, Fungi-Gone, Fungi-Guard, Fungi-Nail Reformulated Mar 2019, Fungifoam.
Note. Data for tolnaftate is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.

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