Triprolidine
/api/v1/drug/triprolidineMechanism of action
Sourced from openFDAMechanism-of-action classes: Histamine H1 Receptor Antagonists; Monoamine Oxidase Inhibitors.
Indications
Sourced from openFDA- Uses temporarily relieves these symptoms due to hay fever (allergic rhinitis) or other upper respiratory allergies: runny nose sneezing itching of the nose or throat itchy, watery eyesICD-10: J30.9
Dosage & administration
Sourced from openFDADirections Do not exceed recommended dosage. use only the enclosed dropper. do not use enclosed dropper for any other drug products. AGE DOSE Adutls & Children 12 years of age or older: 2 mL (2.5 mg) every 4 to 6 hours, not to exceed 8 mL (10 mg) in 24 hours or as directed by a doctor. Children 6 to under12 years of age: 1 mL (1.25 mg) every 4 to 6 hours, not to exceed 4 mL (5 mg) in 24 hours or as directed by a doctor. Children under 6 years of age: Consult a docotor.
Warnings & precautions
Sourced from openFDADo not exceed recommended dosage. Ask a doctor before use if the child has a breathing problem such as emphysema or chronic bronchitis glaucoma Ask a doctor before use if the child is taking sedatives or tranquilizers When using this product excitability may occur, especially in children may cause drowsiness sedatives and tranquilizers may increase the drowsiness effect Stop use and ask a doctor if new symptoms occur Keep out of the reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
FAERS reports
- 1Psoriatic Arthropathy12244%
- 2Type 2 Diabetes Mellitus12244%
- 3Oedema12143%
- 4Pericarditis12143%
- 5Sinusitis12143%
- 6Pemphigus12043%
- 7Pyrexia12043%
- 8Joint Swelling11943%
- 9Urticaria11842%
- 10Nausea11742%
- 11Injury11641%
- 12Mobility Decreased11541%
- 13Pneumonia11541%
- 14Weight Increased11441%
- 15Gait Disturbance11039%
Literature
Recent PubMed references pinned to Triprolidine as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Efficacy of Triprolidine in the Treatment of Temporary Sleep Disturbance.Journal of clinical pharmacology · 2021 · Cravo AS, Shephard A, Shea T, et al.PMID 33768603DOI 10.1002/jcph.1861
- Bioavailability of Triprolidine as a Single Agent or in Combination With Pseudoephedrine: A Randomized, Open-Label Crossover Study in Healthy Volunteers.Clinical pharmacology in drug development · 2020 · Febbraro S, Shea T, Cravo AS, et al.PMID 32133778DOI 10.1002/cpdd.777
- Spinal sensory and motor blockade by intrathecal doxylamine and triprolidine in rats.The Journal of pharmacy and pharmacology · 2018 · Tzeng JI, Chiu CC, Wang JJ, et al.PMID 30251371DOI 10.1111/jphp.13017
- Development and validation of a rapid stability indicating HPLC-method using monolithic stationary phase and two spectrophotometric methods for determination of antihistaminic acrivastine in capsules.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2014 · Gouda AA, Hashem H, Jira T, et al.PMID 24813276DOI 10.1016/j.saa.2014.04.015
- Development and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous determination of acrivastine and pseudoephedrine in human plasma and its application in pharmacokinetics.Arzneimittel-Forschung · 2012 · He JC, Feng EF, Liu M, et al.PMID 22936420DOI 10.1055/s-0032-1314877
- Solubility-modulated asymmetric membrane tablets of triprolidine hydrochloride: statistical optimization and evaluation.AAPS PharmSciTech · 2012 · Dev R, Kumar A, Pathak K, et al.PMID 22183255DOI 10.1208/s12249-011-9738-3
- ["Of snakes and crocodiles": central side effects of nose drops and facts about rhinitis medicamentosa].Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege · 2011 · Bielenberg JPMID 22029138
- Chromatographic separation and spectroscopic characterization of the E/Z isomers of acrivastine.Chirality · 2011 · Davadra PM, Dabhi B, Singh MK, et al.PMID 21953883DOI 10.1002/chir.21022
Frequently asked questions
- How does Triprolidine work?
- Mechanism-of-action classes: Histamine H1 Receptor Antagonists; Monoamine Oxidase Inhibitors.
- What is Triprolidine used for?
- According to FDA labeling, Triprolidine carries indications including: Uses temporarily relieves these symptoms due to hay fever (allergic rhinitis) or other upper respiratory allergies: runny nose sneezing itching of the nose or throat itchy, watery eyes. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Triprolidine?
- Triprolidine is classified as Other antihistamines for systemic use, Histamine H1 Receptor Antagonists, Monoamine Oxidase Inhibitors, Decreased Histamine Activity.
- What are the brand names for Triprolidine?
- Triprolidine is marketed under brand names including A-Phedrin, Aphedrid, Flonase Nighttime, Genac brand of pseudoephedrine/triprolidine, Pediaclear Childrens, Vi-Sudo, Wal-Act.
triprolidine is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.