Uric Acid
US-FDASourced from openFDA
GET
/api/v1/drug/uric-acidIndications
Sourced from openFDA- For the temporary relief of minor joint pain or swelling, general muscle pain or stiffness, or dry, itchy skin due to sensitivity to phenolic compounds found in foods or other products.*
Dosage & administration
Sourced from openFDADIRECTIONS Place drops under tongue 30 minutes before/after meals. Adults and children 12 years and over: Take 10 drops up to 3 times per day. Consult a physician for use in children under 12 years of age.
Warnings & precautions
Sourced from openFDAIn case of overdose, get medical help or contact a poison control center right away. Keep out of the reach of children. If pregnant or breastfeeding, ask a healthcare professional before use.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
22 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Chronic Kidney Disease627%
- 2End Stage Renal Disease523%
- 3Acute Kidney Injury418%
- 4Dyspnoea418%
- 5Renal Failure418%
- 6Hypertension314%
- 7Nephrogenic Anaemia314%
- 8Oxygen Saturation Decreased314%
- 9Cough29.1%
- 10Decreased Appetite29.1%
- 11Drug Ineffective29.1%
- 12Heart Rate Increased29.1%
- 13Hyperparathyroidism Secondary29.1%
- 14Hyponatraemia29.1%
- 15Muscular Weakness29.1%
Literature
Recent PubMed references pinned to Uric Acid as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Uric acid, vitamin D, and left ventricular hypertrophy: Unveiling cardiovascular risks - a retrospective cross-sectional study.Medicine · 2026 · Abdallah EA, Elzorkany KMA, AlSahlawi M, et al.PMID 42260814DOI 10.1097/MD.0000000000049086
- Serum Uric Acid as a Sex-Dependent Risk Marker of Post-Stroke Epilepsy After Acute Ischemic Stroke: Complementary Mendelian Randomization and Cohort Analyses.CNS neuroscience & therapeutics · 2026 · Cheng Y, Li J, Yang Y, et al.PMID 42257821DOI 10.1002/cns.70970
- Serum uric acid levels and cardiorenal complication prevalence in hypertensive patients before and after the COVID-19 pandemic: a retrospective cross-sectional study from a tertiary traditional Chinese medicine hospital.Frontiers in endocrinology · 2026 · Yuan J, Hua P, He X, et al.PMID 42255435DOI 10.3389/fendo.2026.1830233
- Tart cherry intake and serum uric acid: Meta-analysis of randomized controlled trials and evidence from network pharmacology.Asia Pacific journal of clinical nutrition · 2026 · Zhang Z, Feng Z, Yan W, et al.PMID 42242852DOI 10.6133/apjcn.202606_35(3).0008
- Association between uric acid to high-density lipoprotein cholesterol ratio (UHR) and osteoporosis in type 2 diabetes with MASLD.Asia Pacific journal of clinical nutrition · 2026 · Li S, Yang Y, Tian G, et al.PMID 42242850DOI 10.6133/apjcn.202606_35(3).0006
- Uric acid alleviates the inflammatory response in LPS-induced BV2 cells and MPTP-induced PD mice by resisting ferroptosis through the Nrf2 signalling pathway.Redox report : communications in free radical research · 2026 · Zhou D, Xiong T, Yang B, et al.PMID 42241031DOI 10.1080/13510002.2026.2668238
- Transcriptome sequencing combined with experimental verification to explore potential key genes related to uric acid in diabetic retinopathy.PloS one · 2026 · Liang H, Yang T, Lu F, et al.PMID 42228736DOI 10.1371/journal.pone.0350132
- Uric Acid-to-Albumin Ratio Is Associated with Left Ventricular Diastolic Function in Patients with No Significant Perfusion Abnormality.International heart journal · 2026 · Kawaguchi T, Fukuda Y, Hironobe N, et al.PMID 42219327DOI 10.1536/ihj.25-673
Clinical trials
The 10 most recently updated of 369 ClinicalTrials.gov registrations naming Uric Acid as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)Recruiting · Phase 2 · Interventional · 150 enrolled · ProtalixNCT07280156updated 2026-06-11
- Pacritinib With Aza for Upfront Myelodysplastic SyndromeNot yet recruiting · Phase 1 · Phase 2 · Interventional · 25 enrolled · Thomas Jefferson UniversityNCT07387354updated 2026-06-10
- Immediate Prescription of a Hypouricemic Treatment, Febuxostat, Compared to Its Delayed AdministrationRecruiting · Phase 3 · Interventional · 128 enrolled · University Hospital, RouenNCT05109936updated 2026-06-08
- Loncastuximab Tesirine and Venetoclax for Relapsed/ Refractory Non-Hodgkin LymphomaActive not recruiting · Phase 1 · Interventional · 23 enrolled · Paolo Caimi, MDNCT05053659updated 2026-06-05
- Empiric Versus Selective Prevention Strategies for Kidney Stone DiseaseCompleted · Phase 4 · Interventional · 56 enrolled · Vanderbilt University Medical CenterNCT05365477updated 2026-06-03
- Tart Cherry Citrate Effervescent Tablet for Urate-Lowering Therapy in Participants With Asymptomatic HyperuricemiaNot yet recruiting · Interventional · 196 enrolled · Beijing Zhecheng Biotechnology Co., Ltd.NCT07613138updated 2026-06-03
- Probiotic-Uricase Complex Preparation for Improving Uric Acid Metabolism in Patients With HyperuricemiaNot yet recruiting · Interventional · 45 enrolled · Maanshan Shiqiye HospitalNCT07613164updated 2026-05-29
- Renal Dysfunction in Patients With Inflammatory Bowel Disease and the General Population (NEPHRO-IBD)Recruiting · Observational · 6,000 enrolled · Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i AdministracjiNCT07593352updated 2026-05-18
- A Study of IN026 in Participants With Refractory GoutNot yet recruiting · Phase 1 · Interventional · 16 enrolled · Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyNCT07587684updated 2026-05-14
- Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis SyndromeCompleted · Phase 4 · Interventional · 10 enrolled · M.D. Anderson Cancer CenterNCT04745910updated 2026-05-06
Frequently asked questions
- What is Uric Acid used for?
- According to FDA labeling, Uric Acid carries indications including: For the temporary relief of minor joint pain or swelling, general muscle pain or stiffness, or dry, itchy skin due to sensitivity to phenolic compounds found in foods or other products.*. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
Note. Data for
uric-acid is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.