Vitamin B12

Mechanism-of-action class: Enzyme Interactions.

Before, during and/or after pregnancy, one tablet daily, with a meal, or as directed by a licensed healthcare practitioner regardless of lactation status.

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Recent PubMed references pinned to Vitamin B12 as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Associations between vitamin B6 and vitamin B12 intake and lung function: A cross-sectional study based on NHANES 2007 to 2012.
  Medicine · 2026 · Wang W, Gu Y
  PMID 42260844DOI 10.1097/MD.0000000000049118
• Enrichment of Platelet-Rich Fibrin Using Cobalamin and Alpha-Tocopherol to Modulate Growth Factor Release.
  Journal of visualized experiments : JoVE · 2026 · Ozcan M, Saygı H, Alkaya B, et al.
  PMID 42258410DOI 10.3791/71016
• Association between proton pump inhibitor use and vitamin B12 deficiency: a retrospective cohort study in primary care centers in Riyadh, Saudi Arabia.
  Annals of Saudi medicine · 2026 · Alanazi S, Bin Sulaiman N, Aldahoul SK, et al.
  PMID 42251516DOI 10.5144/0256-4947.2026.159
• Effect of NSAIDs, melatonin, vitamin D and vitamin B12 chronotherapy on postoperative recovery after third molar surgical extraction: A pilot randomized crossover placebo-controlled trial.
  Oral and maxillofacial surgery · 2026 · Abusamak M, Pérez-González F, Ruiz LV, et al.
  PMID 42230417DOI 10.1007/s10006-026-01582-0
• Vitamin B12 supplementation for growth, development, and cognition in children.
  The Cochrane database of systematic reviews · 2026 · Larvie DY, Güitrón Leal CE, Venkatramanan S, et al.
  PMID 42227307DOI 10.1002/14651858.CD015264.pub2
• Vitamin B(12) Supplementation: Is More Always Better?
  Nutrients · 2026 · Yepes-Calderón M, Doorenbos CSE, Stegmann ME, et al.
  PMID 42197057DOI 10.3390/nu18101597
• Red Blood Cell Parameters, Iron Metabolism and Vitamin B12 Status in Children with Obesity: Associations with Diet and Obesity-Related Complications.
  Nutrients · 2026 · Cichocka-Mroczek E, Iwańska A, Goncerz D, et al.
  PMID 42197025DOI 10.3390/nu18101566
• Associations Between Concentrations of Vitamin D3, Vitamin B12, and Folate and the Well-Being of Medical Students.
  Nutrients · 2026 · Cieślikiewicz B, Bieńkowska A, Maksymowicz S, et al.
  PMID 42197019DOI 10.3390/nu18101559

The 10 most recently updated of 705 ClinicalTrials.gov registrations naming Vitamin B12 as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Host-Diet-Gut Interaction Post Vegan Diet in Pediatric Autoimmune Hepatitis.
  Recruiting · Interventional · 40 enrolled · Institute of Liver and Biliary Sciences, India
  NCT07118657updated 2026-06-12
• Clinical and Laboratory Study of Methylmalonic Acidemia
  Recruiting · Observational · 2,275 enrolled · National Human Genome Research Institute (NHGRI)
  NCT00078078updated 2026-06-11
• Biological Optimization Versus Standard Care in Post-POEM Achalasia Patients (BIO-POEM)
  Active not recruiting · Interventional · 166 enrolled · Asian Institute of Gastroenterology, India
  NCT07620899updated 2026-06-02
• Immune-Mitochondrial Correction in Military Recruits
  Not yet recruiting · Interventional · 200 enrolled · MIPO Clinic
  NCT07622147updated 2026-06-02
• Anemia Therapy in Patients With Infective Endocarditis
  Recruiting · Phase 4 · Interventional · 74 enrolled · Rigshospitalet, Denmark
  NCT07523646updated 2026-05-29
• A Trial of Vitamin B12 in Septic Shock
  Completed · Phase 2 · Interventional · 20 enrolled · Medical College of Wisconsin
  NCT03783091updated 2026-05-27
• Vitamin B Complex for Inferior Alveolar Nerve Paresthesia Recovery
  Not yet recruiting · Phase 4 · Interventional · 50 enrolled · University of Sao Paulo
  NCT07592897updated 2026-05-20
• Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being
  Recruiting · Interventional · 20 enrolled · King's College London
  NCT07599930updated 2026-05-20
• Effect of a Food Intervention With a Prebiotic Alone or Combined With B-vitamins on Gut Microbiota Diversity, Inflammation and Mental Health Outcomes in Older Adults (GutFood)
  Recruiting · Interventional · 84 enrolled · University of Ulster
  NCT07592975updated 2026-05-18
• Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
  Active not recruiting · Phase 2 · Phase 3 · Interventional · 82 enrolled · SWOG Cancer Research Network
  NCT05096663updated 2026-05-18

Frequently asked questions

How does Vitamin B12 work?

Mechanism-of-action class: Enzyme Interactions.

What class of drug is Vitamin B12?

Vitamin B12 is classified as Vitamin B12 (cyanocobalamin and analogues), Vitamin B12, Enzyme Interactions, Cellular Activity Alteration.

What are the brand names for Vitamin B12?

Vitamin B12 is marketed under brand names including Animi-3 with Vitamin D, Concept OB, Dodex, Eldertonic, Ellis Tonic, Ferocon, Ferralet 90, Ferraplus.