Vitamin E
GET
/api/v1/drug/vitamin-eMechanism of action
Sourced from openFDAMechanism-of-action class: Free Radical Scavenging Activity.
Indications
Sourced from openFDA- Effectively relieves eye irritation,redness, swelling and itchingcaused by styes, chalazionsand blepharitis
Dosage & administration
Sourced from openFDA1. Wash the affected area withwarm water first and dry it. 2. Apply 2 or 3 drops to theaffected areas and gentlymassage with a clean finger withcircular motions for 2 minutes tillthe skin absorbs the serum. 3. Apply it 2-3 times a day for thebest result. 4. Continue to use for 3-5 daysafter symptoms resolve to preventa recurrence
Warnings & precautions
Sourced from openFDAFor external use only keep outof the reach of young children.Do not use it on children under5 years of age unless directedby a doctor.
FAERS reports
Reference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. Counts reflect reporting volume — how often a reaction was reported, not how often it occurs. For decision-grade use, consult openFDA and the FAERS Public Dashboard directly.
30,966 total reports matchedLatest report Share = reports listing the reaction ÷ total matched reports. Rows can sum to >100% because a single report often lists multiple reactions.
- 1Fatigue2,7849.0%
- 2Nausea2,4347.9%
- 3Diarrhoea2,2537.3%
- 4Drug Ineffective2,1086.8%
- 5Headache2,0576.6%
- 6Pain1,9106.2%
- 7Dizziness1,8075.8%
- 8Dyspnoea1,7315.6%
- 9Arthralgia1,6465.3%
- 10Asthenia1,5304.9%
- 11Fall1,4604.7%
- 12Weight Decreased1,4094.6%
- 13Pain In Extremity1,2414.0%
- 14Vomiting1,2063.9%
- 15Off Label Use1,1983.9%
Literature
Recent PubMed references pinned to Vitamin E as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.
- Enrichment of Platelet-Rich Fibrin Using Cobalamin and Alpha-Tocopherol to Modulate Growth Factor Release.Journal of visualized experiments : JoVE · 2026 · Ozcan M, Saygı H, Alkaya B, et al.PMID 42258410DOI 10.3791/71016
- Saroglitazar and vitamin E vs. lifestyle interventions in metabolic dysfunction associated steatotic liver disease: A 3-arm randomised study.The Indian journal of medical research · 2026 · Tiwari AK, Singh G, Kumar V, et al.PMID 42237829DOI 10.25259/IJMR_2511_2025
- δ-Tocotrienol re-sensitizes vemurafenib-resistant melanoma cells to BRAF inhibition via modulation of AKT signaling.Food research international (Ottawa, Ont.) · 2026 · Giannitti G, Marchesi S, Garavaglia R, et al.PMID 42215124DOI 10.1016/j.foodres.2026.119457
- Genetic Causal Association Between Vitamin E and Depression: A Two-Sample Mendelian Randomization Study.Brain and behavior · 2026 · Zhao D, Long X, Wang J, et al.PMID 42213642DOI 10.1002/brb3.71510
- A Randomized, Double-Blind, Placebo-Controlled Trial of an Ayurvedic Herbal Formulation and Vitamin C/E on Vascular Function in Patients with Cardiovascular Disease.Medicina (Kaunas, Lithuania) · 2026 · Salerno JW, Xu S, Rainforth M, et al.PMID 42195225DOI 10.3390/medicina62050972
- Correlation between oxidative stress and inflammation with metabolomics profile in skeletal muscle of ageing animal model and its modulation by tocotrienol-rich fraction.British journal of biomedical science · 2026 · Saud Gany SL, Mohd Sahardi NFN, Tan JK, et al.PMID 42181963DOI 10.3389/bjbs.2026.16208
- Protective Effect of Vitamin E Against Vancomycin-Induced Nephrotoxicity: A Large-Scale Electronic Medical Record Study From Japan.Basic & clinical pharmacology & toxicology · 2026 · Nakanishi S, Imai S, Saito M, et al.PMID 42168788DOI 10.1111/bcpt.70245
- Timing of Antioxidant Pretreatment With Melatonin, Vitamin C, and Vitamin E in Ischemia-Reperfusion Injury: A Rat Inferior Epigastric Island Flap Model.Microsurgery · 2026 · Sirkeci CB, Yalcin CE, Aydın SY, et al.PMID 42157414DOI 10.1002/micr.70241
Clinical trials
The 10 most recently updated of 886 ClinicalTrials.gov registrations naming Vitamin E as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.
- Tocotrienol Supplementa as A Senolytic Agent in Middle-aged AdultsRecruiting · Interventional · 220 enrolled · National University of MalaysiaNCT07637487updated 2026-06-09
- Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese WomenCompleted · Phase 1 · Interventional · 50 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT00862433updated 2026-06-08
- A Study of Chiglitazar in Patients With Metabolic Dysfunction-associated Steatohepatitis and Type 2 Diabetes MellitusRecruiting · Phase 2 · Interventional · 300 enrolled · Shanghai Jiao Tong University School of MedicineNCT07303803updated 2026-06-03
- Immune-Mitochondrial Correction in Military RecruitsNot yet recruiting · Interventional · 200 enrolled · MIPO ClinicNCT07622147updated 2026-06-02
- Effect of Alpha Tocopherol and Psyllium on Lipid Levels in Dyslipidaemia PatientsCompleted · Phase 2 · Interventional · 60 enrolled · NUR International UniversityNCT07610304updated 2026-05-27
- Validation of the Snouda Metabolic Score for Phenotyping and Guiding Reversal in Type 2 DiabetesNot yet recruiting · Interventional · 150 enrolled · Salah SnoudaNCT07606872updated 2026-05-26
- Tretinoin and Arsenic Trioxide With or Without Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated Acute Promyelocytic LeukemiaRecruiting · Phase 2 · Interventional · 151 enrolled · M.D. Anderson Cancer CenterNCT01409161updated 2026-05-20
- Preventive Effect of Prophylactic Oral Antibiotics Against Cholangitis After Kasai PortoenterostomyRecruiting · Interventional · 356 enrolled · Children's Hospital of Fudan UniversityNCT05925309updated 2026-05-15
- Vitamin E Dosing StudyCompleted · Phase 2 · Interventional · 200 enrolled · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT04801849updated 2026-05-14
- Vitamin D3 for Moderate to Mild Traumatic Brain Injury: A Randomized Trial on Inflammation and Recovery (VIMOT)Recruiting · Phase 2 · Interventional · 240 enrolled · Lagos State UniversityNCT07269457updated 2026-05-13
Frequently asked questions
- How does Vitamin E work?
- Mechanism-of-action class: Free Radical Scavenging Activity.
- What is Vitamin E used for?
- According to FDA labeling, Vitamin E carries indications including: Effectively relieves eye irritation,redness, swelling and itchingcaused by styes, chalazionsand blepharitis. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.
- What class of drug is Vitamin E?
- Vitamin E is classified as Other plain vitamin preparations, Free Radical Scavenging Activity, Decreased Vitamin Uptake and Modification.
- What are the brand names for Vitamin E?
- Vitamin E is marketed under brand names including Aquasol E, Encora Capsule, Hemax, Lactocal, Liq-10, MVC-Fluoride, Macuvite with Lutein, Multi-Delyn.
Note. Data for
vitamin-e is illustrative MVP content compiled from public sources. pharmacopeia is for educational and informational use only and is not a substitute for professional medical advice.