Zinc Bromide

• PSORIZIDE ® ULTRA is indicated for the treatment of moderate to severe eczema, atopic dermatitis, seborrhea and seborrheic dermatitis. It has been found to work well with variety of combination therapies.ICD-10: L20.9

• Although there are no known contraindications, patients who are allergic to any PSORIZIDE ® ULTRA ingredient should consult a physician prior to taking the medication.contraindicated

Absorption of nickel sulphate is variable among individuals. For maximum absorption, tablets should be taken orally at the beginning of the day (or any convenient time after having taken nothing but water for at least 7 hours). Take nothing but water for one hour after taking medication to aid absorption. Weight Starting Dose Max. Dose 50-100 lbs ½ tablet 1 tablet 100-150 lbs 1 tablet 2 tablets 150-200 lbs 2 tablets 4 tablets over 200 lbs 3 tablets 6 tablets In the setting of renal impairment, dosage should be adjusted and serum nickel and bromide levels should be followed. Steady state trough level should be drawn prior to ingesting the day's dose after one week of dosing or at appropriate intervals. Target trough serum nickel level is 20-40 mcg/L. (Warning: post dose peak levels are unreliable.) Treatment duration depends on the individual. Increase dose as needed on a monthly basis. Maintenance phase In order to maintain symptomatic relief, medication may be continued at the same or reduced initial phase dose level.

Do not use if imprinted seal under bottle cap is missing or broken. Do not use if pregnant or nursing. If allergic to nickel or metal objects such as jewelry or if there is a history of blistering hand eczema, see PRECAUTIONS for hypersensitivity information. Lactose intolerant patients may have gastrointestinal difficulty. This has very rarely been reported at the doses used.

PSORIZIDE ® ULTRA contains low doses of active ingredients. Therefore there are minimal known side effects. (see PRECAUTIONS for hypersensitivity information)

Pregnancy Pregnancy category C Animal reproduction studies have not been conducted with PSORIZIDE ® ULTRA. PSORIZIDE ® ULTRA should not be given to a pregnant woman.

Potassium bromide toxicity Indications of toxicity due to oral overdosage of bromide may include nausea, vomiting, apathy, disturbed coordination, loss of memory, drowsiness, loss of emotional control, agitation, hallucination, tremors, depressed reflexes, stupor, and coma. Acute toxic reactions in humans have been reported at doses as low as 1000 mg. 21 This level is 67 times the dose received in one tablet of PSORIZIDE ® ULTRA. Nickel sulphate toxicity The oral rat LD 50 for nickel sulphate hexahydrate is 275 mg/kg. 19 Symptoms of toxicity due to oral overdosage of nickel sulphate may include nausea, vomiting, abdominal discomfort, diarrhea, giddiness, lassitude, headaches, cough, and shortness of breath. 20 The lowest observed transitory toxic effects from human ingestion of soluble nickel salts is approximately 8 mg nickel/kg body weight. 20 This is 80 times the maximum dose recommended for PSORIZIDE ® ULTRA. (See below ).

Recent PubMed references pinned to Zinc Bromide as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Accuracy of a whole-body single-photon emission computed tomography with a thallium-bromide detector: Verification via Monte Carlo simulations.
  Medical physics · 2025 · Ito T, Hitomi K, Ljungberg M, et al.
  PMID 40017160DOI 10.1002/mp.17724
• A submillimeter bundled microtubular flow battery cell with ultrahigh volumetric power density.
  Proceedings of the National Academy of Sciences of the United States of America · 2023 · Wu Y, Zhang F, Wang T, et al.
  PMID 36595700DOI 10.1073/pnas.2213528120
• Enhanced Performance of Zn/Br Flow Battery Using N-Methyl-N-Propylmorpholinium Bromide as Complexing Agent.
  International journal of molecular sciences · 2021 · Jiménez-Blasco U, Moreno E, Cólera M, et al.
  PMID 34502193DOI 10.3390/ijms22179288
• Ni-Catalyzed Arylbenzylation of Alkenylarenes: Kinetic Studies Reveal Autocatalysis by ZnX(2) *.
  Angewandte Chemie (International ed. in English) · 2021 · Dhungana RK, Sapkota RR, Wickham LM, et al.
  PMID 34427992DOI 10.1002/anie.202110459
• Regioselective Monobromination of Phenols with KBr and ZnAl-BrO(3)(-)-Layered Double Hydroxides.
  Molecules (Basel, Switzerland) · 2020 · Wang L, Feng C, Zhang Y, et al.
  PMID 32085603DOI 10.3390/molecules25040914
• Active Micromotor Systems Built from Passive Particles with Biomimetic Predator-Prey Interactions.
  ACS nano · 2020 · Mou F, Li X, Xie Q, et al.
  PMID 31860277DOI 10.1021/acsnano.9b05996
• Visible-light-driven Ag/AgBr/ZnFe(2)O(4) composites with excellent photocatalytic activity for E. coli disinfection and organic pollutant degradation.
  Journal of colloid and interface science · 2018 · Xu Y, Liu Q, Liu C, et al.
  PMID 29100160DOI 10.1016/j.jcis.2017.10.077
• Can Biomimetic Zinc Compounds Assist a (3 + 2) Cycloaddition Reaction? A Theoretical Perspective.
  Journal of chemical theory and computation · 2017 · Bozkurt E, Soares TA, Rothlisberger U, et al.
  PMID 29073762DOI 10.1021/acs.jctc.7b00819

Frequently asked questions

What is Zinc Bromide used for?

According to FDA labeling, Zinc Bromide carries indications including: PSORIZIDE ® ULTRA is indicated for the treatment of moderate to severe eczema, atopic dermatitis, seborrhea and seborrheic dermatitis. It has been found to work well with variety of combination therapies.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What are the contraindications for Zinc Bromide?

Zinc Bromide labeling lists contraindications including: Although there are no known contraindications, patients who are allergic to any PSORIZIDE ® ULTRA ingredient should consult a physician prior to taking the medication.. Always consult the full prescribing information and a clinician.