Hyperammonaemia
also: Hyperammonemia
6 drugs1,060 FAERS reportsMedDRA PT
GET
/api/v1/reaction/hyperammonaemiaReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D022124
Elevated level of AMMONIA in the blood. It is a sign of defective CATABOLISM of AMINO ACIDS or ammonia to UREA.
Source: U.S. National Library of Medicine — MeSH (Hyperammonemia)
Drugs reporting Hyperammonaemia (6)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Pegzilarginase2100%
- 2Phenylbutyrate20212%
- 3Glycerol Phenylbutyrate15212%
- 4Asparaginase3110%
- 5Carglumic Acid547.4%
- 6Valproic Acid6192.0%
Related reactions
Other reactions most often co-reported on the same drug set. Ranked by Jaccard similarity over drug-id sets — pure data-derived co-occurrence, not a clinical relationship.
Literature
Recent PubMed references pinned to Hyperammonemia as a MeSH major topic. About the reaction term itself — not about any specific drug.
- [Therapeutic efficacy of ASS1 combined with LOLA in the treatment of hyperammonemia in mice].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025 · Luo T, Ming Z, Zou Z, et al.PMID 42032990DOI 10.11817/j.issn.1672-7347.2025.250577
- Fatal Non-Hepatic Hyperammonemia Post-Glofitamab: Ureaplasma and Genetic Susceptibility: A Case Report.Immunity, inflammation and disease · 2026 · Wu Y, Guo X, Wang X, et al.PMID 42010993DOI 10.1002/iid3.70443
- MassARRAY-based targeted detection of SLC22A5 mutations: A feasibility study for secondary screening of primary carnitine deficiency in newborns.Clinica chimica acta; international journal of clinical chemistry · 2026 · Gong L, Zhao J, Li L, et al.PMID 41974402DOI 10.1016/j.cca.2026.121001
- A Case of Refractory Hyperammonemia due to Pediatric Acute Liver Failure Treated With Two-Site Blood Purification Devices Prior to Liver Transplantation.Pediatric transplantation · 2026 · Tanimura S, Ide K, Matsumoto S, et al.PMID 41928383DOI 10.1111/petr.70308
- Long-term effects of L-carnitine on hyperammonemia and hepatic encephalopathy in patients with liver cirrhosis: a multicenter retrospective study.European journal of gastroenterology & hepatology · 2026 · Tani J, Moriya A, Tomonari T, et al.PMID 41870958DOI 10.1097/MEG.0000000000003171
- Case Report: Valproate Induced Hyperammonaemic Encephalopathy in a Psychiatric Inpatient.Psychopharmacology bulletin · 2026 · Cockill A, Stephenson CPMID 41821983DOI 10.64719/pb.16617
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.