Muscle Spasticity
1 drug2,972 FAERS reportsMedDRA PT
GET
/api/v1/reaction/muscle-spasticityReference statistics only. FAERS reports are voluntarily submitted and are not incidence rates, safety signals, or causal evidence. The drugs below are ranked by how often this reaction appears on FAERS reports for each drug — high share does not mean the drug caused the reaction, and absence from this list does not mean the reaction never occurred. This is not a symptom checker.
DefinitionNLM MeSH D009128
A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
Source: U.S. National Library of Medicine — MeSH (Muscle Spasticity)
Drugs reporting Muscle Spasticity (1)
Share = reports listing this reaction ÷ total matched reports for the drug. — means the upstream totals query failed at ingest and the denominator is unknown.
- 1Baclofen2,9723.4%
Literature
Recent PubMed references pinned to Muscle Spasticity as a MeSH major topic. About the reaction term itself — not about any specific drug.
- Early Intervention of Hemiplegic Shoulder Pain in the Context of Post-Stroke Shoulder Spasticity: A Canadian Cross-Sectional Survey.Toxins · 2026 · Kassam F, MacRae F, Lechner L, et al.PMID 42188630DOI 10.3390/toxins18050228
- Spinal mechanisms and feasibility of Dry Needling versus Botulinum Toxin Type A in post-stroke lower limb spasticity: A proof-of-concept randomized clinical trial protocol (STROKE-POC).PloS one · 2026 · Pujol-Fuentes C, Eeckhaut B, Fernández Carnero S, et al.PMID 42160369DOI 10.1371/journal.pone.0334571
- [Effectiveness of T (1) nerve root transection in treatment of spastic hand contracture in cerebral palsy].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026 · Xu Y, Wang T, Cai X, et al.PMID 42150911DOI 10.7507/1002-1892.202510056
- Intrathecal baclofen pump failure due to pain-induced autonomic dysreflexia.BMJ case reports · 2026 · Khawer A, Jain A, Naji L, et al.PMID 42134868DOI 10.1136/bcr-2025-271027
- Comparison Effects of Anodal Versus Cathodal Trans-Cranial Direct Current Stimulation Over Primary Motor Cortex on Lower Limb Muscles' Spasticity: A Randomized Clinical Trial Study.The European journal of neuroscience · 2026 · Bazghandi R, Delkhosh CT, Mahmoodi S, et al.PMID 42117320DOI 10.1111/ejn.70499
- Compound heterozygous variants in IRAK4 cause IRAK4 deficiency characterized by recurrent bacterial infections, brain calcification, and severe epilepsy.Gene · 2026 · Zhang J, Fan S, Xie L, et al.PMID 42103176DOI 10.1016/j.gene.2026.150199
Note. FAERS reports are voluntarily submitted and are NOT incidence rates, signals, or causal evidence. Counts reflect reporting volume, not how often a reaction occurs. Reference statistics only.