Allantoin

• uses Temporarily protects minor cuts, burns, scrapes, chafed, chapped, or cracked skin.

Directions Adults and children 2 years and over. For use as soak in bath, dissolve 1 bath bomb in warm tub of water, Soak for 10 to 30 minutes as needed, or as directed by doctor. Pat dry (do not rub) to leave a thin layer on the skin

For external use only. Keep out of reach of children Keep out of reach of children

in case of overdose seek medical help or contact a poison control center right away.

1. 1Nausea39412%
2. 2Vomiting2738.4%
3. 3Condition Aggravated2226.8%
4. 4Drug Ineffective2076.3%
5. 5Dyspnoea2036.2%
6. 6Abdominal Pain1915.9%
7. 7Fatigue1805.5%
8. 8Somnolence1805.5%
9. 9Weight Decreased1775.4%
10. 10Anaemia1614.9%
11. 11Dizziness1614.9%
12. 12Headache1604.9%
13. 13Asthenia1584.8%
14. 14Sepsis1534.7%
15. 15Constipation1524.7%

Recent PubMed references pinned to Allantoin as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• Photothermally enhanced drug release and anti-inflammatory effects of allantoin-loaded chitosan-based biomaterials incorporating melanin for transdermal drug delivery.
  International journal of biological macromolecules · 2026 · Kim K, Lee CM, Kim BK, et al.
  PMID 42190768DOI 10.1016/j.ijbiomac.2026.152708
• Self-Adaptive Allantoin@ZIF8 Nanocomposite Hydrogel with Resveratrol Synergy for MRSA-Infected Wound Regeneration.
  Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · Zhu Y, Liu D, Zhao M, et al.
  PMID 41837579DOI 10.1002/advs.202520614
• Coordinated N metabolism and NO signaling underlie allantoin-citrulline synergy in salt-stressed cucumber.
  BMC plant biology · 2026 · Amerian M, Gohari G, Panahirad S, et al.
  PMID 41634573DOI 10.1186/s12870-026-08146-0
• Foliar application of allantoin reinforces antioxidant defense and glyoxalase systems to confer tolerance against arsenic toxicity in rice (Oryza sativa L.).
  BMC plant biology · 2026 · Hasanuzzaman M, Alam S, Sultana A, et al.
  PMID 41593491DOI 10.1186/s12870-026-08192-8
• An allantoin-inducible glyoxylate utilization pathway in Pseudomonas aeruginosa.
  Microbiology (Reading, England) · 2025 · Parkhill SL, Little O, Askenasy I, et al.
  PMID 41369682DOI 10.1099/mic.0.001635
• Implications of exogenous allantoin in enhancing growth and development of Vitis vinifera L. cultivars under semi-arid condition.
  Scientific reports · 2025 · Bahmani A, Moharrampour S, Seyed Hajizadeh H, et al.
  PMID 41366024DOI 10.1038/s41598-025-31875-5
• Allantoin enhances growth and nutrient accumulation in Dioscorea opposita under saline-alkali stress through regulation of ion homeostasis and antioxidant capacity.
  Plant physiology and biochemistry : PPB · 2025 · Li C, Li S, Ma L, et al.
  PMID 41344264DOI 10.1016/j.plaphy.2025.110819
• Dual Regulation of the allF Operon by ArcA and AllS Enables Anaerobic Allantoin Utilization in Escherichia coli.
  Journal of microbiology and biotechnology · 2025 · Kim NY, Kim OB
  PMID 41016821DOI 10.4014/jmb.2507.07057

The 10 most recently updated of 27 ClinicalTrials.gov registrations naming Allantoin as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Elimination of Odor and Treatment of Malodorous Recalcitrant Wounds by Using Supraz and PRP-FG Versus Standard of Care
  Active not recruiting · Phase 2 · Phase 3 · Interventional · 40 enrolled · Mashhad University of Medical Sciences
  NCT05983302updated 2026-05-06
• Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis Bullosa
  Not yet recruiting · Phase 3 · Interventional · 80 enrolled · Paradigm Therapeutics
  NCT07482787updated 2026-03-20
• An Open Label Extension Safety Study to Evaluate SD-101 in Epidermolysis Bullosa
  Not yet recruiting · Phase 3 · Interventional · 80 enrolled · Paradigm Therapeutics
  NCT07482813updated 2026-03-19
• Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI
  Active not recruiting · Phase 1 · Interventional · 30 enrolled · University of Texas Rio Grande Valley
  NCT05589402updated 2026-03-06
• Effect of Topical Agents With Various Antioxidant Containts on Photodamage Skin Induced
  Completed · Phase 2 · Interventional · 11 enrolled · Universitas Padjadjaran
  NCT06170346updated 2025-04-08
• The Use of Arnica Montana in the Cicatrization of the Umbilical Cord
  Completed · Observational · 326 enrolled · Ospedale Buon Consiglio Fatebenefratelli
  NCT05958251updated 2024-09-19
• Effectiveness and Safety of Topical Hyaluronic Acid of Different Molecular Weights in Xerotic Skin Treatment
  Completed · Phase 3 · Interventional · 36 enrolled · Indonesia University
  NCT06178367updated 2024-04-30
• Effect of Kangaroo Mother Care on Oxidative Stress and Bonding
  Completed · Interventional · 40 enrolled · University of Health Sciences Lahore
  NCT06338410updated 2024-04-01
• A Single Group Study to Evaluate the Efficacy of a Cosmetic Product Line on Acne Symptoms
  Completed · Interventional · 36 enrolled · Menning Labs
  NCT06122467updated 2024-03-20
• Clinical Trial to Evaluate Safety and Efficacy of Jalosome® Soothing Gel.
  Unknown · Interventional · 57 enrolled · Welcare Industries SpA
  NCT05284487updated 2024-02-26

Frequently asked questions

What is Allantoin used for?

According to FDA labeling, Allantoin carries indications including: uses Temporarily protects minor cuts, burns, scrapes, chafed, chapped, or cracked skin.. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Allantoin?

Allantoin is classified as Decreased Skin Keratinization.

What are the brand names for Allantoin?

Allantoin is marketed under brand names including Anbesol Cold Sore Therapy, Berberex Wound Cleanser, Blister Armour, Chamois Glide, Mederma Advanced Scar, Mederma for Kids, Shing-Releev.