Aluminum Hydroxide

Mechanism-of-action classes: Acid-Base Activity; Electrolyte Activity.

• Uses relieves heartburn acid indigestion sour stomach

Directions shake well before using do not take more than 12 teaspoonfuls in 24 hours do not use the maximum dosage for more than 2 weeks dosage: 2 teaspoonfuls 5-6 times daily after meals and at bedtime followed by a sip of water if needed children under 12 years: ask a doctor

Ask a doctor or pharmacist before use if you are taking a prescription drug. Antacids may interact with certain prescription drugs. When using this product you may get constipated Stop use and ask a doctor if symptoms last more than 2 weeks If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.

1. 1Nausea5166.5%
2. 2Diarrhoea4916.2%
3. 3Vomiting4846.1%
4. 4Chronic Kidney Disease4786.0%
5. 5Dyspnoea4585.7%
6. 6Fatigue4465.6%
7. 7Acute Kidney Injury4365.5%
8. 8Headache4305.4%
9. 9Pain3714.6%
10. 10Off Label Use3604.5%
11. 11Pyrexia3434.3%
12. 12Drug Interaction3424.3%
13. 13Drug Ineffective3334.2%
14. 14Malaise3294.1%
15. 15Abdominal Pain Upper3053.8%

Recent PubMed references pinned to Aluminum Hydroxide as a MeSH major topic. Citations link to pubmed.ncbi.nlm.nih.gov.

• A novel composite of Mg-Al layered double hydroxide/aeolian sand for enhanced removal of fluoride from water.
  Environmental geochemistry and health · 2026 · Li Q, Jin Z, Zhou J, et al.
  PMID 42151459DOI 10.1007/s10653-026-03237-1
• Elaeis guineensis Jacq. as a Bioindicator of Aluminum Hydroxide-Induced Cytogenotoxicity in Root Meristems.
  Bulletin of environmental contamination and toxicology · 2026 · Quintero Caleño JD, Moreno Rozo LY, Salazar Mercado SA, et al.
  PMID 42149251DOI 10.1007/s00128-026-04254-7
• Macrophage-Mediated In Vivo Intracellular Crystallization of Aluminum Oxyhydroxide Adjuvant in Vaccine-Induced Granulomas.
  ACS applied materials & interfaces · 2026 · Pérez E, Navarro M, Ibarra A, et al.
  PMID 42062044DOI 10.1021/acsami.6c04089
• X-ray Investigation of the Aging Process of Aluminum Hydroxide Adjuvant in Protein-Based Vaccine Formulations Over a Short Period.
  Archives of Razi Institute · 2025 · Mohammad Reza H, Mohammad Z, Sara Z, et al.
  PMID 42058260DOI 10.32592/ARI.2025.80.4.1047
• The impact of aluminum recovery via sequential acid/alkali treatment on the settling, thickening, and dewatering performance of polyaluminum chloride (PAC) sludge.
  Waste management (New York, N.Y.) · 2026 · Liu J, Liu J, Zhang D, et al.
  PMID 41946110DOI 10.1016/j.wasman.2026.115516
• Remediation of cadmium-contaminated soils by mercaptosuccinic acid-intercalated hydrotalcite: Effects on soil quality and cadmium accumulation in rice.
  Journal of environmental management · 2026 · He L, Ding C, Nie M, et al.
  PMID 41905143DOI 10.1016/j.jenvman.2026.129506
• Geochemical modeling of rare earth element adsorption onto aluminum hydroxide and hydroxysulfate under variable sulfate conditions.
  Chemosphere · 2026 · Boothe-Lordon TJ, Cravotta CA 3rd, Tasker TL, et al.
  PMID 41863860DOI 10.1016/j.chemosphere.2026.144900
• Restoring the waters while polluting the food web - the unintended consequences of aluminum use in lake management.
  Aquatic toxicology (Amsterdam, Netherlands) · 2026 · Rybak M, Güngör YB, Książkiewicz Z, et al.
  PMID 41679012DOI 10.1016/j.aquatox.2026.107750

The 10 most recently updated of 393 ClinicalTrials.gov registrations naming Aluminum Hydroxide as an intervention. Registration is not evidence of efficacy or safety — reference crosswalk only.

• Safety and Immunogenicity of an Inactivated West Nile Virus Vaccine in Healthy Adults
  Active not recruiting · Phase 1 · Interventional · 30 enrolled · National Institute of Allergy and Infectious Diseases (NIAID)
  NCT06745921updated 2026-06-12
• A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes
  Active not recruiting · Phase 1 · Interventional · 140 enrolled · National Institute of Allergy and Infectious Diseases (NIAID)
  NCT07221162updated 2026-06-05
• Famotidine and Antacids for Treatment of Dyspepsia
  Recruiting · Phase 4 · Interventional · 80 enrolled · Stony Brook University
  NCT06241183updated 2026-06-02
• Safety and Efficacy of wSp Vaccine in Young Children
  Recruiting · Phase 2 · Interventional · 320 enrolled · Serum Life Science Europe GmbH
  NCT07216430updated 2026-06-02
• CDC-9 Inactivated Rotavirus Vaccine (IRV) Intramuscular (IM) Phase 1 Clinical Trial in Healthy Adults
  Completed · Phase 1 · Interventional · 50 enrolled · Centers for Disease Control and Prevention
  NCT06485258updated 2026-05-26
• Randomized Trial of COVID-19 Booster Vaccinations (Cobovax Study)
  Completed · Phase 4 · Interventional · 451 enrolled · The University of Hong Kong
  NCT05057169updated 2026-05-15
• Safety and Immunogenicity of Repeated Doses of ABvac40 in Patients With a-MCI or Vm-AD
  Completed · Phase 2 · Interventional · 134 enrolled · Araclon Biotech S.L.
  NCT03461276updated 2026-05-05
• Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine
  Completed · Phase 1 · Phase 2 · Interventional · 132 enrolled · National Institute of Allergy and Infectious Diseases (NIAID)
  NCT03284710updated 2026-05-04
• Alginate vs Sucralfate for GERD Symptomatic Relief
  Completed · Phase 2 · Phase 3 · Interventional · 140 enrolled · CMH Lahore Medical College and Institute of Dentistry
  NCT07310927updated 2026-04-21
• A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes
  Active not recruiting · Phase 3 · Interventional · 321 enrolled · Diamyd Medical AB
  NCT05018585updated 2026-04-15

Frequently asked questions

How does Aluminum Hydroxide work?

Mechanism-of-action classes: Acid-Base Activity; Electrolyte Activity.

What is Aluminum Hydroxide used for?

According to FDA labeling, Aluminum Hydroxide carries indications including: Uses relieves heartburn acid indigestion sour stomach. This is a reference summary of labeled uses, not medical advice or a treatment recommendation.

What class of drug is Aluminum Hydroxide?

Aluminum Hydroxide is classified as Aluminium compounds, Acid-Base Activity, Electrolyte Activity, Antacid, Increased Renal PO4-- Excretion.

What are the brand names for Aluminum Hydroxide?

Aluminum Hydroxide is marketed under brand names including Acid Gone, Almacone, Comfort Gel, Derma Gran, Gaviscon, Gaviscon Chewable, Gelusil, Maalox Max.